In‐vitro activity of ceftiofur against Australian isolates of the family <i>Pasteurellaceae</i> associated with respiratory disease in cattle and pigs

Blackall, P. J.; Pahoff, J.L.; Stephens, C.P.; Darvill, F.M.

doi:10.1111/j.1751-0813.1996.tb13739.x

Cited by 10 publications

(6 citation statements)

References 6 publications

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“…This ®nding is in good agreement with those of Gutie Ârrez Martin and Rodrõ Âguez Ferri (1993), Hewett (1994), Raemdonck et al (1994), Watts et al (1994), Salmon et al (1995) and Blackall et al (1996). Aspoxicillin, developed for the treatment of pneumonic pasteurellosis of cattle and pigs in Japan, was found to exhibit the same excellent activity against penicillin-susceptible isolates as ceftiofur.…”

Section: Discussionsupporting

confidence: 86%

Antimicrobial Susceptibility of Pasteurella multocida Isolated From Cattle and Pigs

Yoshimura¹,

Ishimaru²,

Endoh³

et al. 2001

J Vet Med Series B

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Minimum inhibitory concentrations (MICs) of 10 antimicrobial agents were determined for Pasteurella multocida from cattle and pigs (72 and 68 isolates, respectively). Higher MICs were observed with oxytetracycline, doxycycline, tilmicosin and thiamphenicol for porcine isolates than for bovine isolates. Enrofloxacin was the most active, with an MIC for 90% of the isolates (MIC90) of 0.05 microg/ml for both bovine and porcine isolates. Aspoxicillin exhibited the same excellent activity against penicillin-susceptible isolates as ceftiofur, with MICs ranging from < or = 0.025 to 0.1 microg/ml. Aminoglycosides were less active, with an MIC90 of > 100 microg/ml for both bovine and porcine isolates.

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Section: Discussionsupporting

confidence: 86%

Antimicrobial Susceptibility of Pasteurella multocida Isolated From Cattle and Pigs

Yoshimura¹,

Ishimaru²,

Endoh³

et al. 2001

J Vet Med Series B

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“…Among the antimicrobial agents were ceftiofur and enro¯oxacin that were highly active against P. multocida. This ®nding is in good agreement with those of Gutie Ârrez Martin and Rodrõ Âguez Ferri (1993), Hewett (1994), Raemdonck et al (1994), Watts et al (1994), Salmon et al (1995) and Blackall et al (1996). Aspoxicillin, developed for the treatment of pneumonic pasteurellosis of cattle and pigs in Japan, was found to exhibit the same excellent activity against penicillin-susceptible isolates as ceftiofur.…”

Section: Discussionsupporting

confidence: 85%

Antimicrobial Susceptibility of Pasteurella multocida Isolated From Cattle and Pigs

Yoshimura¹,

Ishimaru²,

Endoh³

et al. 2001

Journal of Veterinary Medicine, Series B

View full text Add to dashboard Cite

Minimum inhibitory concentrations (MICs) of 10 antimicrobial agents were determined for Pasteurella multocida from cattle and pigs (72 and 68 isolates, respectively). Higher MICs were observed with oxytetracycline, doxycycline, tilmicosin and thiamphenicol for porcine isolates than for bovine isolates. Enro¯oxacin was the most active, with an MIC for 90 % of the isolates (MIC 90 ) of 0.05 lg/ml for both bovine and porcine isolates. Aspoxicillin exhibited the same excellent activity against penicillin-susceptible isolates as ceftiofur, with MICs ranging from £ 0.025 to 0.1 lg/ml. Aminoglycosides were less active, with an MIC 90 of > 100 lg/ml for both bovine and porcine isolates.

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“…They reported that ceftiofur sodium exerts bactericidal effect on tested microorganisms at concentration equal to or at most one doubling dilution above MIC. Many authors were reportedthat high activity of ceftiofur against P. multocida isolated from cattle, swine and duck in vitro [10,12,28,29]. Also, some authors [8] reported that the MIC of ceftiofur sodium required to inhibit growth of 90% of isolates of E. coli, Pasteurella spp., Klebsiella spp., and beta-haemolytic Streptococci was <0.5 microg/ml, and intravenous administration of ceftiofur sodium at rate of 5 mg/kg every 12 h would provide sufficient coverage for the treatment of susceptible bacterial isolates.…”

Section: Discussionmentioning

confidence: 99%

Studies on the Antibacterial Activity of Ceftiofur Sodium in Vitro and Birds

Alkheraije¹

2013

OJVM

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This study was carried out to evaluate the antibacterial activity of ceftiofur sodium as anti-infective chemotherapeutic agent belonged to the third generation of cephalosporins against different bacterial pathogens in vitro and birds. The obtained results showed that it was more effective and superior in its action than that the other compared antibacterial agents. The disc diffusion test revealed that most P. multocida isolates were highly sensitive to ceftiofur sodium with minimum inhibitory concentrations (MICs) ranging between 0.625 -2.5 μg/ml and minimal bactericidal concentration (MBCs) equal or two folds of the MICs.Seventy Hubbard chicks of 20 days old with average 200 gm body weight were divided into three groups each of

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In‐vitro activity of ceftiofur against Australian isolates of the family Pasteurellaceae associated with respiratory disease in cattle and pigs

Cited by 10 publications

References 6 publications

Antimicrobial Susceptibility of Pasteurella multocida Isolated From Cattle and Pigs

Antimicrobial Susceptibility of Pasteurella multocida Isolated From Cattle and Pigs

Antimicrobial Susceptibility of Pasteurella multocida Isolated From Cattle and Pigs

Studies on the Antibacterial Activity of Ceftiofur Sodium in Vitro and Birds

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