In situ generated PtNPs to enhance electrochemiluminescence of multifunctional nanoreactor COP T4VTP6 for AFB1 detection

Lv, Xiaoyi; Tan, Fei; Miao, Tian; Cui, Bo; Zhang, Jianguo; Fang, Yishan; Shen, Yizhong

doi:10.1016/j.foodchem.2022.134002

Cited by 18 publications

(5 citation statements)

References 23 publications

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“…Therefore, ECL technology represents an optimal analytical instrument for the identification of trace toxins in foodstuffs, the environment, and the diagnosis of disease, etc. Depending on the types of sensing elements employed, ECL biosensors can be categorized into three groups, namely those based on antibodies [ 70 , 71 , 72 ], aptamers [ 73 , 74 , 75 ], as well as molecular imprinting polymers (MIPs) [ 76 , 77 , 78 ]. The development of these types of detectors is the focus of the rest of this paper.…”

Section: Mycotoxin Detection Techniques Based On Biosensorsmentioning

confidence: 99%

Application of Biosensors for the Detection of Mycotoxins for the Improvement of Food Safety

Szelenberger,

Cichoń,

Zajaczkowski

et al. 2024

Toxins

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Mycotoxins, secondary metabolites synthesized by various filamentous fungi genera such as Aspergillus, Penicillium, Fusarium, Claviceps, and Alternaria, are potent toxic compounds. Their production is contingent upon specific environmental conditions during fungal growth. Arising as byproducts of fungal metabolic processes, mycotoxins exhibit significant toxicity, posing risks of acute or chronic health complications. Recognized as highly hazardous food contaminants, mycotoxins present a pervasive threat throughout the agricultural and food processing continuum, from plant cultivation to post-harvest stages. The imperative to adhere to principles of good agricultural and industrial practice is underscored to mitigate the risk of mycotoxin contamination in food production. In the domain of food safety, the rapid and efficient detection of mycotoxins holds paramount significance. This paper delineates conventional and commercial methodologies for mycotoxin detection in ensuring food safety, encompassing techniques like liquid chromatography, immunoassays, and test strips, with a significant emphasis on the role of electrochemiluminescence (ECL) biosensors, which are known for their high sensitivity and specificity. These are categorized into antibody-, and aptamer-based, as well as molecular imprinting methods. This paper examines the latest advancements in biosensors for mycotoxin testing, with a particular focus on their amplification strategies and operating mechanisms.

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Section: Mycotoxin Detection Techniques Based On Biosensorsmentioning

confidence: 99%

Application of Biosensors for the Detection of Mycotoxins for the Improvement of Food Safety

Szelenberger,

Cichoń,

Zajaczkowski

et al. 2024

Toxins

View full text Add to dashboard Cite

show abstract

“…Owing to these merits, ECL technology has become one of the most suitable analytical tools for trace target detection in food, environment, disease diagnosis, and so on. According to the recognition elements used, the ECL biosensors could be divided into three categories, including antibodies [ 54 , 55 , 56 , 57 , 58 , 59 ], aptamers [ 27 , 60 , 61 , 62 , 63 ], and molecular imprinting polymer (MIP) [ 26 , 64 , 65 , 66 ].…”

Section: Sensing Strategies In Electrochemiluminescence (Ecl) Biosens...mentioning

confidence: 99%

“…biosensors could be divided into three categories, including antibodies [54][55][56][57][58][59], aptamers [27,[60][61][62][63], and molecular imprinting polymer (MIP) [26,[64][65][66].…”

Section: Sensing Strategies In Electrochemiluminescence (Ecl) Biosens...mentioning

confidence: 99%

Recent Advances in Electrochemiluminescence Biosensors for Mycotoxin Assay

et al. 2023

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Rapid and efficient detection of mycotoxins is of great significance in the field of food safety. In this review, several traditional and commercial detection methods are introduced, such as high-performance liquid chromatography (HPLC), liquid chromatography/mass spectrometry (LC/MS), enzyme-linked immunosorbent assay (ELISA), test strips, etc. Electrochemiluminescence (ECL) biosensors have the advantages of high sensitivity and specificity. The use of ECL biosensors for mycotoxins detection has attracted great attention. According to the recognition mechanisms, ECL biosensors are mainly divided into antibody-based, aptamer-based, and molecular imprinting techniques. In this review, we focus on the recent effects towards the designation of diverse ECL biosensors in mycotoxins assay, mainly including their amplification strategies and working mechanism.

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“…Electrochemiluminescence (ECL), a neoteric light emission driven by electrochemical stimulation in the vicinity of the electrode, , presenting the merits of high sensitivity, simplified operation, and excellent controllability, has been widely used in diverse applications, most notably in light-emitting devices, − imaging microscopy, − as well as fields of food analysis, − environment monitoring, − and clinical diseases diagnosis. , To give increased impetus for the evolution of ECL applications, exploitation of high-performing ECL emitters as one crucial stepping stone plays a pivotal role. Compared with classical ECL emitters (Ru(bpy) 3 2+ , luminol, etc .…”

Section: Introductionmentioning

confidence: 99%

Ligand-Based Shielding Effect Induced Efficient Near-Infrared Electrochemiluminescence of Gold Nanoclusters and Its Sensing Application

et al. 2023

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Preparing high-efficiency ECL gold nanoclusters (Au NCs) still faces a serious challenge due to the poor stability of co-reactant radicals in aqueous media. Herein, we report a ligand-based shielding effect induced record near-infrared (λ max = 786 nm) ECL efficiency of β-cyclodextrin-protected Au NCs (β-CD-Au NCs) with triethylamine (TEA) as co-reactant. The ligand of β-CD-Au NCs with a matched hydrophobic cavity could encapsulate TEA driven by host−guest chemistry, which not only allows the generation of TEA • in the cavity to diminish environmental exposure, thus reducing the quenching by dissolved oxygen, water, etc., but also shortens the charge transfer pathway without extensive chemical modification. Density functional theory, 1 H NMR spectra, electron paramagnetic resonance, and differential pulse voltammetry studies revealed that the β-CD ligand-based shielding effect significantly increased the reactivity efficiency of TEA. More importantly, in stark contrast to those of traditional ligand-protected Au NCs, the ECL efficiency of β-CD-Au NCs enhanced 321-fold versus BSA-Au NCs, 153-fold versus ATT-Au NCs, and 19-fold versus GSH-Au NCs with 1 mM TEA. Therefore, this work provides an in-depth understanding of the crucial role of ligands in enhancing the active co-reactant radical stability for highefficiency ECL metal NCs to immensely stimulate their promising applications. Using the β-CD-Au NCs as emitters, a "signal off" ECL sensing platform was constructed to detect noradrenaline as a model target with a lower detection limit of 0.91 nM.

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In situ generated PtNPs to enhance electrochemiluminescence of multifunctional nanoreactor COP T4VTP6 for AFB1 detection

Cited by 18 publications

References 23 publications

Application of Biosensors for the Detection of Mycotoxins for the Improvement of Food Safety

Application of Biosensors for the Detection of Mycotoxins for the Improvement of Food Safety

Recent Advances in Electrochemiluminescence Biosensors for Mycotoxin Assay

Ligand-Based Shielding Effect Induced Efficient Near-Infrared Electrochemiluminescence of Gold Nanoclusters and Its Sensing Application

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