2016
DOI: 10.5505/ejm.2016.76476
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In Stored Human Blood, The Inhibitor Effect of Tannic Acid and Caffeic Acid on Lipid Peroxidation and Oxidative DNA Damage

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Cited by 5 publications
(12 citation statements)
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References 19 publications
(25 reference statements)
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“…Because of a possible increase in 8-OHDG levels in stored blood can cause gene mutations and false protein coding after blood transfusion, it is important to prevent injury in the DNA bases. Increasing oxidative stress and decreasing antioxidant capacity due to storage time (3,9,15,17,26), especially OH . radicals, can lead to DNA oxidation by damaging nuclear proteins and DNA (9).…”
Section: Discussionmentioning
confidence: 99%
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“…Because of a possible increase in 8-OHDG levels in stored blood can cause gene mutations and false protein coding after blood transfusion, it is important to prevent injury in the DNA bases. Increasing oxidative stress and decreasing antioxidant capacity due to storage time (3,9,15,17,26), especially OH . radicals, can lead to DNA oxidation by damaging nuclear proteins and DNA (9).…”
Section: Discussionmentioning
confidence: 99%
“…A total of 60 µg/mL resveratrol and 60 µg/mL serotonin was added to the second and third group, respectively. For blood storage time and measurement intervals, time intervals specified by previous studies were selected (15,17,26). For this purpose, MDA and oxidized CoQ10 were measured in the samples taken at the beginning, 7, 14, 21 and 28 days in all groups.…”
Section: Establishment Of Groups and Measurement Intervalsmentioning
confidence: 99%
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“…Another marker of oxidative stress is ubiquinone 10 (CoQ10), which is a lipid structured compound of the mammalian mitochondrial electron chain that prevents damage caused by biomolecules and lipid peroxidation by playing a role in the production of active forms of ascorbic acid and tocopherol (9,16). CoQ10 is important for cardiac muscle function, and it plays a role as an antioxidant in cardiac disorders and heart failures.…”
mentioning
confidence: 99%
“…CoQ10 is important for cardiac muscle function, and it plays a role as an antioxidant in cardiac disorders and heart failures. CoQ10 is a strong antioxidant that protects cellular structure by eliminating free radicals (9,16,18). 8-hydroxy-2-deoxyguanosine (8-OHdG) is the most abundant marker of oxidative DNA damage.…”
mentioning
confidence: 99%