In-situ characterization of porcine fibroblasts in response to silver ions by Raman spectroscopy and liquid scanning transmission electron microscopy

Zhao, Yuanfeng; Zhang, Wei; Devener, Brian Van; Bunch, Thomas D.; Zhou, Anhong; Isom, S. Clay

doi:10.1016/j.talanta.2022.123522

Cited by 3 publications

(2 citation statements)

References 67 publications

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“…AlphaFold can utilize deep learning techniques to predict the interactions between metal ions and major proteins through molecular docking simulations [ 198 ]. In addition, the localization and movement of metal ions within cells can be tracked through artificial intelligence (AI) comparison [ 199 ], fluorescence probes [ 200 ] or electron microscopy [ 201 ]. Moreover, the metabolic process of metal ions in the body can also be tracked through isotopes [ 202 ].…”

Section: Conclusion and Future Prospectivementioning

confidence: 99%

Exogeneous metal ions as therapeutic agents in cardiovascular disease and their delivery strategies

Hong,

Tian,

Zhu

et al. 2023

Regenerative Biomaterials

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Metal ions participate in many metabolic processes in the human body, and their homeostasis is crucial for life. In cardiovascular diseases (CVDs), the equilibriums of metal ions are frequently interrupted, which are related with a variety of disturbances of physiological processes leading to abnormal cardiac functions. Exogenous supplement of metal ions has the potential to work as therapeutic strategies for the treatment of CVDs. Compared with other therapeutic drugs, metal ions possess broad availability, good stability and safety, and diverse drug delivery strategies. The delivery strategies of metal ions are important to exert their therapeutic effects and reduce the potential toxic side effects for cardiovascular applications, which are also receiving increasing attentions. Controllable local delivery strategies for metal ions based on various biomaterials are constantly being designed. In this review, we comprehensively summarized the positive roles of metal ions in the treatment of CVDs from three aspects: protecting cells from oxidative stress, inducing angiogenesis, and adjusting the functions of ion-channels. In addition, we introduced the transferability of metal ions in vascular reconstruction and cardiac tissue repair, as well as the currently available engineered strategies for the precise delivery of metal ions, such as integrated with nanoparticles, hydrogels, and scaffolds.

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Section: Conclusion and Future Prospectivementioning

confidence: 99%

Exogeneous metal ions as therapeutic agents in cardiovascular disease and their delivery strategies

Hong,

Tian,

Zhu

et al. 2023

Regenerative Biomaterials

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show abstract

“…1 Therefore, it is very important to monitor Ag + ions in the environment. Traditional detection approaches, such as atomic absorption spectrometry (AAS), 2 inductively coupled plasma mass spectrometry (ICP-MS), 3,4 uorescence spectrometry, 5,6 etc., have the characteristics of expensive equipment, high cost and complex sample pretreatment, so it is still a great challenge to build easy-to-operate sensors. Compared with these methods, photoelectrochemical (PEC) measurement is a simple and effective analytical method for detecting Ag + ion concentration.…”

Section: Introductionmentioning

confidence: 99%

A label-free photoelectrochemical biosensor for silver ions based on Zn–Co doped C and CdS QD nanomaterials

Zhang,

Wang,

Zhou

et al. 2024

Anal. Methods

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Characterization of biodiversity and meat quality in Guizhou yellow cattle: Correlations among intrinsic factors

Zhou,

Zhao,

Jiang

et al. 2024

Journal of Food Composition and Analysis

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In-situ characterization of porcine fibroblasts in response to silver ions by Raman spectroscopy and liquid scanning transmission electron microscopy

Cited by 3 publications

References 67 publications

Exogeneous metal ions as therapeutic agents in cardiovascular disease and their delivery strategies

Exogeneous metal ions as therapeutic agents in cardiovascular disease and their delivery strategies

A label-free photoelectrochemical biosensor for silver ions based on Zn–Co doped C and CdS QD nanomaterials

Characterization of biodiversity and meat quality in Guizhou yellow cattle: Correlations among intrinsic factors

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