In-vitro antioxidant and oxidant properties of Centaurea rigida

The objective of this study is to evaluate the antioxidant, antiulcer, anti-inflammatory and analgesic activity of the aqueous extract of Angelica archangelica L., a medicinal plant of the traditional pharmacopoeia of Algeria. The aqueous extract showed a large amount of total polyphenols, tannins, chlorophyll a, b, carotenoids and a small amount of flavonoids with values of 80.16±14.3 mg EAG/g of extract, 3.12±2.01 mg EQ/g of extract, 226.10±4.50 mg EAT/g of extract, 6.10±50.62, 12.00±31.53 and 1.78±0.40 μg/mL respectively. In addition, the aqueous extract of A. archangelica showed a high ability to trap DPPH radical in with IC50 at 16.9±2.03μg/mL. However, the aqueous extract has a great protective effect against β-carotene degradation at 91.98±0.64% after 24 hours and significant ferrous ion chelation activity at46.2 ±1.53µg/mL. Furthermore, the anti-inflammatory activity was studied according to the protein denaturation inhibition method and, according to the results obtained, the extract of A. archangelica at concentrations of 250, 500 μg/mL and 1 mg/mL have ahigh antiinflammatory activity whose inhibition percentages are 78.85±5.31%, 86.65±2.70% and 89.89±0.58% respectively. The analgesic effect of the aqueous extract of A. archangelica, showed that the concentration 400 mg/mL has a greet abdominal cramps inhibitory effect in comparison with the concentration 200 mg/mL with a percentage of 98.28%. The antiulcer effect of the aqueous extract of A. archangelica was evaluated by the 70% ethanol-induced ulcer test. The results obtained reveal that the aqueous extract 200 and 400 mg/mL exerted a considerable effect of protecting the stomach at 86.55±3.51% and 82.82±2.18% respectively.

Section: Introductionmentioning

confidence: 99%

Phytochemical Screening, Antioxidant, Antiulcer, Anti-Inflammatory and Analgesic Activity of the Aqueous Extract of Angelica archangelica

Mamache

BENSLAMA

Benchikh

et al. 2022

“…The role of free radicals in many disease conditions has been well established. Several biochemical reactions in our body generate reactive oxygen species and these are capable of damaging crucial bio-molecules (Kına et al, 2021). If they are not effectively scavenged by cellular constituents, they lead to disease conditions (Halliwell et al 1995).…”

Section: Introductionmentioning

confidence: 99%

Free Radical Scavenging, Metal chelating and Antiperoxidative Activities of M. communis Berries Methanol extract and its Fractions

Benchikh

Benabdallah

Amira

et al. 2022

Oxidative stress resulted from free radicals and reactive oxygen species (ROS) are associated with many diseases. Phytotherapy has known a great evolution all the world and some medicinal plants are important remedies of some diseases. Myrtle (Mrytus communis L.) is a plant of Myrtaceae family which is common in the Mediterranean region, with flowering, always green leaves and fruit. This study aims to investigate in vitro antioxidant capacity of Myrtus communis berries methanol extract and its three fractions using five assays: ABTS scavenging radicals, metal chelating, hydrogen peroxide and inhibition of lipid peroxidation assays. EAE extract possessed the highest antioxidant activity in ABTS (EAE (IC50=2.5 µg/ml ) and lipid peroxidation models (90.17%). Whereas, AqE is the most active extract in metal chelating activity (IC50=0.73±0.03 mg/ml) and H2O2 assay. These results support the traditional use of this plant in healthcare and it could be a new source of antioxidant natural drugs.

“…Fruits and vegetables are rich in functional components such as minerals and bioactive phytochemicals. Increased intake of fresh fruits and vegetables is linked to a lower risk of contracting major degenerative diseases such as cancer, cataracts, diabetes, Alzheimer and Parkinson disease (Ilahy et al, 2011;Tlili et al, 2011;Liu., 2013;Tomé-Carneiro and Visioli., 2016;Sevindik et al, 2017;Kına et al, 2021;Uysal et al, 2021). Watermelon is now widely regarded as a "functional food" and popular fruit that contains key nutritional and bioactive elements that provide a variety of health advantages.…”

Section: Introductionmentioning

confidence: 99%

Effect of The Storage Period on the Antioxidant Properties of Different Watermelon Cultivars Grown in Tunisia

Tlili

Ilahy²,

Rached

et al. 2022

Postharvest storage conditions frequently affect nutritional quality of fruits and vegetables. Temperature and storage duration are the most important factors to extend shelf life and maintain quality of fresh watermelon. This study was conducted to determine the changes in the antioxidant properties of watermelon during storage. Fruits of the watermelon cultivars were harvested and stored at 5ºC for a period of 15 days. During storage antioxidant contents (lycopene and total phenolics) and total antioxidant activity were evaluated. The objective of this work was to determine the content of the antioxidant properties in different watermelon genotypes at four different postharvest storage periods (0, 5, 10 and 15 days). Furthermore, the nutritional quality is strongly influenced by the storage period. The cv Mahdia was the most suitable for extended storage periods.