In vivo analysis of the iris thickness by spectral domain optical coherence tomography

Abstract

SD-OCT is a suitable technique for iris thickness assessment. Thickness analysis must be carried out using a sectorial approach, taking into consideration anatomical variations existing between different iris regions. SD-OCT is a potentially useful tool for detecting iris thickness variations induced by pathological conditions such as Fuchs' uveitis.

Authors’ reply to: Using anterior segment optical coherence tomography to compare the smoothness of anterior iris surface between two eyes in unilateral Fuchs’ uveitis syndrome

“…However, the decision on diffuse atrophy existence in this study has been made by observation not based on quantitative analysis. The studies that conducted for analysis of iris thickness of FUS quantitatively have shown decreased iris thickness (IT) in the affected eye compared with the healthy fellow eye [3,4]. In our study, we could not have found a statistically significant difference between the IT of both eyes having unilateral FUS, and we concluded that this might be due to racial differences in iris morphology or patient selection.…”

Numerical model to predict and compare the hypotensive efficacy and safety of minimally invasive glaucoma surgery devices

“…For the elimination of AH, we only considered the trabecular route because this is the main drainage route (accounting for 90% of elimination of AH) [16]; the uveoscleral route was not simulated. Variables included in the simulation were based on standard values for an adult human eye [16,[25][26][27][28][29][30][31][32] (Table 2). The numerical procedure was the same as described by Fernandez-Vigo et al [33] and Agujetas et al [34].…”

Optical coherence tomography and optical coherence tomography angiography in uveitis: A review

“…Mahendradas et al described the use of AS‐OCT to monitor the response to treatment of an iris granuloma in a patient with leprosy. Independent groups reported a thinning of the iris assessed through OCT scans in patients with Fuchs uveitis . Finally, AS‐OCT can be used to evaluate the presence of posterior synechia (Figure C) or peripheral anterior synechia in uveitic patients and help in assessing the risk to develop angle closure glaucoma …”

“…Independent groups reported a thinning of the iris assessed through OCT scans in patients with Fuchs uveitis. 24,25 Finally, AS-OCT can be used to evaluate the presence of posterior synechia ( Figure 6C) or peripheral anterior synechia in uveitic patients and help in assessing the risk to develop angle closure glaucoma. 26 In AU, the inflammatory process is mainly localized in the anterior chamber; nevertheless, recent evidence suggests that the choroidal blood flow may also be affected.…”