In vitro anticancer effects of insect tea in TCA8113 cells

Qian, Yu; Li, Gui-Jie; Wang, Rui; Zhou, Yalin; Sun, Peng

doi:10.4103/0973-1482.137979

Cited by 6 publications

(2 citation statements)

References 29 publications

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“…This was likewise the case for human liver cancer cells evaluated last year 172 . Anti-inflammatory activity was also evidenced through the down regulation of genes encoding nuclear factor kappa-light-chain-enhancer of activated B cells (NF κ B), inducible nitric oxide synthase (iNOS), and COX-2 171 . Furthermore, insect tea was found to be as effective at preventing gastric ulcers as the gastric ulcer drug, ranitidine and buccal mucosa cancer preventative effects in in vivo murine models173, 174.…”

Section: Lepidoptera (Butterflies and Moths)mentioning

confidence: 70%

“…Additional efforts in the past two years have been made to validate new therapeutic properties of insect tea. In a study on human tongue carcinoma cells, insect tea significantly induced apoptosis in cancer cells by upregulating BAX, CASP3, CASP9 and down regulating BCL2 171 . This was likewise the case for human liver cancer cells evaluated last year 172 .…”

Section: Lepidoptera (Butterflies and Moths)mentioning

confidence: 75%

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Insects: an underrepresented resource for the discovery of biologically active natural products

Seabrooks¹,

Hu²

2017

Acta Pharmaceutica Sinica B

111

123

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Nature has been the source of life-changing and -saving medications for centuries. Aspirin, penicillin and morphine are prime examples of Nature׳s gifts to medicine. These discoveries catalyzed the field of natural product drug discovery which has mostly focused on plants. However, insects have more than twice the number of species and entomotherapy has been in practice for as long as and often in conjunction with medicinal plants and is an important alternative to modern medicine in many parts of the world. Herein, an overview of current traditional medicinal applications of insects and characterization of isolated biologically active molecules starting from approximately 2010 is presented. Insect natural products reviewed were isolated from ants, bees, wasps, beetles, cockroaches, termites, flies, true bugs, moths and more. Biological activities of these natural products from insects include antimicrobial, antifungal, antiviral, anticancer, antioxidant, anti-inflammatory and immunomodulatory effects.

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Section: Lepidoptera (Butterflies and Moths)mentioning

confidence: 70%

Section: Lepidoptera (Butterflies and Moths)mentioning

confidence: 75%

Insects: an underrepresented resource for the discovery of biologically active natural products

Seabrooks¹,

Hu²

2017

Acta Pharmaceutica Sinica B

111

123

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Insect tea extract attenuates CCl4-induced hepatic damage through its antioxidant capacities in ICR mice

Liao¹,

Zou

Wang

2016

Food Sci Biotechnol

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The Insect tea extract (ITE) contained many polyphenols, the aim of the present study was to determine the preventive effects of ITE on CCl-induced hepatic damage in mice. ITE treated mice could reduce hepatic injury compared to the control mice. The 200 mg/kg ITE increased TC, ALB, SOD, CAT, GSH-Px serum levels, and decreased ALT, AST, ALP, TG, BUN, NO, MDA levels compared to the control group. By histological observation, ITE reduced injury to hepatic cells, and these effects were close to that seen with the drug silymarin. The antioxidant related mRNA and protein expressions of Mn SOD, Gu/Zn SOD, CAT, and GSH-Px increased with ITE treatment in hepatic damage mice. ITE treated mice also showed higher IκB-α mRNA and protein expression, and lower NF-κB-p65, iNOS, COX-2 expressions than those of control mice. These results proved ITE has a prophylactic effect in protecting against hepatic injury through the antioxidant capacities.

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Insect tea originated from ethnic minority regions in Southwest China: A review on the types, traditional uses, nutrients, chemistry and pharmacological activities

Wang

2023

Journal of Ethnopharmacology

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In vitro anticancer effects of insect tea in TCA8113 cells

Abstract: The results showed that Insect tea has good in vitro anticancer effects in TCA8113 cells, like green tea.

Cited by 6 publications

References 29 publications

Insects: an underrepresented resource for the discovery of biologically active natural products

Insects: an underrepresented resource for the discovery of biologically active natural products

Insect tea extract attenuates CCl4-induced hepatic damage through its antioxidant capacities in ICR mice

Insect tea originated from ethnic minority regions in Southwest China: A review on the types, traditional uses, nutrients, chemistry and pharmacological activities

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