In vitro evidence of involvement of the epithelial y+ transporter in β-defensin production on the ocular surface

Jäger, Kristin; Nielitz, Andrea; Garreis, Fabian; Sel, Saadettin; Nave, Heike; Paulsen, Friedrich

doi:10.1016/j.aanat.2011.10.001

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“…The authors observed that HBD-1 and HBD-2 are produced by the ocular surface, whilst ␣-defensins 1, 2 and 3 are present in the conjunctival lamina propria and epithelium and are then released into the ocular surface fluids by neutrophils and possibly by secretions from lachrymal ductular epithelia [35]. HBD-3 is a recently discovered member of the host defence peptide group and its expression by corneal and conjunctival epithelial cells has been confirmed [47,52]. HBD-4 and HBD-9 have also been detected on the ocular surface [53][54][55].…”

Section: Defensinsmentioning

confidence: 91%