In Vitro Cytotoxicity of Maxillofacial Silicone Elastomers: Effect of Nano‐particles

Akay, Canan; Çevik, Pınar; Karakış, Duygu; Sevim, Handan

doi:10.1111/jopr.12533

Cited by 19 publications

(17 citation statements)

References 26 publications

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“…showed that nanoparticles such as nano-TiO 2 , fumed silica, and silaned silica added to a silicone-based elastomer used for fabrication of maxillofacial prostheses are nontoxic. [ 29 ] Other nanoparticles like ZnO, CeO 2 , BaSO 4 , Al 2 O 3 , SiO 2 , POSS which were used to improve the properties of silicone elastomer material requires evaluation of their biocompatibility in future research [ Table 5 ].…”

Section: Discussionmentioning

confidence: 99%

Effect of nanoparticles on color stability and mechanical and biological properties of maxillofacial silicone elastomer: A systematic review

Sonnahalli

Chowdhary

2020

J Indian Prosthodont Soc

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Aim: The aim of this systematic review was to evaluate the effect of addition of various nanoparticles into maxillofacial silicone elastomer on color stability and mechanical and biological properties of the silicone elastomer. Settings and Design: This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines(PRISMA). Materials and Methods: The electronic database search in MEDLINE/PubMed was based on population (silicone elastomer), intervention (nanoparticles), comparison (unreinforced silicone elastomer with nanoparticle-reinforced silicone elastomer), outcome (color stability and mechanical, physical, and biological properties), i.e., PICO framework. The key words used are (”maxillofacial silicone” OR “silicone elastomer” OR “facial silicone”) AND (”nanoparticles” OR “Nano-oxides”) AND (”colour stability” OR “Hardness,” “tensile strength” OR “tear strength” OR “antifungal activity”). Results: The database search resulted in 2099 studies, of which 2066 articles were excluded as they were irrelevant, duplicates, and data were not available. The remaining 33 full-text articles were assessed for eligibility, out of which 2 articles were in Chinese language, 3 articles were thesis documents, and 8 were review articles. A total of 12 articles were excluded and the remaining 20 articles were included. One article was yielded by hand search of references of included studies. A total of 21 studies were included in the present systematic review. Conclusion: With the available evidence in the literature, it can be concluded that addition of nanoparticles at various concentrations may improve the physical and mechanical properties and color stability of the prosthesis made from the silicone elastomers.

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Section: Discussionmentioning

confidence: 99%

Effect of nanoparticles on color stability and mechanical and biological properties of maxillofacial silicone elastomer: A systematic review

Sonnahalli

Chowdhary

2020

J Indian Prosthodont Soc

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“…Assessment of cell viability was performed based on a previous study [25]. Cytotoxicity was assessed with a tetrazolium salt 3-[4,5-dimethylthiazol-2-yl]-2,5-diphnyltetrazolium bromide (MTT) (M5655; Sigma-Aldrich, St. Louis, MO, USA) assay.…”

Section: Cell Viability Assessmentmentioning

confidence: 99%

Effect of Potassium Aluminum Sulfate Application on the Viability of Fibroblasts on a CAD-CAM Feldspathic Ceramic before and after Thermocycling

et al. 2022

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Potassium aluminum sulfate (alum) is a known adjuvant, which has been used as a mordant in textile industry for color fixation. This material has potential to be incorporated into dentistry for color stability, yet its toxicity first needs to be evaluated. The present study aimed to evaluate the cytotoxic potential of potassium aluminum sulfate (alum) on fibroblasts when applied onto feldspathic ceramic before and after thermocycling. Forty-eight feldspathic ceramic specimens were divided into four groups (FC: no alum application or thermocycling; FCT: thermocycling without alum application; FA: alum application without thermocycling; FAT: alum application and thermocycling) (n = 12). Cell viability was assessed by using a tetrazolium salt 3-[4,5-dimethylthiazol-2-yl]-2,5-diphnyltetrazolium bromide assay at 24 and 72 h, and cell cultures without any ceramic specimens served as control (C). One sample from each material group was further analyzed with energy dispersive X-ray spectroscopy (EDX). Cell viability at different time intervals within each group was analyzed with Friedman tests, while Kruskal–Wallis tests were used to compare the test groups within each time interval. Pairwise comparisons were further resolved by using Wilcoxon tests (a = 0.05). C had lower (p = 0.01) and FA had higher (p = 0.019) cell viability after 72 h. After 24 h, the highest cell viability was observed in C (p ≤ 0.036). After 72 h, the differences between C and FA, C and FAT, FC and FA, and FCT and FAT were nonsignificant (p > 0.05). Cell viability was not affected by alum application or thermocycling at any time interval (p ≥ 0.631). EDX analysis showed an increase in potassium concentration in FA and FAT when compared with FC and FCT. Regardless of the time interval, alum application onto feldspathic ceramic and thermocycling did not influence the cell viability.

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“…Nanoparticles of TiO 2 , smoldered silica, and silaned silica added to a silicone-based elastomer utilized for the manufacture of maxillofacial prostheses were found to be nontoxic. 47 Monodispersed polystyrene particles, with distances in the scope of many nanometers, were infused onto the stretched film. Furthermore, a close-pressed monolayer of particles was self-collected and connected on the best surface of the film because of its viscidity.…”

Section: Efficient Electrical Energy With Dielectric Elastomersmentioning

confidence: 99%

Smart materials for changing the electrical properties of nanostructures

Abbas

2021

Composites and Advanced Materials

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Smart materials have an important role in modern applications. They have contributed to improving various applications in several fields. One of the areas most affected by the improvement of smart materials is nanostructures. These materials are created by basic techniques, such as arrangement manipulation. Significant efforts have been made to enhance smart materials so that they resemble natural materials in terms of accuracy, design, and utility. Here, a review of the latest research on smart materials that can alter the electrical properties of nanostructures is presented. The main objective of this review is to introduce the role of smart materials in controlling the electrical performance of nanostructures. Furthermore, this review proposes an analysis of the integration and cooperation of previous research, such as the use of a piezoelectric motor in the design of structural magnetic nanodevices to control these devices. Piezoelectric actuators can also be used to develop a new method for controlling PV modulators for fabricating a single-wall nanotube. This new proposal could alter the properties of many nanoscale systems serving several medical and engineering fields. Moreover, this review proposes a novel methodology for nanocoating by introducing an antireflective coating with multiple layers. This method can effectively enhance the functions of the nanoscale coating.

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In Vitro Cytotoxicity of Maxillofacial Silicone Elastomers: Effect of Nano‐particles

Abstract: Nanoparticles of TiO , fumed silica, and silaned silica added to a commercial silicone-based elastomer used for fabrication of maxillofacial prostheses are nontoxic.

Cited by 19 publications

References 26 publications

Effect of nanoparticles on color stability and mechanical and biological properties of maxillofacial silicone elastomer: A systematic review

Effect of nanoparticles on color stability and mechanical and biological properties of maxillofacial silicone elastomer: A systematic review

Effect of Potassium Aluminum Sulfate Application on the Viability of Fibroblasts on a CAD-CAM Feldspathic Ceramic before and after Thermocycling

Smart materials for changing the electrical properties of nanostructures

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