In vitro evaluation of antibacterial activity of Asparagopsis taxiformis from the Straits of Messina against pathogens relevant in aquaculture

Genovese, Giuseppa; Faggio, Caterina; Gugliandolo, Concetta; Torre, Agata; Spanò, Antonio; Morabito, Marina; Maugeri, Teresa L.

doi:10.1016/j.marenvres.2011.10.002

Cited by 84 publications

(47 citation statements)

References 38 publications

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“…Different strains of V. harveyi and V. vulnificus were weakly inhibited by the ethanol extract of Asparagopsis taxiformis from the Sicily Channel [45]. Ethanol was also used for thalli of Gracilaria fisheri from India, the extract of which showed a high inhibition against V. harveyi [39].…”

Section: Discussionmentioning

confidence: 99%

Antibacterial activity of marine macroalgae against fish pathogenic Vibrio species

et al. 2013

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In mariculture, diseases of microbial origin can cause significant economic losses worldwide; the evolution of microorganism resistance to antibiotics has resulted in a growing need for new antibacterial compounds that are effective in veterinary medicine and characterized by limited undesirable side effects. Increased attention has recently been turned to seaweeds as a promising source for metabolites with antimicrobial activity. Vibriosis is a common disease, caused by bacteria of the genus Vibrio, that can result in high mortality in aquaculture. The aim of this study was to identify seaweeds with antibacterial activity against some pathogenic Vibrio species, in order to identify a possible alternative to the commonly used antibiotics in aquaculture. Chloroform/methanol lipidic extracts of six seaweed species (Chaetomorpha linum, Cladophora rupestris, Gracilaria dura, Gracilaria gracilis, Gracilariopsis longissima, Ulva prolifera) were tested for their antibacterial activities against six fish pathogenic Vibrio species using the disc diffusion method. Different susceptibilities to lipidic algal extracts were observed. All six of the seaweed extracts tested demonstrated inhibition of Vibrio ordalii. The best was that from Gracilariopsis longissima, showing activity against Vibrio ordalii, Vibrio salmonicida, Vibrio alginolyticus and Vibrio vulnificus. The results confirmed the potential use of seaweed extracts as a source of antibacterial compounds or as a health-promoting feed for aquaculture.

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Section: Discussionmentioning

confidence: 99%

Antibacterial activity of marine macroalgae against fish pathogenic Vibrio species

et al. 2013

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“…antiprotozoal properties [23][24][25][26][27][28][29] Thalli were manually cleaned and stored at -20°C. Crude extracts were obtained with ethanol at room temperature and dried by Rotavapor® at low temperature (35°C) to prevent volatile compounds from evaporation.…”

Section: Cell Sensitivity Assays: the Mtt Assaymentioning

confidence: 99%

Effectiveness of red alga Asparagopsis taxiformis extracts against Leishmania infantum

et al. 2015

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“…The genus Asparagopsis is known to biosynthesize about one hundred of halogenated volatile hydrocarbons containing one to four carbons with antimicrobial, antifeedant and cytotoxic properties (Genovese et al 2012;Kladi et al 2004;Paul et al 2006b). Assessment of resources allocated to defense traits can be obtained through analysis of the specialized metabolism using metabolomics.…”

Section: Introductionmentioning

confidence: 99%

Chemogeography of the red macroalgae Asparagopsis: metabolomics, bioactivity, and relation to invasiveness

et al. 2017

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Results Metabotypes showed a low divergence between tropical and temperate populations, while bioactivities were higher in temperate populations. However, these phenotypes varied significantly in time, with a higher variability in tropical regions. Bioactivities were high and stable in temperate regions, whereas they were low and much variable in tropical regions. Although the introduced lineage two exhibited the highest bioactivities, this lineage could also present variable proliferation fates. Conclusion The metabolomic approach partly discriminates macroalgal populations from various geographic origins. The production of chemical defenses assessed by the bioactivity assay does not match the macroalgal genetic lineage and seems more driven by the environment. The higher content of chemical defenses in temperate versus tropical populations is not in accordance with the LGH and cannot be related to the invasiveness of the macroalgae. AbstractIntroduction The Latitudinal Gradient Hypothesis (LGH) foresees that specialized metabolites are overexpressed under low latitudes, where organisms are subjected to higher herbivory pressure. The widespread macroalga Asparagopsis taxiformis is composed of six distinct genetic lineages, some of them being introduced in many regions. Objectives To study (i) metabolic fingerprints of the macroalga and (ii) its bioactivity in space and time, both as proxies of its investment in defensive traits, in order to assess links between bioactivities and metabotypes with macroalgal invasiveness. Methods 289 macroalgal individuals, from four tropical and three temperate regions, were analyzed using untargeted metabolomics and the standardized Microtox® assay.

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In vitro evaluation of antibacterial activity of Asparagopsis taxiformis from the Straits of Messina against pathogens relevant in aquaculture

Cited by 84 publications

References 38 publications

Antibacterial activity of marine macroalgae against fish pathogenic Vibrio species

Antibacterial activity of marine macroalgae against fish pathogenic Vibrio species

Effectiveness of red alga Asparagopsis taxiformis extracts against Leishmania infantum

Chemogeography of the red macroalgae Asparagopsis: metabolomics, bioactivity, and relation to invasiveness

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