In-vitro- und In-vivo-Untersuchungen zur Presbyopiebehandlung mit Femtosekundenlasern

Gerten, Georg; Ripken, Tammo; Breitenfeld, P.; Krueger, R.R.; Kermani, Omid; Lubatschowski, Holger; Oberheide, Uwe

doi:10.1007/s00347-006-1400-1

Cited by 23 publications

(7 citation statements)

References 38 publications

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“…Early in vivo studies with New Zealand White rabbits have shown that there was no cataract formation within three months [16]. Additionally, no scattering or haze was observed by Krueger and Gerten et al [7].…”

Section: Discussionmentioning

confidence: 92%

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fs-Laser induced elasticity changes to improve presbyopic lens accommodation

Ripken

Oberheide²,

Fromm

et al. 2007

Graefes Arch Clin Exp Ophthalmol

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Section: Discussionmentioning

confidence: 92%

“…In a previous study, we have shown with Krueger et al [7,16] that after cutting inside rabbit crystalline lens tissue in vivo the lens stays clear for at least 3 months. In six treated eyes, no cataract due to the laser procedure occurred, and the 3-month post-op showed good transparency for all eyes.…”

Section: Introductionmentioning

confidence: 94%

fs-Laser induced elasticity changes to improve presbyopic lens accommodation

Ripken

Oberheide²,

Fromm

et al. 2007

Graefes Arch Clin Exp Ophthalmol

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“…Because of the bilaterality of occurrence, this appears to be unrelated to the laser treatment. 19,20 This study shows the technological progress of the first 100 kHz laboratory fs-Lentotomy laser unit and the first in vivo results of treated rabbit lenses with this unit.…”

Section: Scanning Mirrnrsmentioning

confidence: 96%

Fs-lentotomy: first in vivo studies on rabbit eyes with a 100 kHz laser system

Schumacher

Oberheide²,

Fromm

et al. 2008

SPIE Proceedings

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Up to now reading glasses are the conventional treatment of presbyopia, an age related effect for every human. According to the Helmholtz theory the reason for the development of accommodative loss is a decreasing elasticity of the lens due to the increasing sclerosis. Since the ciliary muscle and the lens capsule remain active and elastic the whole life, a possible treatment could be the increase of the flexibility by creating gliding planes with fs-laser pulses.In former studies it was shown that fs-laser pulses can increase the flexibility of ex vivo porcine as well as human donor lenses with a laboratory laser system. We will present new results with a compact 100 kHz repetition rate turn key laser system which speeds up the treatment time by a factor of 10. This will offer the opportunity for future clinical trials. Furthermore first in-vivo results on rabbits are presented.

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“…1,2 With growing interest in presbyopia correction, 3,4 several surgical methods were developed to provide near visual acuity without spectacles in presbyopic phakic eyes 5,6 and pseudophakic eyes. 2,[7][8][9][10] Several new IOL optic designs have been proposed for pseudophakic eyes.…”

mentioning

confidence: 99%