In vitro evaluation of the vasodilatory activity of ethanol extracts of Eleutherine bulbosa bulbs and leaves

Fikriah, Ika; Ismail, Sjarif; Kosala, Khemasili

doi:10.7324/japs.2021.110518

Cited by 4 publications

(3 citation statements)

References 17 publications

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“…Several studies have shown that quercetin has positive effects on cardiovascular diseases. Suri et al evaluated the impact on vasoconstrictor and vasodilator reactions in the porcine heart, reporting that quercetin increased both cyclic guanosine mono-phosphate (cGMP) content and cGMP-dependent relaxations to glyceryl trinitrate (GTN) and sodium nitroprusside (SNP), as well as porcine receptor-mediated restrained contractions [ 45 ]. Also, a study with rats showed that quercetin (0.1–100 μM) relaxed the contraction induced by pretreatment with five mM norepinephrine in a concentration-dependent manner.…”

Section: Quercetin Particularitiesmentioning

confidence: 99%

Quercetin, a Flavonoid with Great Pharmacological Capacity

Carrillo-Martinez,

Flores-Hernández,

Salazar-Montes

et al. 2024

Molecules

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Quercetin is a flavonoid with a low molecular weight that belongs to the human diet’s phenolic phytochemicals and nonenergy constituents. Quercetin has a potent antioxidant capacity, being able to capture reactive oxygen species (ROS), reactive nitrogen species (RNS), and reactive chlorine species (ROC), which act as reducing agents by chelating transition-metal ions. Its structure has five functional hydroxyl groups, which work as electron donors and are responsible for capturing free radicals. In addition to its antioxidant capacity, different pharmacological properties of quercetin have been described, such as carcinostatic properties; antiviral, antihypertensive, and anti-inflammatory properties; the ability to protect low-density lipoprotein (LDL) oxidation, and the ability to inhibit angiogenesis; these are developed in this review.

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Section: Quercetin Particularitiesmentioning

confidence: 99%

Quercetin, a Flavonoid with Great Pharmacological Capacity

Carrillo-Martinez,

Flores-Hernández,

Salazar-Montes

et al. 2024

Molecules

View full text Add to dashboard Cite

show abstract

“…Several studies have shown that quercetin has positive effects on cardiovascular diseases. Suri et al evaluated the impact on vasoconstrictor and vasodilator reactions in the porcine heart, reporting that quercetin increased both cyclic guanosine mono-phosphate (cGMP) content and cGMP-dependent relaxations to glyceryl trinitrate (GTN) and sodium nitroprusside (SNP), as well as porcine receptor-mediated restrained contractions [45]. Also, a study with rats showed that quercetin (0.1-100 µM) relaxed the contraction induced by pretreatment with five mM norepinephrine in a concentration-dependent manner.…”

Section: Cardiovascular Protectionmentioning

confidence: 99%

Quercetin, A Flavonoid With Great Pharmacological Capacity

Carrillo-Martinez,

Flores-Hernández,

Salazar-Montes

et al. 2024

Preprint

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Quercetin is a flavonoid with a low molecular weight that belongs to the human diet's phenolic phytochemicals and non-energy constituents. Quercetin has a potent antioxidant capacity, being able to capture Reactive Oxygen Species (ROS), reactive nitro-gen species (RNS), and Reactive Chlorine Species (ROC), which act as reducing agents by chelating transition metal ions. Its structure has five functional hydroxyl groups, which work as electron donors and are responsible for capturing free radicals. In addition to its antioxidant capacity, it was described different pharmacological properties of Quercetin, such as carcinostatic properties, antiviral, antihypertensive, anti-inflammatory, protection of Low-Density Lipoprotein (LDL) oxidation, and inhibi-tion of angiogenesis are developed in this review.

show abstract

“…Several studies have shown that Quercetin has positive effects on cardiovascular diseases. Suri et al evaluated the impact on vasoconstrictor and vasodilator reactions in the porcine heart, reporting that Quercetin increases both Cyclic Guanosine Mono-phosphate (cGMP) content and cGMPdependent relaxations to Glyceryl Trinitrate (GTN) and Sodium Nitroprusside (SNP), as well as porcine receptor-mediated restrained contractions [45]. Also, a study with rats showed that Quercetin (0.1-100 μM) relaxed the contraction induced by pretreatment with five mM norepinephrine in a concentration-dependent manner.…”

Section: Cardiovascularmentioning

confidence: 99%

Design and Parameterization of a Computational Model Based on Convolutional Neural Networks for Mango Selection

Salazar-Campos,

Ruiz

et al. 2024

Preprint

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In recent times, using image-based deep learning techniques has been very useful for classifying fruits. However, mango is a particular challenge because its shelf life is directly related to the degree of maturity at the time of harvest, which is determined mainly through the visual assessment of the operators when sorting them, doing it incorrectly, coupled with the blows and compressions exposed during storage and transport, trigger the deterioration in their quality, hence the importance of this operation. In this sense, the purpose of this study focuses on designing a computational model based on Deep Learning that uses a convolutional neural network (CNN) parameterized to select mangoes according to their color tone based on their maturity stage. A dataset was established from 201 labeled images, then a CNN architecture was built, obtaining a model on which 3 criteria were evaluated: the number of convolution and grouping layers, the resolution of the input images and the number of training epochs required. As a result, an input image resolution of 32 x 32 pixels was achieved, the process included a convolution layer followed by pooling that fed another layer that processed the results and ended in an output layer with 2 neurons under the One Hot Encoding representation. The model required 20 epochs to perfect its training, achieving 96.04 % accuracy in mango image selection. This study supports the potential of CNNs in quality analysis through mango color selection, even in uncertainty scenarios.

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In vitro evaluation of the vasodilatory activity of ethanol extracts of Eleutherine bulbosa bulbs and leaves

Cited by 4 publications

References 17 publications

Quercetin, a Flavonoid with Great Pharmacological Capacity

Quercetin, a Flavonoid with Great Pharmacological Capacity

Quercetin, A Flavonoid With Great Pharmacological Capacity

Design and Parameterization of a Computational Model Based on Convolutional Neural Networks for Mango Selection

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