In vitro skin wound soldering using SiO2/Au nanoshells and a diode laser

Khosroshahi, Mohammad E.; Nourbakhsh, Mohammad Sadegh

doi:10.1016/j.mla.2010.06.001

Cited by 10 publications

(8 citation statements)

References 36 publications

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“…Recently a variety nanomaterials including magnetite superparamagnetic iron oxide nanoparticles (SPION) and nobel metal nanoparticles such as gold have been the focus of many research fields particularly in medicine and biomedical engineering which has shown a promising advancement [1]- [3]. Plasmonic nanoparticles exhibit unique optical properties with major advantages due to the photophysical properties: strong localized surface plasmon resonance (LSPR), surface-enhanced scattering, non-linear optical properties, tunable resonance across the Vis-NIR due to adjustable nanoparticle size and shape, biocompatibility due to their inert surface, nontoxicity, surface conjugation chemistry, i.e., they can be linked to specific ligands for tumor targeting, imaging and therapies, lack of photobleaching or blinking as with quantum dots, and very low oxidation [4]- [9].…”

Section: Introductionmentioning

confidence: 99%

“…Au-NPs need surface treatment with different molecules to precisely perform desirable applications. There are some evidence of Au-NPs modification with silica, liposome and linear polymers [3] [9] [11] [12].…”

Section: Introductionmentioning

confidence: 99%

“…A fine magnetite nanoparticles with simple production method, nearly uniform size distribution and high magnetization saturation were prepared in our previous study [3] [12] [25]- [27], the optimal magnetite nanoparticles were chosen, coated with third generation PAMAM dendrimer and finally functionalized with Au-NP via different preparation methods. The main intention of the paper was to synthesize third generation dendrimers conjugated with Au-NPs using three methods of sodium borohydrate, hydrazine sulfate as the reducing agents and pre-synthesized Au-NP, and compare their fluorescent and optothermal properties with dendrimers for the purpose of biomedical application.…”

Section: Introductionmentioning

confidence: 99%

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Imaging and Therapeutic Applications of Optical and Thermal Response of SPION-Based Third Generation Plasmonic Nanodendrimers

Tajabadi¹,

Khosroshahi²,

Bonakdar³

2015

OPJ

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In this study, 9 nm superparamagnetic iron oxide nanoparticles (SPION) were functionalized by polyamidoamine (PAMAM) dendrimer. Using tetracholoroauric acid (HAuCl 4 ), magnetodendrimer (MD) samples were conjugated by gold nanoparticles (Au-NPs). Two different reducing agents, i.e. sodium borohydride and hydrazine sulfate, and pre-synthesized 10-nm Au-NP were used to evaluate the efficiency of conjugation method. The samples were characterized using X-ray diffractometry (XRD), transmission electron microscopy (TEM), Fourier transform infrared (FTIR) spectroscopy, UV-visible spectroscopy and fluorescence spectroscopy. The results confirmed that AuNPs produced by sodium borohydrate and the pre-synthesized 10-nm Au-NPs were capped by MDs whereas the Au-NP prepared by hydrazine sulfate as a reducing agent was entrapped by MDs. Optical properties of the MDs were studied by laser-induced fluorescence spectroscopy (LIF) within a wide range of visible spectrum. Also, based on the thermal analysis, all synthesized nanostructures exhibited a temperature increase using 488 nm and 514 nm wavelengths of a tunable argon laser. The new iron oxide-dendrimer-Au NPs synthesized by sodium borohydrate (IDANaBH4) produced the highest temperature increase at 488 nm whereas the other nanostructures particularly pure Au-NPs produced more heating effect at 514 nm. These findings suggest the potential application of these nanocomposites in the field of bioimaging, targeted drug delivery and controlled hyperthermia. M. Tajabadi et al.213

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Imaging and Therapeutic Applications of Optical and Thermal Response of SPION-Based Third Generation Plasmonic Nanodendrimers

Tajabadi¹,

Khosroshahi²,

Bonakdar³

2015

OPJ

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“…These free amine groups would facilitate the initial growth and the resultant growth of the nanogold. Gold nanoshells can be anattractive agents for both diagnostic and therapeutic applications [26,27]. Kim and co-workers studied a new design of magneto-plasmonic nanostructures for both MRI and photothermal therapy [28].…”

Section: Introductionmentioning

confidence: 99%

Effects of Coating and Stirring on Superparamagnetic Iron Oxide Nanoparticles Size and Magnetic Characteristics

Ghazanfari¹

2015

IJIRSET

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Considering the importance of nanoparticles physico-chemical properties in biomedical applications, we intend to describe and compares the results of fiveexperimental studies including: uncoated magnetic nanoparticles (MNPs), MNP + polyvinyl alcohol (PVA), MNP + amorphous silica (SiO 2 ) + gold (Au), and MNP + Au only. Controlled co-precipitation technique under N 2 gas is used to prevent undesirable critical oxidation of Fe 2+ .For uncoated Fe 3 O 4 NPs with saturation magnetization (M s ) range of (40-100) emu/g, smaller particles are synthesized by decreasing the NaOH concentration and increasing the stirring speed with the smallest value corresponding to 7.5 nm using 0.9 M of NaOH at 1500 rpm. The coatingprocess is done in four separate steps as follows:(i) the stable magnetic fluid containing well-dispersed Fe 3 O 4 /PVA nanocomposites which indicates a fast magnetic response with the smallest value of 7.5 nm using 0.9 M of NaOH at 750 rpm and M s of 50 emu/g, (ii) the synthesized Fe 3 O 4 NPs are stabilized using trisodium citrate (TSC) coating and then covered by SiO 2 layer using Stober method with the smallest value of 50 nm using 0.9 M of NaOH at 750 rpm and M s of 30 emu/g, (iii) small gold colloids (1-3 nm) are synthesized using Duff method and covered the amino functionalized particle surface of Fe 3 O 4 /SiO 2 nanoshells with the smallest value of 85 nm using 0.9 M of NaOH at 750 rpm and M s of 1.3 emu/g, (iv) also, bare superparamagneticIron oxide NPs (SPIONs) are covered by a thin layer of gold alone with the smallest value of 16 nm using 0.9 M of NaOH at 1500 rpm and M s of 12 emu/g. Magnetic properties and size of nanoshells are assessed using vibrating sample magnetometer (VSM)and transmission electron microscope (TEM). Furthermore, M s of 7.5 nm magnetite is high enough to be used as contrast agent for photoacoustic (PAI) and magnetic resonance imaging (MRI).

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“…Noble metal nanoparticles can be used as a biosensor [2], an exogenous absorber for laserinduced thermal therapy [3,4] or laser soldering [5]. Wavelength of plasmon resonance (λ SPR ), the extinction cross-sections, and the ratio of scattering to absorption efficiency at λ SPR are critical optical properties of noble metal nanoparticles which can be tuned by size, shape, and the dielectric properties of the surrounding medium.…”

Section: Introductionmentioning

confidence: 99%

Fabrication and Characterization of Magnetoplasmonic Liposome Carriers

Khosroshahi¹

2014

NSTOA

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In vitro skin wound soldering using SiO2/Au nanoshells and a diode laser

Cited by 10 publications

References 36 publications

Imaging and Therapeutic Applications of Optical and Thermal Response of SPION-Based Third Generation Plasmonic Nanodendrimers

Imaging and Therapeutic Applications of Optical and Thermal Response of SPION-Based Third Generation Plasmonic Nanodendrimers

Effects of Coating and Stirring on Superparamagnetic Iron Oxide Nanoparticles Size and Magnetic Characteristics

Fabrication and Characterization of Magnetoplasmonic Liposome Carriers

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