Population growth, along with a rapid urban expansion, is imposing a heavy pressure on the planet’s finite resources. It is widely acknowledged that the building industry consumes large amounts of raw materials while generating waste and emissions. To set apart economic growth from environmental repercussions, the Circular Economy (CE) arose as an innovative paradigm that can offer a fast-track towards a sustainable built environment. This paper will tackle a research gap that academia and policymakers often highlighted, which is how can we apply CE to assets that are predominantly meant to be demolished and their resources wasted when they reach their end-of-life. Globally, the paradigm aims at erasing the waste concept, relying on renewable and regenerative sources, and keeping the materials, components, and systems in use at their highest value as long as possible. The concept’s implementation would attempt to consider the built environment as a closed-loop system wherein resources are viewed as a scarce commodity. Although the CE seems straightforward, translating the circular thinking to the building level might be a hardship. The following paper will attempt to shed light on how to promote CE in buildings that will ultimately lead to healthier, more efficient, and more sustainable cities on a broader scale. The proposed framework considers CE implementation strategies throughout the building’s lifecycle and mainly deals with three innovative aspects: wise resource management, building design approaches, and digitalization of the building industry. In this sense, this study will explore these game-changing factors that are considered paramount to concretize the concept in practice and provide a smooth pathway for CE uptake in buildings.