2009
DOI: 10.1016/j.tiv.2009.01.008
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In vitro selection and efficacy of topical skin protectants against the nerve agent VX

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Cited by 16 publications
(9 citation statements)
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References 28 publications
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“…41 Polymers have excellent wetting and film-forming properties and have shown to significantly affect the skin protective efficacy of barrier formulations. 42 The newest polymers are also water repellent. 41 Numerous other substances are commonly found in BCs with the aim to enhance protection against irritants and skin health.…”
Section: Hydrating Agentsmentioning
confidence: 99%
“…41 Polymers have excellent wetting and film-forming properties and have shown to significantly affect the skin protective efficacy of barrier formulations. 42 The newest polymers are also water repellent. 41 Numerous other substances are commonly found in BCs with the aim to enhance protection against irritants and skin health.…”
Section: Hydrating Agentsmentioning
confidence: 99%
“…omogućiti brzu neutralizaciju svih kemijskih i bioloških agensa, stabilnost i jednostavnost primjene te uporabljivost za različite vrste dekontaminacije, biti inertni prema različitim konstrukcijskim materijalima, netoksični, postojani, dostupni s relativno niskom cijenom, primjenjivi u različitim klimatskim uvjetima te ekološki prihvatljivi. [2][3][4][5][6][7][8][9] Većina javnosti ne zna kako se uništavalo kemijsko oružje i streljivo u prošlosti (zakopavanje ili bacanje u rijeke, jezera i mora) te kakve su posljedice i potencijalne opasnosti takvih postupaka. Prevladava stručno mišljenje da je pouzdanost kemijskog streljiva do pedesetak godina a da nakon tog razdoblja započinje proces kada je moguće istjecanje kemijskih agenasa.…”
Section: Uvodunclassified
“…A number of such skin protectants have been tested in vitro and some have begun safety testing in humans. 283 Experiments with bioscavengers as alternatives to traditional nerve agent treatment are also being reported. A human serum butyrylcholinesterase was tested in rats 284 and completed Phase 1 human trials in 2008 for both IM and IV administration.…”
Section: B Medical Countermeasuresmentioning
confidence: 99%