mal experiments have partly revealed those processes. It has been shown that part of plant ET may undergo hydrolysis to EA already in the stomach [Milala et al., 2017], while other researchers claimed ET to remain stable under conditions of that gastrointestinal segment [Sandhu et al., 2018]. There is no doubt that the large intestinal microbiota population with its huge enzymatic power acts as a paramount agent facilitating the hydrolysis of ET [Cerdá et al., 2005a,b; Ito et al., 2008; Sandhu et al., 2018]. Several researchers have reported that ET are not absorbed and prior to absorption must be metabolised by intestinal microbiota fi rst into EA and then into other molecules such as urolithins and nasutin [Milala et al., 2017; Saha et al., 2016]. Urolithins contain a 6H-dibenzo[b,d]pyran-6-one nucleus with different phenolic hydroxyl groups. There are several types of urolithins, namely urolithins D, C, A, B with a decreasing number of the phenolic hydroxyl groups, respectively [Toney et al., 2019]. Following intestinal absorption and hepatic biotransformation, the main metabolites circulating in blood stream are urolithin A glucuronide and urolithin A aglycone [Kawabata et al., 2019]. The production of urolithins is a common result of consuming ET with