In vivo digital imaging of the square-edged barrier effect of a silicone intraocular lens

Abstract

Early contact inhibition of LECs by a square-edged IOL design and its effects were demonstrated in vivo with sequential, high-resolution digital photography and commercially available graphics software.

Evaluating and defining the sharpness of intraocular lenses: Microedge structure of commercially available square-edged hydrophilic intraocular lenses

“…[1][2][3][4][5] Tetz and Wildeck 6 made the first attempt to evaluate and quantify the edge structure of IOLs at the microscopic level. They experimentally evaluated the optimum microedge profile of an IOL to prevent lens epithelial cell (LEC) migration in culture.…”

Three-hundred-sixty degree barrier effect of a square-edged and an enhanced-edge intraocular lens on centripetal lens epithelial cell migration

“…A more recent study based on similar digital photographs found a ''damming'' effect to migrating LECs at the square posterior edge at 1 month. 13 Our study was an objective assessment of LEC migration in relation to the square edge and enhanced edge of the optic. We put forward criteria by which these changes can be graded by digital photography.…”

Pattern of posterior capsule opacification models 2 years postoperatively with 2 single-piece acrylic intraocular lenses

“…Early studies of cadaver eyes 4 found that IOLs with a truncated (squared) posterior optic edge provided a barrier to LEC migration along the posterior capsule. Since then, several studies [5][6][7] have confirmed that a sharp capsular bend formed when the capsule wraps around the sharp posterior edge of a square-edged IOL inhibits LEC migration, thus limiting the development of PCO.…”