Imunomodulação de Fagócitos do Sangue Humano pelo Extrato de Strychnos Pseudoquina ST. HILL Adsorvido em Microesferas de Polietilenoglicol

Côrtes, Mayra Aparecida; França, Eduardo Luzía; Reinaque, Ana Paula Barcelos; Scherer, Edson Fredulin; Honório-França, Adenilda Cristina

doi:10.4322/polimeros.2013.085

Cited by 8 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This genus belongs to the Loganeaceae family, which comprises approximately 200 species distributed over the Americas, Africa, Australia, and Asia [20,21]. The target plant in the present study was Strychnos pseudoquina, popularly known as quina-do-campo or falsaquina, an arboreous species that is native to South America and commonly found in the Cerrado biome in Brazil [22].…”

Section: Introductionmentioning

confidence: 99%

Toxicity of Bioactive Compounds of Strychnos pseudoquina (Loganiaceae) in Spodoptera frugiperda (Noctuidae)

Souza,

Menezes,

Santos

et al. 2024

Sustainability

View full text Add to dashboard Cite

The objective of this study was to assess the toxicity of leaf and bark extracts of Strycns pseudoquina and their fractions, as well as flavonoids isolated from its bark, in a population of Spodoptera frugiperda. Crude bark and leaf extracts, as well as fractions of these extracts, were obtained using a rotary evaporator and different solvents; the ethyl acetate fraction was obtained, and flavonoid compounds were isolated, consisting mostly of 3-O-methylquercetin and minimally of strychnobiflavone. The crude extracts, extract fractions, and isolated flavonoids were applied separately to maize leaves, which were offered to S. frugiperda larvae; then, biological parameters of this insect population were evaluated. Toxic effects of topical applications of the isolated flavonoids on the larvae were also evaluated. The results highlighted the larvicidal effects of the crude bark extract and its fractions and the significant toxicity of this crude extract (LC50 = 0.048%), which was six times more toxic to larvae than its ethyl acetate fraction (LC50 = 0.288%). The investigated flavonoids showed no significant larvicidal effect. The pronounced larvicidal effect of S. pseudoquina bark crude extract and its fractions on S. frugiperda indicates that this plant presents an insecticidal potential to be explored in integrated pest management programs.

show abstract

Section: Introductionmentioning

confidence: 99%