In Vitro Antioxidant Studies of Lagerstroemia speciosa Leaves

Pareek, Anil; Suthar, Manish; Rathore, Garvendra S; Bansal, V. K.; Kumawat, Tarachand

doi:10.1016/s0975-3575(10)80109-9

Cited by 9 publications

(3 citation statements)

References 11 publications

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“…Aerial parts of the plant have inhibitory activities against nitric oxide production (Choi et al, 2015). In another study, leaves of this plant demonstrated significant antioxidant activities in vitro (Pareek et al, 2010). The major chemical constituents of the leaves are ellagic acid, ellagitannins, caffeic acid and corosolic acid (Bai et al, 2008).…”

Section: Resultsmentioning

confidence: 96%

Standardized method to extract phenolic compounds from Lagerstroemia speciosa L. (Jarul) for enhanced antioxidant activity

Bajpai¹,

Madhusudan

Sibi³

2021

JANS

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Phenolic compounds contribute to the antioxidant property of plants and the efficient extraction of plant phenolics could enhance its antioxidant potential. Lagerstroemia speciosa (L.) Pers. has been investigated for its pharmacological activities, but comparing its antioxidant activities of phenolics derived from its various parts has a key role in developing natural antioxidants. This study was conducted to standardize the extraction of phenolics from leaves, pods and branches of L. speciosa plant, followed by determination of antioxidant activities of their solvent fractions. Phenolic compounds were extracted from the leaves, pods and branches under different parameters such as temperature, pH, type of solvent and volume of the solvent. The extracted phenolic compounds were subjected to solvent fractions and antioxidant assays were performed. Among the various extraction methods tested, the best method was 50% ethanol +1% HCl, refluxing temperature, 100 ml of solvent and 1 hour extraction time. The best solvent fractions were determined as NaHCO3 + ethyl acetate for pods and ethyl acetate alone for leaves and branches with extracted phenolics content of 150.2 mg/g, 136.2 mg/g and 82.9 mg/g, respectively. The chloroform fraction was best among the fractions with maximum ascorbic acid equivalent (ASE) in all the parts of L. speciosa tested. Ferrous ion chelating capacity indicated that butanol fraction had the highest chelation and the same was recorded in ferric ion chelating assay with an EC50 value of 28.2. Hydroxyl radical scavenging activity of the fractions indicated that NaHCO3 + EtOAc fraction of pods had potential activity. Thus, the phenolic compounds from L. speciosa are excellent sources for future investigation on potent natural antioxidant compounds.

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Section: Resultsmentioning

confidence: 96%

Standardized method to extract phenolic compounds from Lagerstroemia speciosa L. (Jarul) for enhanced antioxidant activity

Bajpai¹,

Madhusudan

Sibi³

2021

JANS

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“…The ability of extracts to scavenge hydrogen peroxide was determined according to the method of Ruch et al 21 with slight modifications 22 . A solution of hydrogen peroxide (20 mM) was prepared in phosphate buffer (pH 7.4).…”

Section: Hydrogen Peroxide Scavenging Activitymentioning

confidence: 99%

In Vitro Antioxidative Profiling of Different Extracts of Fagonia Schweinfurthii (Hadidi) Hadidi

Pareek¹,

Nagori²

2013

Int. J. Res. Ayurveda Pharm.

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The present study was aimed to evaluate in vitro antioxidant activity of Fagonia schweinfurthii (Hadidi) Hadidi. F. schweinfurthii was successively extracted with different solvents such as petroleum ether, chloroform, ethyl acetate and methanol. The antioxidant activity of F. schweinfurthii extracts was investigated using different assays like 2,2-diphenyl-1-picryl hydrazyl (DPPH) radical scavenging activity, 2,2'-azino-bis(3ethylbenzthiazoline-6-sulfonic acid) (ABTS) diammonium salt radical scavenging activity, hydrogen peroxide (H2O2) scavenging activity, nitric oxide (NO) scavenging activity, ferric reducing power and β-carotene bleaching assay. Total phenolic and flavonoid contents of the extracts were determined by using Folin-Ciocalteu method and aluminium chloride method, respectively in order to evaluate a relationship between the antioxidant activity and the phytochemical constituents. The F. schweinfurthii methanolic extract (FSME) exhibited significantly (p < 0.05) higher ABTS radical, NO radical and H2O2 scavenging activity, reducing power ability and inhibition of β-carotene bleaching. Total phenol and flavonoid contents were highest in the FSME (94.61 ± 1.51 mg GAE/g and 21.52 ± 0.17 mg QE/g) respectively. The present study showed that FSME had more antioxidant power than other extracts. Further studies are necessary to isolate active principles responsible for the overall antioxidant activity of the extracts.

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“…The plant L. speciosa, commonly known as "Jarul", belongs to the Lythraceae family [9]. These plant parts are containing various phytocomponents such as alkaloids, terpenoids, flavonoids and others [10,11]. Further, its leaf and flower extract has been widely studied for green synthesis of Ag NPs [8] and studied for various biological activities, such as antibacterial, anti-diabetic and anti-inflammatory activities [12,13].…”

Section: Introductionmentioning

confidence: 99%

Antibacterial, Antioxidant, Larvicidal and Anticancer Activities of Silver Nanoparticles Synthesized Using Extracts from Fruits of Lagerstroemia speciose and Flowers of Couroupita guianensis

et al. 2022

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The present study aimed to analyze the in vitro antibacterial, antioxidant, larvicidal and cytotoxicity properties of green synthesized silver nanoparticles (Ag NPs) using aqueous extracts from fruits of Lagerstroemia speciosa and flowers of Couropita guinensis. Synthesized Ag NPs were characterized using UV-DRS, FTIR, XRD, DLS, and High-Resolution SEM and TEM analyses. Absorption wavelength was observed at 386 nm by UV-DRS analysis and energy band gap was calculated as 3.24 eV. FTIR analysis showed the existence of various functional groups in the aqueous extract and in the NPs. DLS analysis showed the stability and particle size of the synthesized Ag NPs. SEM analysis revealed that Ag NPs are in a face centered cubic symmetry and spherical shape with a size of 23.9 nm. TEM analysis showed particle size as 29.90 nm. Ag NPs showed antibacterial activity against both Gram-positive and Gram-negative bacteria. DPPH scavenging trait of Ag NPs was ranging from 20.0 ± 0.2% to 62.4 ± 0.3% and observed significant larvicidal activity (LC50 at 0.742 ppm and LC90 at 6.061 ppm) against Culex quinquefasciatus. In vitro cytotoxicity activity of Ag NPs was also tested against human breast cancer (MCF-7) and fibroblast cells (L-929) and found that cells viabilities are ranging (500 to 25 µg/mL) from 52.5 ± 0.4 to 94.0 ± 0.7% and 53.6 ± 0.5 to 90.1 ± 0.8%, respectively. The synthesized Ag NPs have the potential to be used in the various biomedical applications.

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In Vitro Antioxidant Studies of Lagerstroemia speciosa Leaves

Cited by 9 publications

References 11 publications

Standardized method to extract phenolic compounds from Lagerstroemia speciosa L. (Jarul) for enhanced antioxidant activity

Standardized method to extract phenolic compounds from Lagerstroemia speciosa L. (Jarul) for enhanced antioxidant activity

In Vitro Antioxidative Profiling of Different Extracts of Fagonia Schweinfurthii (Hadidi) Hadidi

Antibacterial, Antioxidant, Larvicidal and Anticancer Activities of Silver Nanoparticles Synthesized Using Extracts from Fruits of Lagerstroemia speciose and Flowers of Couroupita guianensis

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