In vitro antifungal activity of the tea tree (Melaleuca alternifolia) essential oil and its major components against plant pathogens

Terzi, Valeria; Morcia, Caterina; Faccioli, Primetta; Valè, Giampiero; Tacconi, G.; Malnati, Mauro S.

doi:10.1111/j.1472-765x.2007.02128.x

Cited by 119 publications

(88 citation statements)

References 23 publications

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“…The main component of A. zerumbet was 1,8-cineol, which has previously been shown to have antibacterial activity (CHA et al, 2007), antifungal activity (TERZI et al, 2007) and activity against the nematode Anisakis simplex (NAVARRO et al, 2008). The main component of L. camara was caryophyllene oxide, an antifungal agent (YANG et al, 1999) that has analgesic and anti-inflammatory activity (CHAVAN et al, 2010).…”

Section: Discussionmentioning

confidence: 99%

In vitro effects of Coriandrum sativum, Tagetes minuta, Alpinia zerumbet and Lantana camara essential oils on Haemonchus contortus

Macedo

Oliveira

Camurça-Vasconcelos

et al. 2013

Rev. Bras. Parasitol. Vet.

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In vitro effects of AbstractPhytotherapy can be an alternative for the control of gastrointestinal parasites of small ruminants. This study evaluated the efficacy of Alpinia zerumbet, Coriandrum sativum, Tagetes minuta and Lantana camara essential oils by two in vitro assays on Haemonchus contortus, an egg hatch test (EHT) and larval development test (LDT). No effect was observed for L. camara in the EHT. A. zerumbet, C. sativum and T. minuta essential oils exhibited a dose-dependent effect in the EHT, inhibiting 81.2, 99 and 98.1% of H. contortus larvae hatching, respectively, at a concentration of 2.5 mg mL -1 . The effective concentration to inhibit 50% (EC50) of egg hatching was 0.94, 0.63 and 0.53 mg mL -1 for A. zerumbet, C. sativum and T. minuta essential oils, respectively. In LDT, L. camara, A. zerumbet, C. sativum and T. minuta at concentration of 10 mg mL -1 inhibited 54.9, 94.2, 97.8 and 99.5% of H. contortus larval development, presenting EC50 values of 6.32, 3.88, 2.89 and 1.67 mg mL -1 , respectively. Based on the promising results presented in this in vitro model, it may be possible use of these essential oils to control gastrointestinal nematodes. However, their anthelmintic activity should be confirmed in vivo.Keywords: Phytotherapy, anthelmintic, gastrointestinal nematodes. ResumoFitoterapia pode ser uma alternativa para o controle de parasitas gastrintestinais de pequenos ruminantes. Este estudo avaliou a eficácia dos óleos essenciais de Alpinia zerumbet, Coriandrum sativum, Tagetes minuta e Lantana camara sobre Haemonchus contortus através de dois testes in vitro, teste de eclosão dos ovos (TEO) e teste de desenvolvimento larval (TDL). Nenhum efeito foi observado para L. camara no TEO. Os óleos essenciais de A. zerumbet, C. sativum e T. minuta exibiram um efeito dose dependente no TEO inibindo a eclosão das larvas de H. contortus em 81,2, 99 e 98,1%, respectivamente, na concentração de 2,5 mg mL -1 . A concentração efetiva para inibir 50% (CE50) da eclosão dos ovos foi de 0,94, 0,63 e 0,53 mg mL -1 para os óleos essenciais de A. zerumbet, C. sativum e T. minuta, respectivamente. No TDL, 10 mg mL -1 de L. camara, A. zerumbet, C. sativum e T. minuta inibiram em 54,9, 94,2, 97,8 e 99,5% do desenvolvimento larvar, apresentando valores de CE50 de 6,32, 3,88, 2,89 e 1,67 mg mL -1 , respectivamente. Com base nos resultados promissores apresentados neste modelo in vitro, pode ser possível a utilização destes óleos essenciais para controlar os nematoides gastrintestinais. No entanto, a sua atividade anti-helmíntica deve ser confirmada in vivo.Palavras-chave: Fitoterapia, anti-helmínticos, nematoides gastrintestinais.

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Section: Discussionmentioning

confidence: 99%

In vitro effects of Coriandrum sativum, Tagetes minuta, Alpinia zerumbet and Lantana camara essential oils on Haemonchus contortus

Macedo

Oliveira

Camurça-Vasconcelos

et al. 2013

Rev. Bras. Parasitol. Vet.

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“…This oil is largely employed for its antimicrobial properties due to the compound terpinen-4-ol. It is incorporated as the active ingredient in many topical formulations used to treat infections (Carson et al, 2006) and as alternative natural fungicide (Terzi et al, 2007). Niaouli oil is extracted from M. viridiflora (also known as Melaleuca quinquenervia).…”

Section: Introductionmentioning

confidence: 99%

In vitro antibacterial effect of exotic plants essential oils on the honeybee pathogen Paenibacillus larvae, causal agent of American foulbrood

Fuselli

Rosa

Eguaras

et al. 2010

Span. j. agric. res.

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Chemical composition and antimicrobial activity of exotic plants essential oils to potentially control Paenibacillus larvae, the causal agent of American foulbrood disease (AFB) were determined. AFB represents one of the main plagues that affect the colonies of honeybees Apis mellifera L. with high negative impact on beekeepers worldwide. Essential oils tested were niaouli (Melaleuca viridiflora) and tea tree (Melaleuca alternifolia) from Myrtaceae, and citronella grass (Cymbopogon nardus) and palmarosa (Cymbopogon martinii) from Gramineae. The components of the essential oils were identified by SPME-GC/MS analysis. The antimicrobial activity of the oils against P. larvae was determined by the broth microdilution method. In vitro assays of M. viridiflora and C. nardus oils showed the inhibition of the bacterial strains at the lowest concentrations tested, with minimal inhibitory concentration (MIC) mean value about 320 mg L -1 for both oils, respectively. This property could be attributed to the kind and percentage of the components of the oils. Terpinen-4-ol (29.09%), α-pinene (21.63%) and limonene (17.4%) were predominant in M. viridiflora, while limonene (24.74%), citronelal (24.61%) and geraniol (15.79%) were the bulk of C. nardus. The use of these essential oils contributes to the screening of alternative natural compounds to control AFB in the apiaries; toxicological risks and other undesirable effects would be avoided as resistance factors, developed by the indiscriminate use of antibiotics.Additional key words: antimicrobial activity, chemical composition, Cymbopogon martini, Cymbopogon nardus, Melaleuca alternifolia, Melaleuca viridiflora, honeybees' pathogen. ResumenActividad antibacteriana in vitro de los aceites esenciales de plantas exóticas frente al patógeno bacteriano Paenibacillus larvae, agente causal de loque americana en colonias de abejas melíferas Se determinó la composición química y se evaluó la actividad antimicrobiana in vitro de cuatro aceites esenciales de plantas exóticas para el control del patógeno bacteriano Paenibacillus larvae, agente causal de loque americana, que afecta a los estadios de larva y pupa de la abeja melífera (Apis mellifera L.). Esta enfermedad produce grandes pérdidas económicas en la apicultura mundial. Los aceites esenciales analizados, pertenecientes a la familia Myrtaceae y Gramineae, fueron: niaouli (Melaleuca viridiflora) y árbol del té (Melaleuca alternifolia), citronela (Cymbopogon nardus) y palmarosa (Cymbopogon martinii), respectivamente. La composición química de los aceites esenciales se efectuó por cromatografía de gases acoplada a un espectrómetro de masas (CG-EM). La concentración inhibitoria mínima (MIC) se determinó por el método de microdilución en caldo y la concentración bactericida mínima (MBC) en agar MYPGP. Los aceites esenciales de niaoulí y citronela registraron valores promedio de MIC de 320 mg L -1 , atribuidos al tipo y porcentaje de sus componentes: terpinen-4-ol (29,09%), α-pineno (21,63%) y limoneno (17,4%) que predominaron ...

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“…T-4-ol ve α-terpineol bu bağlamda en etkin iki kimyevi içerik olarak karşımıza çıkmaktadır. 57 Aynı zamanda T-4-ol ve α-terpineol'un yapısındaki hidroksil grupları orta derecede suda çözünebilir olma özelliği kazandır-maktadır. Böylece bu maddeler su ile hücreye girer, hücre membranının stabilizasyonunu bozmaktadır ve olay akışı osmotik şok ile sonuçlanmaktadır.…”

Section: çAy Ağaci Yaği(tea Tree Oġl)unclassified

Di̇ş Heki̇mli̇ği̇nde Kullanilan Bazi Bi̇tki̇leri̇n Anti̇bakteri̇yal Ve Anti̇fungal Etki̇leri̇

Ercan¹,

Gülal²

2015

Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi

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Oral diseases, including dental caries, periodontal disease, and tooth loss, affect the majority of the population and can affect a person's overall health. Nature plays an important role as a source of new antibacterial and antifungal substances that can be used in the prevention of caries and fungal infection. Many antibacterial agents have been developed against dental caries. However, they lack the qualities of an ideal agent. Thus presently, antibacterial activity of herbal agents is being extensively studied. Plants have been used for centuries to improve dental health and to promote oral hygiene. Antibacterial and antifungal effects of some plants have been proved as well. This review discusses chemical composition and usage of these plants as well as their influence on oral health with pearls and pitfulls.

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In vitro antifungal activity of the tea tree (Melaleuca alternifolia) essential oil and its major components against plant pathogens

Cited by 119 publications

References 23 publications

In vitro effects of Coriandrum sativum, Tagetes minuta, Alpinia zerumbet and Lantana camara essential oils on Haemonchus contortus

In vitro effects of Coriandrum sativum, Tagetes minuta, Alpinia zerumbet and Lantana camara essential oils on Haemonchus contortus

In vitro antibacterial effect of exotic plants essential oils on the honeybee pathogen Paenibacillus larvae, causal agent of American foulbrood

Di̇ş Heki̇mli̇ği̇nde Kullanilan Bazi Bi̇tki̇leri̇n Anti̇bakteri̇yal Ve Anti̇fungal Etki̇leri̇

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