In Vitro Phytotoxicity and Antioxidant Activity of Selected Flavonoids

Abstract

The knowledge of flavonoids involved in plant-plant interactions and their mechanisms of action are poor and, moreover, the structural characteristics required for these biological activities are scarcely known. The objective of this work was to study the possible in vitro phytotoxic effects of 27 flavonoids on the germination and early radical growth of Raphanus sativus L. and Lepidium sativum L., with the aim to evaluate the possible structure/activity relationship. Moreover, the antioxidant activity of the same compounds was also evaluated. Generally, in response to various tested flavonoids, germination was only slightly affected, whereas significant differences were observed in the activity of the various tested flavonoids against radical elongation. DPPH test confirms the antioxidant activity of luteolin, quercetin, catechol, morin, and catechin. The biological activity recorded is discussed in relation to the structure of compounds and their capability to interact with cell structures and physiology. No correlation was found between phytotoxic and antioxidant activities.

Dietary Flavonoid Aglycones and Their Glycosides: Which Show Better Biological Significance?

“…Cai and others (2006) evaluated the structure-radical scavenging activity relationships of flavonols, flavones, flavanones, and isoflavones from the traditional Chinese medicines by ABTS assay and DPPH assay and the results were expressed in terms of TEAC (mM). Quercetin and kaempferol appears higher and OH groups reduced the DPPH free radical scavenging potential (De Martino et al, 2012;Wang et al, 2012b;Sarkar et al, 2012;Om et al, 2008;Rice-Evans et al, 1996;Cai et al, 2006). …”

Seasonal variation in allelopathic potential of the leaves of Copaifera langsdorffii Desf.

“…e mixtures of chemical substances present in the C. langsdor i leaf extracts (composed mostly of avonoids) could alter membrane integrity and polarity as well as the function of transport proteins (Hedrich, 2012;Martino et al 2012). is could explain the phenotypic characteristics found in seedlings treated with WSE, where the roots were extremely short and deformed.…”

“…Martino et al (2012) showed that the e ect of various avonoids on initial root growth was substantially inhibited, while germination was only slightly a ected.…”

Assessment of In vivo antioxidant properties of Dacryodes edulis and Ficus exasperata as anti-malaria plants

“…The inclusion of these plants amongst others used for malaria treatment is not unconnected with the antioxidative stress exhibited by the plants, which is directly linked with antioxidant potential of several phytochemicals of the plants species [4,7,12,[25][26][27][28] . Previous studies have shown that the plants was multipurpose species in African folk medicine in the treatment of several diseases conditions.…”