Impulse and mass transport in a cartilage bioreactor using the lattice Boltzmann method

Hussein, Mostafa; Esterl, S.; Pörtner, Ralf; Wiegandt, Katharina; Becker, Thomas

doi:10.1080/10618560802077806

Cited by 9 publications

(7 citation statements)

References 14 publications

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“…Furthermore, the method was used to model reaction kinetics in nasal tissue and proved comparable results (Schroeter et al, 2005). The same model was used to investigate the oxygen consumption by cartilage cells in a single-phase bioreactor and transport efficiencies were reported (Hussein et al, 2008). In this work, oxygen saturation levels in the nutrition exit are reported and compared with experimental results, shear and pressure distributions are compared with published measurements.…”

Section: Introductionmentioning

confidence: 88%

“…It is expected that the exit of the nutrition phase carries some dissolved oxygen. The flow field in the bioreactor is modelled using a decoupled system (Hussein et al, 2008), since the modeling of substrate transport independently is possible as long as the mass proportion between the substrate and the solvent is negligible which can be estimated as…”

Section: Numerical Descriptionmentioning

confidence: 99%

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On the lattice Boltzmann method simulation of a two-phase flow bioreactor for artificially grown cartilage cells

Hussein

Esterl

Pörtner

et al. 2008

Journal of Biomechanics

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Section: Introductionmentioning

confidence: 88%

Section: Numerical Descriptionmentioning

confidence: 99%

On the lattice Boltzmann method simulation of a two-phase flow bioreactor for artificially grown cartilage cells

Hussein

Esterl

Pörtner

et al. 2008

Journal of Biomechanics

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“…Additionally, the isothermal surfaces of both are surfaced in Figure 11, where the LBM isotherms are on the left and the exact are on the right. The mass transport validation has been extensively published in previous work of the authors Hussein, [7][8][9] where both diffusive and convective transports models have been deeply investigated.…”

Section: Thermal Solver Validationmentioning

confidence: 99%

An Innovative Micro-Modelling of Simultaneous Heat and Moisture Transfer during Bread Baking Using the Lattice Boltzmann Method

Hussein

Becker

2010

Food Biophysics

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A considerable fraction of the energy consumed in bread manufacturing is used for the baking process. A thorough understanding of internal moisture transfer mechanisms are important to optimise both the quality of the product and the economics of the process. From a transport phenomena point of view, bread baking has been considered as a simultaneous heat and mass transfer problem in a porous medium. Nevertheless, most efforts previously made have avoided modelling the phenomenon occurring in the microscale, although the mechanism occurs primarily in the microscale. In this work heat and moisture transfer models were developed to accomplish the mechanisms included, both in the microscale and the macroscale by means of Boltzmann's equation. Modelling and predictions of moisture transfer, heat transfer, modelling of effective moisture diffusivity, thermal conductivity and diffusivity have been investigated in this work. The microstructure in the dough samples was obtained using micro-computer tomography images from the samples prior to baking. The models were quantified and validated with measurements from the literature in order to assess the predictive models. The simulated crust development has shown a crust thickness of 0.8 cm, which is slightly higher than similar experimental results in which a dehydrated thickness of 0.5-0.6 cm was reported. The crust over-estimation in this work fits to the overheating occurring in the model. Additionally, investigations were made on the influence of different porosities (11-16%) of the bread; the boundary layer temperature at a porosity of 11% was reached after 25 min and after 17.5 min at a porosity of 16%. Therewith, the results showed that, with increasing porosity, the heat transfer rate towards the centre was higher, which matches the knowledge of experienced bakers.

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“…The appropriate physical values of the constants used in the Mechaelis-Menten equation for the human cartilage cells are listed in Table 4. The values of constants involved are obtained from previous experimental work made with the cartilage cells (Hussein et al 2008a).…”

Section: Fig 8 Comparison Between the Exact Solution And The Lbm Resmentioning

confidence: 99%

“…More recently, Anwar et al (2008) developed a LBM for simulating complex solute transport problems. Hussein et al (2008a) modeled the diffusion of oxygen enriched water in cartilage cell breeding reactor. The flow field was simulated using the lattice Boltzmann method while the oxygen diffusion was decoupled from the flow field then modeled using a finite difference diffusion-advection kinetic model.…”

Section: Introductionmentioning

confidence: 99%

An innovative lattice Boltzmann model for simulating Michaelis–Menten-based diffusion–advection kinetics and its application within a cartilage cell bioreactor

Sayed

Hussein

Becker

2009

Biomech Model Mechanobiol

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Lattice Boltzmann models (LBM) are rapidly showing their ability to simulate a lot of fluid dynamics problems that previously required very complex approaches. This study presents a LBM for simulating diffusion-advection transport of substrate in a 2-D laminar flow. The model considers the substrate influx into a set of active cells placed inside the flow field. A new innovative method was used to simulate the cells activity using the LBM by means of Michaelis-Menten kinetics. The model is validated with some numerical benchmark problems and proved highly accurate results. After validation the model was used to simulate the transport of oxygen substrates that diffuse in water to feed a set of active cartilage cells inside a new designed bioreactor.

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Impulse and mass transport in a cartilage bioreactor using the lattice Boltzmann method

Cited by 9 publications

References 14 publications

On the lattice Boltzmann method simulation of a two-phase flow bioreactor for artificially grown cartilage cells

On the lattice Boltzmann method simulation of a two-phase flow bioreactor for artificially grown cartilage cells

An Innovative Micro-Modelling of Simultaneous Heat and Moisture Transfer during Bread Baking Using the Lattice Boltzmann Method

An innovative lattice Boltzmann model for simulating Michaelis–Menten-based diffusion–advection kinetics and its application within a cartilage cell bioreactor

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