In-vitro Comparison of Antibacterial (Triclosan) Coated  Suture Material with Non-coated Suture Material against common  Bacterial pathogens Causing Surgical Site Infection

Soumya, Swaminathan; Maste, Praful; Hogade, Sumati A

doi:10.20546/ijcmas.2017.612.356

Cited by 2 publications

(5 citation statements)

References 11 publications

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“…The effectiveness of coated sutures has been analyzed in the past by calculating the ZOI around the suture material placed on agar plates coated with saliva,[ 17 ] by counting colony-forming units after exposing the coated suture to strains of Staphylococcus aureus , Staphylococcus epidermidis , and Escherichia coli ,[ 18 ] and using scanning electron microscopy or confocal laser scanning microscopy. [ 18 ]…”

Section: Discussionmentioning

confidence: 99%

“…In addition, we evaluated the ZOI in terms of the area by superimposing a graph sheet (millimeter markings) onto the agar plates and measuring the total number of squares covered by the inhibition zone. [ 17 ] This method provided a more accurate measurement of the ZOI in terms of area compared to previous studies, which evaluated the inhibition diameters by making wells in agar plates inoculated with bacteria. [ 16 ]…”

Section: Discussionmentioning

confidence: 99%

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A comparative assessment of antibacterial properties of neem oil coated sutures: An in vitro study

Kaur,

Sekhar,

Sharma

et al. 2023

Journal of Indian Society of Periodontology

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Background: When it comes to surgical site infection (SSI), it has been shown that two-thirds of wound infections starts around the incision line and the number is even greater in the presence of sutures. Therefore, a number of compounds have been used to coat the suture materials which tend to decrease the SSI some of which include ciprofloxacin, Aloe vera, and chlorhexidine. Objective: The objective of this study was to assess the antibacterial properties of neem oil-coated sutures in anaerobic culture media when compared to triclosan-coated sutures and uncoated sutures. Materials and Methods: The phosphate-buffered saline solution containing the plaque samples of the patients was transferred evenly onto the sterile agar media. Equal segments of 100% neem oil coated (Group 1), 50% neem oil coated (Group 2), triclosan-coated (Group 3), and uncoated (Group 4) sutures were placed on the agar plate. These were then incubated at 37°C for 24 h. The inhibition zone was calculated in mm by measuring of the zone of inhibition (ZOI) in terms of length, breadth, and area. Results: The results were calculated following the incubation. The mean length for 100% neem oil-coated suture was 2.61 mm ± 0.2 and for 50% neem oil-coated suture was 2.49 mm ± 0.24. The mean breadth for 100% neem oil-coated suture was 1.5 mm ± 0.41 and for 50% neem oil-coated suture the mean was 0.95 mm ± 0.58. The mean area for 100% neem oil-coated suture was 77 mm ± 32.9 and for 50% neem oil-coated suture was 16.8 mm ± 11.14. Triclosan and uncoated sutures did not show any ZOI. Conclusion: The 100% neem oil-coated sutures had the largest length, breadth, and area of ZOI in the anaerobic culture media, followed by 50% neem oil-coated sutures. Triclosan-coated and uncoated sutures did not show any ZOI. Therefore, neem oil-coated suture can be used in the overall healing and prevention of postoperative discomfort after oral surgical procedures.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

A comparative assessment of antibacterial properties of neem oil coated sutures: An in vitro study

Kaur,

Sekhar,

Sharma

et al. 2023

Journal of Indian Society of Periodontology

View full text Add to dashboard Cite

show abstract

“…We have randomly taken the strains of MRSA, MRCONS, Staphylococcus hemolyticus, E. Coli, Klebsiella, & Acinetobacter species isolated from clinical samples of SSI & these strains were tested against triclosan coated & non coated sutures which are commercially available (Ethicon). Lawn culture of isolated organisms were made on Muller Hinton Agar (MHA) plates by using 0.5 McFarland standard (corresponds to 1.5 x 10 8 bacteria/ml) 7 of above strains by touching 4 to 5 colonies of each bacterium. 16 Similar length of (4cm) of triclosan coated & non coated sutures cut with aseptic precautions & placed on half of inoculated plates each.…”

Section: In -Vitro Testing Of Triclosan Coated and Uncoated Sutures Against The Bacteria Isolated From Ssimentioning

confidence: 99%

“…5,6 SSI increases morbidity & mortality in post surgical patients 3 , & also increases hospital stay, it affects quality of life and increases financial burden to healthcare system. [7][8][9][10] it may lead to major complications such as sepsis and death. 11 Patient related risk factors are smoking, obesity and diabetes.…”

Section: Introductionmentioning

confidence: 99%

“…SSI are classified into superficial incisional SSI, deep incisional SSI, & organ/space SSI. 16 Triclosan coated sutures reduce the colonization of bacteria 7 & biofilm formation on suture material. 17 Sutures in contaminated tissues may enhance penetration of micro organisms in deeper tissues & biofilm formation and this may protect organisms from host defence mechanism.…”

Section: Introductionmentioning

confidence: 99%

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In vitro comparison of efficacy of triclosan coated & uncoated sutures against the bacteria isolated from SSI at tertiary care hospital, Aurangabad

Mulay¹,

Pohekar²

2020

IJMR

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Most common Health Care Associated Infections (HAI) are Urinary tract infection (UTI) -33%, Pneumonia -15%, Surgical Site Infections (SSI) -15%, Blood stream infections -13%, & other miscellaneous infections -24%. SSI is defined as infection at the surgical site that occurs within 30 days of the surgical procedure or within one year -if there is an implant or foreign body such as prosthetic heart valve or joint prosthesis. Wound infections are always multifactorial. Risk factors for SSI include co-morbidity, malnutrition, nicotine, suture and implanted foreign material. SSI increases morbidity & mortality in post surgical patients, & also increases hospital stay, it affects quality of life and increases financial burden to healthcare system. It may lead to major complications such as sepsis and death. Patient related risk factors are smoking, obesity and diabetes. Skin preparation with antiseptic and preoperative antibiotic prophylaxis for clean-contaminated and contaminated surgery have proved efficient for decreasing SSI. Sutures in contaminated tissues may enhance penetration of micro organisms in deeper tissues & biofilm formation and this may protect organisms from host defence mechanism. One of the risk factors is the foreign material which includes suture. Commonly isolated pathogens from SSI are Staphylococcus aureus, CONS, Enterococcus species, E.coli & resistant pathogens like MRSA & candida (due to widespread use of broad spectrum anti-microbial agents.) In this study we have compared in vitro efficacy of triclosan coated polyglactin 910 suture with non -coated sutures against common bacteria isolated from SSI. Materials and Methods: We have randomly selected the strains of MRSA, MRCONS, Staphylococcus hemolyticus, E. Coli, Klebsiella, & Acinetobacter species isolated from clinical samples of SSI. These isolates were tested against triclosan coated & non coated sutures which are commercially available. Similar length of (4cm) of sutures cut & tested for zone of inhibition on lawn culture made on Muller Hinton Agar (MHA) by using 0.5 McFarland standard of above strains by touching 4 to 5 colonies of each bacterium. It is incubated overnight at 37 0 C & examined for zone of inhibition. Results: zone of inhibition of coated & uncoated sutures has been measured & compared for each strain. Conclusion: In vitro, triclosan coated sutures showed good antibacterial activity than non coated sutures & hence triclosan coated sutures may help in reducing bacterial SSI rate and thus reduce cost & duration of hospital stay for the patient.

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In-vitro Comparison of Antibacterial (Triclosan) Coated Suture Material with Non-coated Suture Material against common Bacterial pathogens Causing Surgical Site Infection

Cited by 2 publications

References 11 publications

A comparative assessment of antibacterial properties of neem oil coated sutures: An in vitro study

A comparative assessment of antibacterial properties of neem oil coated sutures: An in vitro study

In vitro comparison of efficacy of triclosan coated & uncoated sutures against the bacteria isolated from SSI at tertiary care hospital, Aurangabad

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