In vitro fermentation of sulfated polysaccharides from E. prolifera and L. japonica by human fecal microbiota

Kong, Qing; Dong, Shiyuan; Gao, Jian; Jiang, Chaoyu

doi:10.1016/j.ijbiomac.2016.06.036

Cited by 106 publications

(59 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Prebiotic formulations can be selectively utilized (as a carbon sources) by beneficial microbes as a result of differences in their microbial machinery (Barrangou, Altermann, Hutkins, Cano, & Klaenhammer, ). Recent studies on interaction between prebiotics and gut microbes have shown that they stimulate the growth and activities of intestinal bacteria especially beneficial bacterial strains, Bifidobacteria and Lactobacilli, which are known to modulate immune response (Charoensiddhi et al, ; Delgado, Tamashiro, & Pastore, ; Kong et al, ; Lynch et al, ). In addition, metabolic products from prebiotics have suppressed the growth of certain bacteria as well (Shibata et al, ).…”

Section: Prebiotics Bsp and Immunomodulation: Evidence And Mechanismmentioning

confidence: 99%

“…Additionally, it is time consuming, requires a lot of work to accomplish, and is associated with errors especially in bacteria counting (Gong & Yang, 2012). This method has been widely used for studying the prebiotic activity of BSP since beneficial bacteria population, Bifidobacteria and Lactobacilli, are culturable (Kong et al, 2016;Lynch et al, 2010;Wang et al, 2006;Zhao & Cheung 2011).…”

Section: Stimulation Of Activity/growth Of Intestinal Bacteriamentioning

confidence: 99%

See 1 more Smart Citation

Prospects of brown seaweed polysaccharides (BSP) as prebiotics and potential immunomodulators

et al. 2017

View full text Add to dashboard Cite

Prebiotics enhance immune response through the modulation of intestinal microbial activities, production of short chain fatty acids (SCFA), direct interaction with toll‐like receptors and mucin production. These non‐digestible food components are known to be resistant to enzymatic hydrolysis by digestive enzymes and are utilized as carbon source for the growth of beneficial bacteria population through the process of fermentation. Brown seaweed polysaccharides (BSP) have been described as emerging prebiotics due to their potential to stimulate gut microbiota activities at in vitro and in vivo stages. This review therefore examines evidence of the relationship between the prebiotic capacity of BSP, their structure, extraction, and possible mechanisms of immunomodulation. Practical applications Bio‐functional ingredients have been widely explored for numerous health benefits. Of interest to this review are polysaccharides of brown seaweed which have great prebiotic prospects. Prebiotics are important bio‐functional ingredients having the potential to improve immune health. An understanding of the prebiotic and immunomodulatory potential of BSP provides the food industry a novel alternative source of prebiotics. Excerpts from this review will provide background knowledge and advance scientific research into prospects of BSP as prebiotics and a possible commercialization of BSP products.

show abstract

Section: Prebiotics Bsp and Immunomodulation: Evidence And Mechanismmentioning

confidence: 99%

Section: Stimulation Of Activity/growth Of Intestinal Bacteriamentioning

confidence: 99%

Prospects of brown seaweed polysaccharides (BSP) as prebiotics and potential immunomodulators

et al. 2017

View full text Add to dashboard Cite

show abstract

“…In this sense, the ability of the GM to extract energy from specific components of the diet offers a direct competitive advantage to specific members of the GM, allowing them to proliferate at the expense of other members [81]. Thus, diet affects not only the composition and absolute abundance of intestinal bacteria but also their growth kinetics [82]. In this context, the most influential nutrients are indigestible carbohydrates, which can be of both terrestrial and marine algae origin [81].…”

Section: Effects Of Seaweed Polysaccharides On Human Healthmentioning

confidence: 99%

“…In this table it were included results about the prebiotic effect of brown seaweed species from genus Ecklonia [7,85], Sargassum [86][87][88], Laminaria [82,[89][90][91][92], Ascophyllum [93][94][95], Fucus [23,63], Undaria [90], Saccorhiza [96] or Porphyra [97]. As can be seem in Table 1, in most cases, the administration of whole brown seaweed or brown seaweed-extracted polysaccharides resulted in an increase of SCFA production, stimulating of beneficial bacteria grown such as Lactobacillus [7,82,85,86,95], Bifidobacterium [7,82,85,87,92] or Faecalibacterium [7,58,87]. In some cases, the brown seaweed or brown seaweed-extracted polysaccharides also inhibited the growth of potentially pathogen bacteria [73,86].…”

Section: Polysaccharides From Brown Seaweedsmentioning

confidence: 99%

Potential Use of Marine Seaweeds as Prebiotics: A Review

et al. 2020

View full text Add to dashboard Cite

Human gut microbiota plays an important role in several metabolic processes and human diseases. Various dietary factors, including complex carbohydrates, such as polysaccharides, provide abundant nutrients and substrates for microbial metabolism in the gut, affecting the members and their functionality. Nowadays, the main sources of complex carbohydrates destined for human consumption are terrestrial plants. However, fresh water is an increasingly scarce commodity and world agricultural productivity is in a persistent decline, thus demanding the exploration of other sources of complex carbohydrates. As an interesting option, marine seaweeds show rapid growth and do not require arable land, fresh water or fertilizers. The present review offers an objective perspective of the current knowledge surrounding the impacts of seaweeds and their derived polysaccharides on the human microbiome and the profound need for more in-depth investigations into this topic. Animal experiments and in vitro colonic-simulating trials investigating the effects of seaweed ingestion on human gut microbiota are discussed.

show abstract

“…In addition, the pH and the contents of SCFAs were found to have some significant changes in the fermentation of human faecal samples. (Kong et al , ; Chen et al , ). There are similar results in the simulated digestion of other polysaccharides in vitro (Gao et al , ; Hu et al , ; Xu et al , ).…”

Section: The Digestive Behaviour Of Bspmentioning

confidence: 99%

Beneficial effects of three brown seaweed polysaccharides on gut microbiota and their structural characteristics: An overview

You

Gong

et al. 2019

Int J of Food Sci Tech

View full text Add to dashboard Cite

Summary The gut microbiota appears critical in the metabolic health and anti‐disease activity. In this review, we discuss three brown seaweed polysaccharides (alginate, laminarin, fucoidan) for their structural information, the digestive behaviour and the effects on gut microbiota. Bioactivities are associated with various physicochemical properties, like solubility, viscosity, hydration properties, molecular weight, monosaccharide composition, and so on. Brown seaweed polysaccharides can be completely utilised by microbes in the large bowel, and they can regulate the gut microbiota. The ultimate metabolite of these polysaccharides is mainly short‐chain fatty acids, which are able to regulate the ecology of the gut microbiota by increasing the growth of beneficial bacteria and inhibiting the growth of some harmful bacteria. In addition, this article also discusses the relationship between the structure and activity of modulating the gut microbiota. Results show that polysaccharides with low molecular weight are more conductive to modulate gut microbiota.

show abstract

In vitro fermentation of sulfated polysaccharides from E. prolifera and L. japonica by human fecal microbiota

Cited by 106 publications

References 28 publications

Prospects of brown seaweed polysaccharides (BSP) as prebiotics and potential immunomodulators

Prospects of brown seaweed polysaccharides (BSP) as prebiotics and potential immunomodulators

Potential Use of Marine Seaweeds as Prebiotics: A Review

Beneficial effects of three brown seaweed polysaccharides on gut microbiota and their structural characteristics: An overview

Contact Info

Product

Resources

About