In situ endoluminal brushing: a safe technique for the diagnosis of catheter-related bloodstream infection

Dobbins, Brian; Kite, P.; Catton, James; Wilcox, Mark H.; McMahon, Michael

doi:10.1016/j.jhin.2004.06.025

Cited by 21 publications

(8 citation statements)

References 17 publications

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“…The same authors reported sensitivity, specificity and positive predictive values of 75.5%, 69.1% and 79.3%, respectively, with a threshold value of > 100 CFU ⁄ mL cultured from one lumen. Special tools for collecting in-situ cultures from the small lumen of a paediatric CVAD with a protected brush may be available in the near future [96].…”

Section: E T H O D S T O C O N F I R M T H E D I a G N O S I S W I mentioning

confidence: 99%

Diagnosis and treatment of catheter-related infections in paediatric oncology: an update

Simon

Bode

Beutel

2006

Clinical Microbiology and Infection

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Otherwise unexplained clinical signs of infection in patients with long-term tunnelled or totally implanted central venous access devices (CVADs) are suspected to be CVAD-associated. Diagnostic methods include catheter swabs, blood cultures and cultures of the catheter tip or port reservoir. In the case of a suspected CVAD-related bloodstream infection in paediatric oncology patients, in-situ treatment without prompt removal of the device can be attempted. Removal of the CVAD should be considered if bacteraemia persists or relapses > or = 72 h after the initiation of (in-vitro effective) antibacterial therapy administered through the line. Timely removal of the device is also recommended if the patient suffers from a complicated infection, or if Staphylococcus aureus, Pseudomonas aeruginosa, multiresistant Acinetobacter baumannii or Candida spp. are isolated from blood cultures. Duration of therapy depends on the immunological recovery of the patient, the pathogen isolated and the presence of related complications, such as thrombosis, pneumonia, endocarditis and osteomyelitis. Antibiotic lock techniques in addition to systemic treatment are beneficial for Gram-positive infections. Although prospectively controlled studies are lacking, the concomitant use of urokinase locks and taurolidine secondary prophylaxis seem to favour catheter salvage.

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Section: E T H O D S T O C O N F I R M T H E D I a G N O S I S W I mentioning

confidence: 99%

Diagnosis and treatment of catheter-related infections in paediatric oncology: an update

Simon

Bode

Beutel

2006

Clinical Microbiology and Infection

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“…Endoluminal brushing is a technique initially developed to sample the endoluminal surface of the catheter (44,45) and confirm a diagnosis of catheter-related bacteremia. Its use was later expanded in a small sample to determine the effect on patency (46) by passing through the entire length of the catheter from hub to tip and removing the fibrous connective tissue from the intraluminal surface.…”

Section: Bedside Management Of Catheter Dysfunctionmentioning

confidence: 99%

Interventional Nephrology

Niyyar

Chan

2013

Clinical Journal of the American Society of Nephrology

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SummaryDespite recommendations by various national guidelines advocating arteriovenous fistulae as the access of choice in patients undergoing hemodialysis (HD), the use of central venous catheters (CVCs) remains widespread among both incident and prevalent HD patients. Unfortunately, long-term use of CVCs is fraught with complications, which are a major cause of morbidity and death in this patient population. Complications include a high rate of infections, as well as thrombus and sheath-related mechanical dysfunction. This review addresses prevention and management of noninfectious catheter-related dysfunction.

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“…Bacteria counts from both peripheral blood culture and catheter were reduced after brushing perhaps due to removal of intraluminal biomass (B). (97) There are limitations to the use of simultaneous peripheral blood and catheter cultures without quantification. Most catheters are colonized on their connections and in their lumen.…”

Section: Do the Different Forms Of Diagnosing Catheter Related Associmentioning

confidence: 99%

Diretrizes para tratamento da sepse grave/choque séptico: abordagem do agente infeccioso - diagnóstico

Diament¹,

Salomão²,

Rigatto³

et al. 2011

Rev. bras. ter. intensiva

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In situ endoluminal brushing: a safe technique for the diagnosis of catheter-related bloodstream infection

Cited by 21 publications

References 17 publications

Diagnosis and treatment of catheter-related infections in paediatric oncology: an update

Diagnosis and treatment of catheter-related infections in paediatric oncology: an update

Interventional Nephrology

Diretrizes para tratamento da sepse grave/choque séptico: abordagem do agente infeccioso - diagnóstico

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