In Vitro Evaluation of Adhesion of <i>Candida albicans</i> on CAD/CAM PMMA‐Based Polymers

Murat, Sema; Alp, Gülce; Alatalı, Canan; Uzun, Meltem

doi:10.1111/jopr.12942

Cited by 88 publications

(106 citation statements)

References 44 publications

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“…Likewise, enhanced surface characteristics of CAD/CAM PMMA might be attributed to the unique manufacturing process of these materials; reduced levels of residual monomers as well as the polymerization method involved in PMMA manufacturing were previously reported to contribute to surface roughness alteration . The results of this study support Murat et al's results of lower R a values for the CAD/CAM PMMA group using a contact type profilometer and the results of Steinmassl et al, who tested different complete dentures of variable CAD/CAM PMMA brands and compared them to conventional dentures and reported significant lower roughness values for the CAD/CAM groups.…”

Section: Discussionsupporting

confidence: 85%

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A Comparison of the Surface Properties of CAD/CAM and Conventional Polymethylmethacrylate (PMMA)

Al-Dwairi

Tahboub

Baba

et al. 2019

Journal of Prosthodontics

135

127

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Purpose To compare surface properties of 2 brands of pre‐polymerized resin blocks for complete dentures (CAD/CAM PMMA) to conventional heat‐polymerized PMMA. Materials and Methods A total of 45 rectangular specimens (25 × 25 × 3 mm) were fabricated from 3 brands of PMMA (n = 15/group): AvaDent CAD/CAM PMMA, Tizian‐Schütz CAD/CAM PMMA, Meliodent conventional PMMA. Specimens were examined for wettability using the sessile drop method, surface roughness using a digital contact profilometer, and microhardness using Vickers hardness number. Statistical analysis was performed using one‐way ANOVA and Tukey pairwise multiple comparisons. p‐Values of ≤0.05 were considered significant. Results AvaDent specimens demonstrated the highest mean contact angle (72.87 ± 48°) and the highest mean Vickers hardness number (20.62 ± 0.33). The conventional heat‐polymerized specimens showed the highest mean surface roughness (0.22 ± 0.071 μm). Tizian‐Schütz specimens showed the lowest mean surface roughness (0.12 ± 0.02 μm). Conclusions As CAD/CAM PMMA groups exhibited significantly more favorable surface properties in comparison to the conventional heat‐polymerized groups, CAD/CAM dentures are expected to be more durable. Different brands of CAD/CAM PMMA may have inherent variations in surface properties.

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Section: Discussionsupporting

confidence: 85%

“…All contact angles obtained in this study were in line with the results of the aforementioned study. Murat et al reported a higher contact angle, and consequently, higher hydrophobicity of conventional heat‐cured PMMA when compared to CAD/CAM PMMA. The results they obtained were attributed to the effect of thermal cycling.…”

Section: Discussionmentioning

confidence: 99%

A Comparison of the Surface Properties of CAD/CAM and Conventional Polymethylmethacrylate (PMMA)

Al-Dwairi

Tahboub

Baba

et al. 2019

Journal of Prosthodontics

135

127

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“…The CAD/CAM technologies are used for the fabrication of various ceramic restorations, including inlays, onlays, crowns, and fixed partial dentures [ 202 ]. More recently, several researchers [ 203 , 204 , 205 , 206 , 207 , 208 , 209 , 210 , 211 ] investigated the use of CAD/CAM technologies for the fabrication of PMMA dental prostheses and compared the materials’ properties and various aspects of the conventional and CAD/CAM PMMA materials. In contrast to the conventional “flask–pack–press” technique, CAD/CAM techniques commonly use rapid prototyping and milling techniques [ 208 , 210 ].…”

Section: Applications Of Pmmamentioning

confidence: 99%

“…Interestingly, the adherence of fungal Candida albicans was remarkably reduced in CAD/CAM dentures [ 207 ], resulting in enhanced hydrophobicity and surface properties [ 205 , 206 , 207 ]. The increased hydrophobicity inhibits plaque accumulation on the polymer surface [ 213 , 214 ].…”

Section: Applications Of Pmmamentioning

confidence: 99%

Prosthodontic Applications of Polymethyl Methacrylate (PMMA): An Update

2020

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A wide range of polymers are commonly used for various applications in prosthodontics. Polymethyl methacrylate (PMMA) is commonly used for prosthetic dental applications, including the fabrication of artificial teeth, denture bases, dentures, obturators, orthodontic retainers, temporary or provisional crowns, and for the repair of dental prostheses. Additional dental applications of PMMA include occlusal splints, printed or milled casts, dies for treatment planning, and the embedding of tooth specimens for research purposes. The unique properties of PMMA, such as its low density, aesthetics, cost-effectiveness, ease of manipulation, and tailorable physical and mechanical properties, make it a suitable and popular biomaterial for these dental applications. To further improve the properties (thermal properties, water sorption, solubility, impact strength, flexural strength) of PMMA, several chemical modifications and mechanical reinforcement techniques using various types of fibers, nanoparticles, and nanotubes have been reported recently. The present article comprehensively reviews various aspects and properties of PMMA biomaterials, mainly for prosthodontic applications. In addition, recent updates and modifications to enhance the physical and mechanical properties of PMMA are also discussed.

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“…Additional information about the position of the regions of interest can PMMA has a permeability to gas neglectable compared to other polymers usually used in microfluidic forms, i.e., PDMS [55]. The mean contact angle of conventional PMMA is almost 75 • , this means that it is weakly hydrophilic [56]. As explained in Section 2.7, a priming of the waste reservoir with 200 µL of culture medium is preferred to overcome hydrophobic forces.…”

Section: Device Experimental Characterization and Validationmentioning

confidence: 99%

A Disposable Passive Microfluidic Device for Cell Culturing

et al. 2020

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In this work, a disposable passive microfluidic device for cell culturing that does not require any additional/external pressure sources is introduced. By regulating the height of fluidic columns and the aperture and closure of the source wells, the device can provide different media and/or drug flows, thereby allowing different flow patterns with respect to time. The device is made of two Polymethylmethacrylate (PMMA) layers fabricated by micro-milling and solvent assisted bonding and allows us to ensure a flow rate of 18.6 μL/h - 7%/day, due to a decrease of the fluid height while the liquid is driven from the reservoirs into the channels. Simulations and experiments were conducted to characterize flows and diffusion in the culture chamber. Melanoma tumor cells were used to test the device and carry out cell culturing experiments for 48 h. Moreover, HeLa, Jurkat, A549 and HEK293T cell lines were cultivated successfully inside the microfluidic device for 72 h.

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In Vitro Evaluation of Adhesion of Candida albicans on CAD/CAM PMMA‐Based Polymers

Abstract: CAD/CAM PMMA-based polymers may be preferable to reduce Candida-associated denture stomatitis in long-term use.

Cited by 88 publications

References 44 publications

A Comparison of the Surface Properties of CAD/CAM and Conventional Polymethylmethacrylate (PMMA)

A Comparison of the Surface Properties of CAD/CAM and Conventional Polymethylmethacrylate (PMMA)

Prosthodontic Applications of Polymethyl Methacrylate (PMMA): An Update

A Disposable Passive Microfluidic Device for Cell Culturing

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