In vitro biocompatibility of vapour phase polymerised conductive scaffolds for cell lines

Choi, Jong Seob; Park, Jin Seul; Kim, Boram; Lee, Byong‐Taek; Yim, Jin‐Heong

doi:10.1016/j.polymer.2017.07.047

Cited by 26 publications

(38 citation statements)

References 20 publications

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“…SEM analysis was employed to monitor cells' attachment and morphology on the hybrid scaffolds [68][69][70]. The produced scaffolds supported the attachment and in vitro proliferation of the cultured osteoblasts.…”

Section: Sem Analysis-cell Morphology Evaluationmentioning

confidence: 99%

Mechanical Enhancement of Cytocompatible 3D Scaffolds, Consisting of Hydroxyapatite Nanocrystals and Natural Biomolecules, Through Physical Cross-Linking

et al. 2020

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Bioinspired scaffolds mimicking natural bone-tissue properties holds great promise in tissue engineering applications towards bone regeneration. Within this work, a way to reinforce mechanical behavior of bioinspired bone scaffolds was examined by applying a physical crosslinking method. Scaffolds consisted of hydroxyapatite nanocrystals, biomimetically synthesized in the presence of collagen and l-arginine. Scaffolds were characterized by X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy (SEM), microcomputed tomography, and nanoindentation. Results revealed scaffolds with bone-like nanostructure and composition, thus an inherent enhanced cytocompatibility. Evaluation of porosity proved the development of interconnected porous network with bimodal pore size distribution. Mechanical reinforcement was achieved through physical crosslinking with riboflavin irradiation, and nanoindentation tests indicated that within the experimental conditions of 45% humidity and 37 °C, photo-crosslinking led to an increase in the scaffold’s mechanical properties. Elastic modulus and hardness were augmented, and specifically elastic modulus values were doubled, approaching equivalent values of trabecular bone. Cytocompatibility of the scaffolds was assessed using MG63 human osteosarcoma cells. Cell viability was evaluated by double staining and MTT assay, while attachment and morphology were investigated by SEM. The results suggested that scaffolds provided a cell friendly environment with high levels of viability, thus supporting cell attachment, spreading and proliferation.

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Section: Sem Analysis-cell Morphology Evaluationmentioning

confidence: 99%

Mechanical Enhancement of Cytocompatible 3D Scaffolds, Consisting of Hydroxyapatite Nanocrystals and Natural Biomolecules, Through Physical Cross-Linking

et al. 2020

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“…Polystirene (PS) and poly(lactic-co-glycolic acid) (PLGA) are the polymers used for this role. 7,31 Afterwards, both template microspheres can be selectively removed by the addition DCM.…”

Section: Porous Scaffoldsmentioning

confidence: 99%

3D Scaffolds Based on Conductive Polymers for Biomedical Applications

2018

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“…18,19 최근에는 본 연구진은 기 상중합을 이용한 유-무기 하이브리드 소재를 연구하여 오고 있다. [20][21][22][23][24][25][26] (Figure 1(a)). GO 수용액에 천연 고분자인 SCC를 1 wt% 첨가하여 동결주조하자 균일한 표면을 가지는 구형입 자를 만들 수 있었다 (Figure 1(b (Figure 3(c), (f), (i)).…”

Section: 폴리머 제42권 제3호 2018년unclassified

“…복잡한 형상을 가진 다양한 피착체에 코팅이 용이 하다 24,25,[27][28][29]. 특히, PPy는 PEDOT에 비해 단량체 비용이 낮 고, 합성이 용이하며, 전도성을 조절할 수 있고, 가역적인 산 화 환원에서 전기 변색 작용을 하며, 환경 안정성 때문에 유 망한 전도성 고분자 중 하나로 간주되어 왔다.…”

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Preparation of Graphene Aerogel-Polypyrrole Conductive Composite by Using Simultaneous Co-vaporized Vapor Phase Polymerization

Fernandez¹,

Ko²,

Yim³

2018

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In this study, we fabricated spherical reduced graphene oxide aerogels (rGOA) through freeze casting and thermal reduction for the fabrication of carbon-conducting polymer (polypyrrole, PPy) composites with excellent electrical/ mechanical properties. The rGOA-PPy or rGOA-PPy-SiO 2 composites were prepared by a simultaneous co-vaporized vapor phase polymerization (SC-VPP) process. The surface area of the rGOA-PPy-SiO 2 composites prepared using the SC-VPP process was expected to be larger than that of the rGOA-PPy composites, because the surface of the rGOA-PPy-SiO 2 composites was entirely curved and the open pores were exposed on the surface. The orientation of pore structure was well developed. In addition, the surface area of the particle increased due to the open pores on the surface of the rGOA-PPy-SiO 2 composite, thereby widening the contact area with the electrode, resulting in showing improved specificcapacitance over rGOA or rGOA-PPy composite.

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In vitro biocompatibility of vapour phase polymerised conductive scaffolds for cell lines

Cited by 26 publications

References 20 publications

Mechanical Enhancement of Cytocompatible 3D Scaffolds, Consisting of Hydroxyapatite Nanocrystals and Natural Biomolecules, Through Physical Cross-Linking

Mechanical Enhancement of Cytocompatible 3D Scaffolds, Consisting of Hydroxyapatite Nanocrystals and Natural Biomolecules, Through Physical Cross-Linking

3D Scaffolds Based on Conductive Polymers for Biomedical Applications

Preparation of Graphene Aerogel-Polypyrrole Conductive Composite by Using Simultaneous Co-vaporized Vapor Phase Polymerization

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