In-vitro and in-vivo Sunscreen Activity of Active Compounds Isolated from Fruits of Phaleria marcocarpha (Scheff.) Boerl

Eff, Aprilita Rina Yanti; Pertiwi, Ratih Dyah; Rakhmawati, Irvani; Utami, Tyas Putri

doi:10.5530/jyp.2018.2s.21

Cited by 8 publications

(2 citation statements)

References 8 publications

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“…UV B light induces sunburn (burning skin), at high and long exposure induces skin cancer formation. Even though UV A amount reaches to earth is 10% more than UV B, more erythema production is caused by UV B [22]. Substances can provide a protective effect as a sunscreen if its SPF value is >2 [23].…”

Section: Discussionmentioning

confidence: 99%

Photoprotective and Inhibitory Activity of Tyrosinase in Extract and Fractions of Terminalia catappa L.

Indrisari

Sartini

Miskad

et al. 2021

Open Access Maced J Med Sci

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BACKGROUND: Chronic exposure to ultraviolet (UV) radiation causes various skin damages. One of the most significant risks to skin occurrence is cancer and photoaging. Recent strategies for photoprotection have included incorporating natural sunscreens and antityrosinase. AIM: This study aimed to determine the sun protection factor (SPF) and inhibitory activity of tyrosinase of the extract and fractions of leaves of Terminalia catappa Linn. METHOD: The dried leaves were macerated with 96% ethanol and fractionated using n-hexane, ethyl acetate, and water. The extract and fractions were screened for their phytochemical profile, and tyrosinase inhibitory activity was evaluated and expressed as IC50. The photoprotective activity of extract and fractions were measured by a UV spectrophotometric. RESULTS: Among the tested samples, the ethyl acetate fraction showed ultraprotection on erythema transmission rate (%TE), sunblock on pigmentation transmission (%TP), and minimum protection on SPF. Ethyl acetate fraction showed the highest activity to inhibit tyrosinase (IC50 was 50.54±2.37 μg/mL). The phytochemical analysis of ethyl acetate fraction revealed the presence of phenolic and flavonoid compounds. CONCLUSION: This study’s findings revealed a higher tyrosinase inhibitor and sun protection capacity of ethyl acetate fraction of leaves of T. catappa and suitable to develop as a cosmetic agent.

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Section: Discussionmentioning

confidence: 99%

Photoprotective and Inhibitory Activity of Tyrosinase in Extract and Fractions of Terminalia catappa L.

Indrisari

Sartini

Miskad

et al. 2021

Open Access Maced J Med Sci

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“…Sunscreen is a substance or material that can protect the skin against ultra violet (UV) radiation's harmful effects by absorbing, diffusing, or reflecting the rays, reducing the energy that affects the skin (Eff et al, 2018;Latha et al, 2013). Cosmetic preparation that contains sunscreen is usually labeled with a specific Sun Protection Factor (SPF) strength.…”

Section: Introductionmentioning

confidence: 99%

Potential of Frangipani (Plumeria alba) Leaves Extract as Ultra Violet Protection

2020

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Sunlight is the source of life and energy. Besides that, sunlight also creates skin challenges such as sunburn, pigmentation, wrinkles, dermatitis, aging, and skin cancer. Natural sunscreen protection is a popular and preferred way among various regions of the world to reduce sunlight's harmful effect. This study aimed to determine the potential of frangipani (Plumeria alba) leaves extract in some concentrations as ultraviolet protection. Plumeria alba extract contained secondary metabolites such as flavonoids, phenolics, and alkaloids that function as impeding ultraviolet radiation. This study used an experimental method consisting of four treatments and six replications. This study shows that the extract with concentration 2500; 5000; 7500; and 10000 ppm consecutively have SPF value of 6.24; 12.00; 18.45; and 22.64. It can be concluded the P. alba leaves extract potential as ultraviolet protection.

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Synthesis and characterization of metal soap (Zn-, Al-, and Mg-soap) from sunflower oil and its potential as sunscreen

Sutrisno

Wijaya

Sukarianingsih

et al. 2021

4th International Seminar on Chemistry

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In-vitro and in-vivo Sunscreen Activity of Active Compounds Isolated from Fruits of Phaleria marcocarpha (Scheff.) Boerl

Cited by 8 publications

References 8 publications

Photoprotective and Inhibitory Activity of Tyrosinase in Extract and Fractions of Terminalia catappa L.

Photoprotective and Inhibitory Activity of Tyrosinase in Extract and Fractions of Terminalia catappa L.

Potential of Frangipani (Plumeria alba) Leaves Extract as Ultra Violet Protection

Synthesis and characterization of metal soap (Zn-, Al-, and Mg-soap) from sunflower oil and its potential as sunscreen

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