In vitro antimicrobial activity of six Ethiopian medicinal plants against Staphylococcus aureus, Escherichia coli and Candida albicans

Gishen, Nigus Zegeye; Taddese, Solomon; Zenebe, Tizazu; Dires, Kassahun; Tedla, Abebe; Mengiste, Berhan; Shenkute, Demissew; Tesema, Alemnesh; Shiferaw, Yoseph; Lulekal, Ermias

doi:10.1016/j.eujim.2020.101121

Cited by 22 publications

(5 citation statements)

References 28 publications

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“…Peppermint ( Mentha piperita L.) EO, which was mainly characterized by menthol and menthone, showed significant levels of antibacterial activity against Staphylococcus aureus , Micrococcus flavus , Bacillus subtilis , Salmonella enteritidis , and Staphylococcus epidermidis [ 56 ]. Furthermore, peppermint EO was active against Escherichia coli [ 47 ].…”

Section: Antimicrobial Activities Of Essential Oilsmentioning

confidence: 99%

Antibacterial, Antifungal, Antimycotoxigenic, and Antioxidant Activities of Essential Oils: An Updated Review

et al. 2020

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The interest in using natural antimicrobials instead of chemical preservatives in food products has been increasing in recent years. In regard to this, essential oils—natural and liquid secondary plant metabolites—are gaining importance for their use in the protection of foods, since they are accepted as safe and healthy. Although research studies indicate that the antibacterial and antioxidant activities of essential oils (EOs) are more common compared to other biological activities, specific concerns have led scientists to investigate the areas that are still in need of research. To the best of our knowledge, there is no review paper in which antifungal and especially antimycotoxigenic effects are compiled. Further, the low stability of essential oils under environmental conditions such as temperature and light has forced scientists to develop and use recent approaches such as encapsulation, coating, use in edible films, etc. This review provides an overview of the current literature on essential oils mainly on antifungal and antimycotoxigenic but also their antibacterial and antioxidant activities. Additionally, the recent applications of EOs including encapsulation, edible coatings, and active packaging are outlined.

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Section: Antimicrobial Activities Of Essential Oilsmentioning

confidence: 99%

Antibacterial, Antifungal, Antimycotoxigenic, and Antioxidant Activities of Essential Oils: An Updated Review

et al. 2020

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“…It has been suggested in [19].that a decrease in pH inside the cell is responsible for C. zeylanicum's inhibitory action [19]. That a decrease in pH inside the cell is responsible for C. zeylanicum's inhibitory action [20].…”

Section: Pics : Shows Inhibition Zone Produced By Present Plant Extra...mentioning

confidence: 99%

Effect of Cinnamomum zeylanicum Bark Extracts on Clinically Important Drug Resistant Pathogenic Bacteria

M. Nassa,

Kamel Al-Moussaw,

Khalid Yaseen

et al. 2023

JEPS

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Background: Cinnamomum Zeylanicum, is one of the oldest herbal medicines and a popular spice crop used in Asian countries. It has been valued for centuries for its distinct flavor and aroma, and it also possesses various medicinal properties. In Cinnamomum Zeylanicum, there are many constituents such as cimmaldehyde, eugenol, linalool and cinnamic acid. Therapeutic compounds found in plants are gaining attention as a potential source for new drug development. Objectives : The study aims to identify potential novel treatments for bacterial infections by evaluating commercially available ethanolic extracts' in vitro antimicrobial activity and observing their effects on bacterial biological activity inhibition. Material and methods: The well diffusion method was used to examine the in vitro antimicrobial activity of an ethanol extract of Cinnamomum zeylanicum bark against both gram-positive (S. aureus and S.epidermides) and gram-negative (E. coli and P. aeruginosa) standard microbes. In this study, all pathogenic bacteria that affect humans tested were inhibited to varying degrees by the concentrations investigated. Results:The results indicate that the inhibition zone for gram positive bacteria is greater than that of gram negative bacteria at all concentrations, ranging from 19.22 (29%)mm to 18.44 (28%)mm against S. aureus and S. epidermids. The inhibition zones for E. coli and P. aeruginosa are 14.67 (22%) and 14.11 (21%) respectively. Conclusion: In this study, all pathogenic bacteria that affect humans were inhibited to varying degrees by the concentrations investigated.

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“…In folkloric medicines, C. citratus is used to aid digestion, weight loss as well as in the treatment of headache, malaria, hypertension, respiratory disorders and skin irritations (21)(22)(23)(24). Leaves of C. citratus have been used for oral hygiene, management of menstrual disorders and as flavor enhancer in food and cosmetics (25)(26)(27). Other notable medicinal properties of C. citratus include: anti-carcinogenic (28), antibacterial (29), antiprotozoal (30), antifungal (31), anti-inflammatory (32)(33)(34), antioxidant (35), cardioprotective (36), antidiabetic (37,38) and anti-HIV (39).…”

Section: Introductionmentioning

confidence: 99%

Cymbopogon citratus Leaf Extract Mitigates Hepatorenal Injury in Carbon Tetrachloride and Rifampicin-Exposed Rats

Ogunmoyole

2024

Curr. Trends Biotechnol. Pharm.

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The rising trend in the global burden of liver and kidney diseases calls for concern. The present study therefore investigates the medicinal potentials of C. citratus in rat model of hepatorenal toxicity. Forty male albino rats were randomly grouped and exposed to carbon tetrachloride (3 ml/kg bw.) and rifampicin (250 mg/kg bw.) toxicity and post-treated with C. citratus leaf extract and silymarin (100 mg/kg bw) as standard drug according to experimental design. Specific biomarkers such as aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), catalase (CAT), superoxide dismutase (SOD), reduced glutathione (GSH), urea, uric acid, total bilirubin, total protein (TP) as well as lipid profile were determined. Exposure to toxicants caused a marked decrease in antioxidant enzymes and high-density lipoprotein (HDL) with concomitant increase in triglyceride, total cholesterol and low-density lipoprotein (LDL). Levels of AST, ALT, ALP, total bilirubin, urea and uric acid were markedly increased in animals exposed to toxicants without post treatment with the extract. Post-administration of C. citratus leaf extract caused a decrease in AST, ALT and ALP, TC, TG and LDL-c while there was significant increase in the level of HDL and antioxidant enzyme relative to the untreated group. Effect of C. citratus was comparable to the reference drug, silymarin (100 mg/kg) at the same dose.The study showed the medicinal potentials of C. citratus as revealed in both biochemical and histopathogical parameters. Hence, it is a choice candidate that can be exploited in the treatment of liver and kidney diseases.

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In vitro antimicrobial activity of six Ethiopian medicinal plants against Staphylococcus aureus, Escherichia coli and Candida albicans

Cited by 22 publications

References 28 publications

Antibacterial, Antifungal, Antimycotoxigenic, and Antioxidant Activities of Essential Oils: An Updated Review

Antibacterial, Antifungal, Antimycotoxigenic, and Antioxidant Activities of Essential Oils: An Updated Review

Effect of Cinnamomum zeylanicum Bark Extracts on Clinically Important Drug Resistant Pathogenic Bacteria

Cymbopogon citratus Leaf Extract Mitigates Hepatorenal Injury in Carbon Tetrachloride and Rifampicin-Exposed Rats

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