In vitro study of the antioxidant, photoprotective, anti-tyrosinase, and anti-urease effects of methanolic extracts from leaves of six Moroccan Lamiaceae

Aanachi, Soukaina El; Gali, Lynda; Rammali, Said; Bensouici, Chawki; Aassila, Hinde; Dari, Khadija

doi:10.1007/s11694-020-00759-9

Cited by 22 publications

(7 citation statements)

References 78 publications

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“…The photoprotective activity was achieved following Mansur et al (1986) and El Aanachi et al (2021). The samples were prepared at a concentration of 2 mg.ml -1 diluted in absolute ethanol and then analyzed at wavelengths from 290 to 320 nm (UV) with spans of 5 nm, using ethanol as a blank.…”

Section: Photoprotective (Skin-protective) Activitymentioning

confidence: 99%

Chemical profile, antioxidant and photoprotective activities of essential oil and crude extracts of Algerian Thymus serpyllum

Madouni

Meddah

Aicha

et al. 2021

Nova Biotechnol. Chim.

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Thymus serpyllum is an aromatic and medicinal plant widely used in Algerian folk medicine. It was collected from Mascara region North West of Algeria and studied in the aim to provide more knowledge about chemical composition, antioxidant and photo-protective activities of essential oil, ethanolic and infusion extracts. The chemical analysis of investigated T. serpyllum EO was performed for the first time in this research work. It was carried out by GC/MS for identifying 25 components where the dominated compounds were Carvacrol (66%) and γ–Terpinene (11.5%). The phenolic profile of ethanolic and aqueous infusion extracts was performed using HPLC chromatography and the data showed the Benzoic acid and Rosmarinc acid were found as major compounds. Extracts showed an excellent source of total phenols and flavonoids. Antioxidant activity was evaluated using DPPH, Galvinoxyl radical (GOR), CUPRAC, reducing power and O-phenanthroline approaches. All extracts showed a significant antioxidant capacity with different mechanisms. However, ethanol and infusion extracts showed stronger capacity than EO. Moreover, the photoprotective activity of T. serpyllum extracts was explored for the first time in our study. Extracts exhibited high values of sun protective factors (SFP) with 38.34±2.29 and 38.82±2.23 for ethanol and infusion extract respectively. Results of our study may encourage the pharmacologic, food and cosmetic sectors to use the wild thyme as natural and healthy source of active compounds.

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Section: Photoprotective (Skin-protective) Activitymentioning

confidence: 99%

Chemical profile, antioxidant and photoprotective activities of essential oil and crude extracts of Algerian Thymus serpyllum

Madouni

Meddah

Aicha

et al. 2021

Nova Biotechnol. Chim.

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“…This is the first report of photoprotective activity in some Sideritis species. El Aanachi et al [ 59 ] measured the SPF of six Moroccan Lamiaceae, and found that methanolic extract of Salvia officinalis gave the highest SPF value of 39 at a concentration of 2 mg/mL, which was a concentration 10–20 times higher than those we used in our study.…”

Section: Resultsmentioning

confidence: 51%

Bioassay-Guided Skin-Beneficial Effects of Fractionated Sideritis raeseri subsp. raeseri Extract

Krgović

Jovanović

Aradski

et al. 2022

Plants

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This study aimed to evaluate the potentials for skin-beneficial effects of the hydroethanolic extract of the aerial parts of ironwort (Sideritis raeseri Boiss. & Heldr. subsp. raeseri) and its fractions (petroleum ether, ethyl acetate, n-butanol and water). For these purposes, chemical analysis and in vitro antioxidant, anti-tyrosinase and antimicrobial assays, as well as determination of sun protection factor (SPF), were performed. The highest total phenolic content and quantity of individual flavonoids, chlorogenic acid and verbascoside were determined in the n-butanol fraction, which is in line with results obtained for antioxidant activity. The greatest antimicrobial activity against Staphylococcus aureus, Staphylococcus epidermidis and Pseudomonas aeruginosa, the most common causative agents of the skin infections in humans, was exhibited by the ethyl acetate fraction. The strongest anti-tyrosinase activity was shown by the hydroethanolic extract (52.64% of inhibition at 100 μg/mL). Almost all tested samples showed photoprotective activity with SPF higher than 6 obtained at a low concentration of 0.1 mg/mL, which was more than 15 for the butanol fraction. These findings revealed that the hydroethanolic extract of S. raeseri aerial parts could be a valuable ingredient in the formulation of cosmetic and medicinal products intended to overcome various skin disorders.

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“…The overproduction of ammonia from urea, as a consequence of high urease activity leads to an increase in pH value. This promotes excellent conditions for Helicobacter pylori whose over-growth comes true, hence the progression of some stomach ailments (for example peptic ulcers, gastritis, arthritis and possibly gastric cancer) (29). Herein, the examined extracts exhibited a notable inhibitory activity against urease, with ethyl acetate extract of E. spectabilis having a higher effect.…”

Section: Discussionmentioning

confidence: 93%

Histone Deacetylase, Xanthine Oxidase and Urease Inhibitory Activities of Eremurus spectabilis M. Bieb. Extracts

Bayrak¹,

Yanardağ²

2021

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Objective: Natural ingredients derived from plants (especially edible ones) continue to be investigated for understanding whether they have therapeutic/preventive effects on certain ailments, such as cancer and gastrointestinal disorders. The main goal of the current work is to investigate the inhibitory potential of Eremurus spectabilis M. Bieb. extracts on histone deacetylase (HDAC), xanthine oxidase (XO) and urease activities.Material and Method: Fresh E. spectabilis leaves were obtained from a local market in Eyup/Istanbul. Inhibitory activities of ethanolic and ethyl acetate extracts on HDAC, XO and urease were examined.Results: According to our findings, ethanolic and ethyl acetate extracts of E. spectabili both have revealed apparent inhibitory effects against all examined enzymes. Ethanolic extract showed a better inhibitory effect on HDAC than ethyl acetate extract. On the other hand, the inhibitory effects of ethyl acetate extract against both XO and urease were higher than the ethanolic extract. Conclusion:Consequently, due to the inhibitory effects of the plant being studied, it might be suggested that it can be used for medicinal purposes, in raw extract form, or as a source of bioactive compounds.

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In vitro study of the antioxidant, photoprotective, anti-tyrosinase, and anti-urease effects of methanolic extracts from leaves of six Moroccan Lamiaceae

Cited by 22 publications

References 78 publications

Chemical profile, antioxidant and photoprotective activities of essential oil and crude extracts of Algerian Thymus serpyllum

Chemical profile, antioxidant and photoprotective activities of essential oil and crude extracts of Algerian Thymus serpyllum

Bioassay-Guided Skin-Beneficial Effects of Fractionated Sideritis raeseri subsp. raeseri Extract

Histone Deacetylase, Xanthine Oxidase and Urease Inhibitory Activities of Eremurus spectabilis M. Bieb. Extracts

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