In restless legs syndrome, during changes in vigilance, the forced EEG shifts from alpha activity to delta or high alpha may lead to the altered states of dopamine receptor function and the symptoms

Akpinar, S; Aydin, Hamdullah; Kutukcu, Yasar

doi:10.1016/j.mehy.2006.12.027

Cited by 6 publications

(4 citation statements)

References 27 publications

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“…Eighteen healthy participants (eight females) were included in this study (mean age = 23.5 years, SD = 2.7), after one participant with restless legs syndrome was excluded (Akpinar et al 2007 ). The inclusion criteria were as follows: age 18–45 years, willingness to participate, willing to provide written informed consent, right-handedness, German (or Swiss German) language as mother tongue, normal or corrected to normal vision, and luteal phase for women.…”

Section: Methodsmentioning

confidence: 99%

Effect of Acoustic fMRI-Scanner Noise on the Human Resting State

Grieder

Koenig

2022

Brain Topogr

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Our knowledge about the human resting state is predominantly based on either electroencephalographic (EEG) or functional magnetic resonance imaging (fMRI) methods. While EEG recordings can be performed in seated posture in quiet conditions, the fMRI environment presents a substantial contrast with supine and restricted posture in a narrow tube that is filled with acoustic scanner noise (ASN) at a chainsaw-like volume level. However, the influence of these diverging conditions on resting-state brain activation is neither well studied nor broadly discussed. In order to promote data as a source of sharper hypotheses for future studies, we investigated alterations in EEG-frequency-band power (delta, theta, alpha, beta, gamma) and spatial power distribution as well as cortical vigilance measures in different postures and ASN surroundings over the course of time. Participants (N = 18) underwent three consecutive resting-state EEG recordings with a fixed posture and ASN setting sequence; seated, supine, and supine with ASN (supnoise) using an MRI simulator. The results showed that compared to seated, supnoise, the last instance within the posture sequence, was characterized by lower power and altered spatial power distribution in all assessed frequency bands. This might also have been an effect of time alone. In delta, theta, alpha, and beta, the power of supnoise was also reduced compared to supine, as well as the corresponding distribution maps. The vigilance analysis revealed that in supine and supnoise, the highest and lowest vigilance stages were more dominant compared to the seated and earliest posture condition within the sequence. Hence, our results demonstrate that the differences in recording settings and progress of time are related to changes in cortical arousal and vigilance regulation, findings that should be taken into account more profoundly for hypothesis generation as well as analytic strategies in future resting-state studies.

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Section: Methodsmentioning

confidence: 99%

Effect of Acoustic fMRI-Scanner Noise on the Human Resting State

Grieder

Koenig

2022

Brain Topogr

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“…Pretpostavljena je disfunkcija dopaminergičkog sistema, na nivou strijatalnih i/ili spinalnih dopaminskih receptora, i A11 grupe neurona lokalizovanih u hipotalamusu, kao integralnog dela sistema. Ovi neuroni modulišu spinalnu ekscitabilnost, čije alteracije utiču na senzorno procesiranje, predominantno aferentnih vlakana za donje ekstremitete, u strukturama moždanog stabla [26,27].…”

Section: Patofiziologija Rls-aunclassified

The modern treatment of the restless legs syndrome: Diagnostic and therapeutic options

Stamenović¹,

Djuric²,

Djuric³

et al. 2014

Engrami

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“…DRSIS of the dopamine receptors at the DSDS neurons may occur either due to antipsychotic medications as in NIA or due to loss of alpha activity gate control in case of RLS. In both instances the result is a deficiency in dopamine transmission at the DSDS (15).…”

Section: Introductionmentioning

confidence: 98%