In China women uphold half of the sky, but only a quarter of them received reperfusion therapy for acute coronary syndrome

Evaluation of Carotid Plaque Neovascularization in Patients With Coronary Heart Disease on Contrast‐Enhanced Ultrasonography

“…Contrast‐enhanced US has been used to detect neovascularization in carotid plaques. Initial studies have shown that qualitative assessments of plaque neovascularization, as detected with contrast‐enhanced US, correlate with histologically determined microvascular density and to plaque echogenicity, the latter being a marker of plaque vulnerability . Similarly, quantitative data on plaque neovascularization obtained by maximum intensity projection methods have been shown to correlate with histologic neovascularization and inflammatory cell infiltration.…”

“…Vulnerable coronary plaques are closely related to ACS, and carotid atherosclerostic plaques have a similar pathologic basis as coronary plaques. Neovascularization in plaques was identified after studies concerning its major characteristic of plaque instability and its status as an independent predictor of ACS, eventually resulting in plaque rupture and hemorrhage, with a close correlation with the occurrence of clinical cardiovascular events . Detecting the correlation between the degree of plaque enhancement and the density of neovascularization in plaques by contrast‐enhanced US can provide rating information for the risk of carotid plaques.…”

“…Neovascularization in plaques was identified after studies concerning its major characteristic of plaque instability and its status as an independent predictor of ACS, eventually resulting in plaque rupture and hemorrhage, with a close correlation with the occurrence of clinical cardiovascular events. 23,24 Detecting the correlation between the degree of plaque enhancement and the density of neovascularization in plaques by contrast-enhanced US can provide rating information for the risk of carotid plaques. Contrast-enhanced US can highlight neovascularization within carotid plaques and provide qualitative and quantitative assessments of plaque vulnerability in real time, compensating for the shortcomings of conventional examination methods.…”

“…Initial studies have shown that qualitative assessments of plaque neovascularization, as detected with contrast-enhanced US, correlate with histologically determined microvascular density and to plaque echogenicity, the latter being a marker of plaque vulnerability. 17,[20][21][22][23] Similarly, quantitative data on plaque neovascularization obtained by maximum intensity projection methods have been shown to correlate with histologic neovascularization and inflammatory cell infiltration. As one of the most sensitive and specific indicators of the state of chronic inflammation, high-sensitivity CRP is involved in the formation and development of carotid neovascularization in patients with CHD and is suitable as an important determinant of neovascularization.…”

The importance of China (and Tsung O Cheng, International Consulting Editor for China) to the International Journal of Cardiology

“…Writing on topics ranging from as diverse as sexual activity and coronary arterial disease [5], the use of unexplained acronyms in specialty journals [6], deciphering Chinese names [7], history of cardiology in China [8,9] and the profession [10], to contemporary social and political issues [11][12][13][14] and to some extremely highly cited reviews, [15] he has always been a strong and loyal supporter of the journal [16].…”