2010
DOI: 10.1016/j.actbio.2009.12.043
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In vitro cytotoxicity of porous silicon microparticles: Effect of the particle concentration, surface chemistry and size

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Cited by 163 publications
(138 citation statements)
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“…Another group of Si materials is based on bigger particles (100 nm-1000 nm) which are porous (mostly the so called mesoporous silicon which contains pores with diameters between 2-50 nm) or crystalline -prepared by ball milling [4] (the particle size varies from 100 nm up to 50 µm and exhibit usually no photoluminescence). Main advantage over other materials is that particles of mesoporous silicon have a big surface in respect to a small volume, which predetermine them as good drug delivery system or for enhancing sensitivity of analytical methods, such as DNA sensing [5], because they increase the amount of material in the sample area.…”
mentioning
confidence: 99%
“…Another group of Si materials is based on bigger particles (100 nm-1000 nm) which are porous (mostly the so called mesoporous silicon which contains pores with diameters between 2-50 nm) or crystalline -prepared by ball milling [4] (the particle size varies from 100 nm up to 50 µm and exhibit usually no photoluminescence). Main advantage over other materials is that particles of mesoporous silicon have a big surface in respect to a small volume, which predetermine them as good drug delivery system or for enhancing sensitivity of analytical methods, such as DNA sensing [5], because they increase the amount of material in the sample area.…”
mentioning
confidence: 99%
“…The interaction of hydrophilic NPs with the cells' membranes is weak, mediated by water molecules, which make the particle−cell interactions less likely to occur, [ 20,21 ] thus increasing the cytocompatibility of the NPs.…”
Section: In Vitro Cytotoxicitymentioning
confidence: 99%
“…The detailed preparation of the particles used has been described elsewhere [25,30,36,41]. Briefly, silicon wafers Sih10 0i of p + -type, with resistivity values of 0.008-0.020 X cm, were used in the preparation of the thermally carbonized-PSi (TCPSi) microparticles.…”
Section: Production Of the Tcpsi Microparticlesmentioning
confidence: 99%
“…Cell viability was expressed as the percentage of luminescence measured for the negative control (only buffer). Triton X-100 (Sigma-Aldrich, USA) was used as a positive control for cytotoxic activity [36].…”
Section: Viability Tests Cell Lines and Culturesmentioning
confidence: 99%
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