2008
DOI: 10.3201/eid1409080952
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In Memoriam: Michael B. Gregg (1930–2008)

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“…In general, the viruses, bacteria, and parasites for which new vaccines are needed are either complex in their pathogenesis, exhibit extensive variability, or have evolved evasive mechanisms to bypass the immune system. The development of vaccines for many pathogens remains elusive, and there is a growing requirement for the fast development of effective vaccines for emerging diseases (Morens et al, 2008). Here, we discuss the technological advances that are propelling into a new era in vaccinology, highlighting the various aspects which remain the target of development, for combating the challenges of emerging infectious and non-infectious diseases.…”
Section: Introductionmentioning
confidence: 99%
“…In general, the viruses, bacteria, and parasites for which new vaccines are needed are either complex in their pathogenesis, exhibit extensive variability, or have evolved evasive mechanisms to bypass the immune system. The development of vaccines for many pathogens remains elusive, and there is a growing requirement for the fast development of effective vaccines for emerging diseases (Morens et al, 2008). Here, we discuss the technological advances that are propelling into a new era in vaccinology, highlighting the various aspects which remain the target of development, for combating the challenges of emerging infectious and non-infectious diseases.…”
Section: Introductionmentioning
confidence: 99%