In vitro interleukin-1 and tumor necrosis factor-alpha production by macrophages from chickens infected with either Eimeria maxima or Eimeria tenella

Byrnes, Sheri; Eaton, Rayetta; Kogut, Michael H.

doi:10.1016/0020-7519(93)90170-4

Cited by 56 publications

(31 citation statements)

References 31 publications

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“…Rautenschlein et al (1999) demonstrated for the first time that chicken TNF has several functions homologous to mammalian TNF-α and the authors concluded that chicken macrophages indeed secrete a TNF-like factor, comparable in its activities with mammalian TNF-α. Other studies have indicated that chicken cells produce TNF following LPS or Eimeria stimulation (Byrnes et al 1993, Zhang et al 1995a1995b). Gehad et al (2002) observed an increase in TNF-α release following the injection of LPS in chickens and conclude that TNF-α is an equally important mediator of sepsis in chickens as well as mammals.…”

Section: Discussionmentioning

confidence: 92%

The role of chicken IL-1β, IL-6 and TNF-α in the occurrence of amyloid arthropathy

et al. 2008

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In this study, the roles of IL-1beta, IL-6 and TNF-alpha in amyloid arthropathic chickens with variable amounts (severe, moderate and mild) of amyloid accumulation were investigated. The presence and the levels of cytokines were evaluated in serum and in joint tissues by using ELISA and immunohistochemistry, respectively. One hundred brown layer chicks were allocated into four groups and intra-articular injections of Freund's adjuvant were used to induce amyloid arthropathy in Groups II, III and IV. Vitamin A in group II, and methylprednisolone in Group IV were added to enhance and to reduce the severity of amyloidosis, respectively. At the end of the study, a positive correlation was observed among the incidence and severity of amyloidosis, the serum amyloid A levels and the IL-1beta values both in the serum and tissues. Elevation in the tissue TNF-alpha levels in parallel with the severity of amyloidosis has also been noted. As a conclusion, IL-1beta appears to play an important role in avian AA amyloidosis either alone or in combination with TNF-alpha. Further investigation is needed for understanding the role of the pro-inflammatory cytokines in avian AA amyloidosis.

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Section: Discussionmentioning

confidence: 92%

The role of chicken IL-1β, IL-6 and TNF-α in the occurrence of amyloid arthropathy

et al. 2008

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“…Byrnes et al (1993) reported that the levels of IL-1 produced in chickens infected with E. tenella or E. maxima were nearly identical regardless of the oocyst dose and species of Eimeria , and TNFa production followed a biphasic pattern whereby the first and the second peak was associated with disease pathogenesis and the development of protective immunity. In our study, dietary fish oil or corn oil supplementation did not ameliorate the lesion score caused by E. tenella.…”

Section: Discussionmentioning

confidence: 99%

Fatty acids and coccidiosis: effects of dietary supplementation with different oils on coccidiosis in chickens

et al. 2006

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“…Tumor necrosis factor (TNF), an inflammatory cytokine, is secreted by activated macrophages. TNF-␣-like activity can be detected in stimulated macrophages from infected chickens (22,114) and in sera from infected chickens (113). Treatment of infected chickens with TNF-␣ exacerbated the suppression of weight gain due to infection, whereas treatment with polyclonal antibodies to TNF-␣ partially reversed the weight gain depression (114).…”

Section: Immunobiologymentioning

confidence: 99%

Recent Advances in Biology and Immunobiology ofEimeriaSpecies and in Diagnosis and Control of Infection with These Coccidian Parasites of Poultry

2002

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SUMMARY Avian coccidiosis, an intestinal disease caused by protozoan parasites of the genus Eimeria, occurs worldwide. It is considered to be one of the most economically important diseases of domestic poultry. For many years, prophylactic use of anticoccidial feed additives has been the primary means of controlling coccidiosis in the broiler industry and has played a major role in the growth of this industry, which now can produce about 7.6 billion chickens annually. However, development of anticoccidial resistance has threatened the economic stability of the broiler industry. Although there has been little effort by the pharmaceutical industry to develop new anticoccidials, the mounting problem of drug resistance of Eimeria species has prompted major research efforts to seek alternative means of control through increased knowledge of parasite biology, host response, and nutritional modulation. As a consequence, important advancements have been made, particularly in defining parasite antigens that have potential use in vaccines, defining the Eimeria genome, understanding the immunology of coccidial infections, and the practical applications of live vaccines. This review describes the progress in these areas, most of which has occurred within the past 10 to 15 years.

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In vitro interleukin-1 and tumor necrosis factor-alpha production by macrophages from chickens infected with either Eimeria maxima or Eimeria tenella

Cited by 56 publications

References 31 publications

The role of chicken IL-1β, IL-6 and TNF-α in the occurrence of amyloid arthropathy

The role of chicken IL-1β, IL-6 and TNF-α in the occurrence of amyloid arthropathy

Fatty acids and coccidiosis: effects of dietary supplementation with different oils on coccidiosis in chickens

Recent Advances in Biology and Immunobiology ofEimeriaSpecies and in Diagnosis and Control of Infection with These Coccidian Parasites of Poultry

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