Jupiter's moon Ganymede is the largest moon in the solar system and the only moon with its own intrinsic, permanent magnetic field that extends far beyond its surface to form a magnetosphere (Gurnett et al., 1996;Kivelson et al., 1996Kivelson et al., , 2002. The first missions to investigate Ganymede in detail were the Voyager flybys of Jupiter in 1979, and the Galileo mission, which orbited Jupiter from 1995 to 2003 and executed a series of six close Ganymede flybys (summarized by Volwerk et al., 2022). Key findings of these missions, combined with Earth-based observations from facilities such as Hubble and ALMA, are as follows.Ganymede has a fully differentiated interior including a metallic core (Anderson et al., 1996; Hussmann et al., 2022). A subsurface liquid salt-water ocean forms a global layer, the top of which can be no more than 330 km below the icy surface (Kivelson et al., 1999;Saur et al., 2015Saur et al., , 2018. Ganymede is slightly larger and denser than, and forms a class with, the two other large solar system moons Callisto and Saturn's Titan. However, Ganymede's complex geologic history, which includes tectonic and/or volcanic production of grooved terrain well after the moon's formation, cutting through ancient heavily cratered terrain, shows a very different formation and evolution history than the other large moons (Schenk et al., 2022).Ganymede's neutral molecular oxygen exosphere (Hall et al., 1998), sourced from sputtering, radiolysis, and sublimation of surface ice, is ionized by photo-ionization and electron impact on open field lines. O, H, and H 2 O have also been detected (