“…1 Besides polymers or ceramic-based biocompatible materials, either as single phases or composites, [2][3][4][5][6][7][8][9] bone autografts, allografts, or xenografts have also been suggested as structural support (scaffolds) to repair or regenerate diseased bone. [10][11][12][13][14][15][16][17][18][19][20][21] Advantages and disadvantages of decellularized bone for its use as TE scaffold have been discussed in the literature. 11,[16][17][18][19] Because of its three-dimensional (3D) microstructure and morphology (i.e., highly interconnected and permeable structure with high porosity), its natural nanoscale topography and hierarchical structure, biochemical composition, and suitable mechanical properties and structural environment, decellularized trabecular bone provides an adequate ''biomimetic'' scaffold/matrix that should enable cells to attach, proliferate, differentiate, and organize into healthy bone.…”