“…Various detoxification and sequestration mechanisms have been identified, such as incorporation into calcium concretions ), binding to 6 metallothionein-like low molecular weight proteins (Accomando et al 1990) and Immobilization In phagolysosomes (Coombs and George 1978 (Sunila , 1988; (2) for digestive glands, changes In epithelial structure, vacuolization and accumulation of lipids in digestive and basophil cells ; (3) for the kidneys, ultrastructural changes including swollen mitochondria and reduced glycogen reserves (Hemeiraad et al 1990);…”