This article addresses the consumption of over-the-counter medications and the risks associated with the consumption of medications without medical authorization by 3rd grade high school students at a public school in São Sebastião -AL. The research aimed to identify the practice of self-medication in high school students, show the risks associated with it and promote visibility about the rational use of medication. The work was developed in a State High School, located in São Sebastião, Alagoas, from April to May 2021. For data collection, it was used: the application of an online questionnaire, lectures, availability of infographic relating the theme to the contents of the school curriculum and production of explanatory pamphlets about the theme. The information obtained was analyzed and grouped into graphs, tables and figures, for a better visualization of the results. After performing the four steps, it can be seen the practice of self-medication by these students, with a prevalence of consumption among female participants, with the drugs most used without prescription being Paracetamol, Dipyrone and Dorflex. It was also possible to observe the influence of family and friends for the implementation of this practice and the need for greater awareness of these. As an intervention, pamphlets were produced and posted by the students in digital media.