IN VITRO ANALYSIS OF COMPOUND A FORMATION BY SEVOFLURANE IN A COMPUTER CONTROLLED CLOSED CIRCUIT PHYSIOFLEX[registered sign] ANESTHESIA APPARATUS

Rolly, G; Versichelen, L; Bouche, Marie-Paule; Bocxlaer, Jan Van; Struys, Michel; Herten, C. Van Der; Leenheer, A. De

doi:10.1097/00000539-199902001-00192

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“…In general, the results of this study cannot be transferred to different settings at fresh gas flows of 0.5 L min −1 with different anaesthetic ventilator systems. Data obtained with a Physioflex ® system (a closed circuit anaesthesia machine) resulted in lower compound A concentration compared with our data obtained in the present study [15–17]. The circuit gases in the Physioflex ® are circulated unidirectionally by a blower at a rate of 70 L min −1 , which effectively reduces the temperature in the absorber thus resulting in a reduction in compound A concentration.…”

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confidence: 61%