In Vitro Study of Antibacterial Activity of Mangle negro Extracts Against Selected Pathogens From Enterobacteriaceae and Bacillaceae Families

Abstract

Background: In this study, the antibacterial activity of Mangle negro extract against selected pathogens from Enterobacteriaceae and Bacillaceae was evaluated. Objectives: The antibacterial activity of M. negro ethanolic and aqueous extracts were evaluated, through disk agar diffusion method, extract on medium surface method and microdilution method. Materials and Methods: This experimental study after collection and preparation of aqueous and ethanolic extracts of M. negro, their effects against human pathogen microorganism were determined. Results: The ethanolic and aqueous extracts inhibited the growth of all the organisms tested. The minimum inhibitory concentration (MIC) of the extracts ranged between 4 mg/mL and 64 mg/mL. Conclusions: The study demonstrated that the ethanolic leaf extract of M. negro hold an excellent potential as an antibacterial agent.

Antifungal Activity of Extracts Biarum carduchorum (Kardeh) on Aspergillus fumigatus and Penicillium expansum in Vitro

“…Further trials using solvents of various polarities will explore the effects of solvent composition on extract efficacy. Alizadeh-Behbahani and Tabatabaei-Yazdi reported that most of the antimicrobial active compounds were soluble in polar solvent such as ethanol instead of water [13].…”

“…The result was obtained by measuring the zone diameter. The experiment was done three times and the mean values are presented [13].…”