In vivo effect of antibacterial and fluoride-releasing adhesives on enamel demineralization around brackets: A micro-CT study

Oz, Aslihan Zeynep; Öz, Abdullah Alper; Yazıcıoğlu, Sabahat

doi:10.2319/060217-371.1

Cited by 15 publications

(11 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It found no significant differences among the adhesives regarding either the volume or depth of the WSLs. The results of the present study, which was long-term, were similar results to those of this short-term in vivo study [22].…”

Section: Discussionsupporting

confidence: 89%

Effectiveness of an antibacterial primer used with adhesive-coated brackets on enamel demineralization around brackets: an in vivo study

Öz

Yazıcıoğlu

et al. 2019

Prog Orthod.

Self Cite

View full text Add to dashboard Cite

Background The aim of the study is to assess the clinical effect of an antibacterial monomer-containing primer on preventing white spot lesions (WSLs) during fixed orthodontic treatment. Subject and methods The study included 35 patients. A split-mouth design was used during bonding of the brackets. In Clearfil (CF) group, adhesive-coated brackets (APC Plus Victory series, 3M Unitek, Monrovia, CA, USA) were bonded with an antibacterial monomer-containing primer (Clearfil Protect Bond, Kuraray Medical, Okayama, Japan). In Transbond (TB) group, the same adhesive-coated brackets were bonded using a conventional primer (Transbond XT Primer; 3M Unitek, Monrovia, CA, USA). The mean duration of orthodontic treatment was 16 months. Digital images of each tooth were used to assess the WSLs. The areas of the WSLs were measured with a software. The bond failures during orthodontic treatment were also recorded. Results After fixed orthodontic treatment, 23 of the 35 patients showed one or more WSLs. Of the total of 666 teeth, 114 WSLs occurred over the orthodontic treatment time. Rates of WSL in the CF and TB groups were 8.03% and 9.24%, respectively. The difference in WSL rates between the two groups was not statistically significant. No significant difference was observed in the lesion areas between the groups. Moreover, the difference in bracket failure rates between the two groups was also not statistically significant. Conclusion The results of this long-term clinical study indicated no significant difference between the antibacterial monomer-containing primer group and the control group in the efficacy of reducing demineralization throughout the orthodontic treatment.

show abstract

Section: Discussionsupporting

confidence: 89%

Effectiveness of an antibacterial primer used with adhesive-coated brackets on enamel demineralization around brackets: an in vivo study

Öz

Yazıcıoğlu

et al. 2019

Prog Orthod.

Self Cite

View full text Add to dashboard Cite

show abstract

“…Although glass ionomer cements containing fluoride have been used as orthodontic adhesives, their bracket retention force is relatively low compared with that of conventional resin bonding [9]. Furthermore, studies on existing commercial fluoride-releasing adhesives and glass ionomers have revealed that they do not demonstrate a significant advantage in terms of their anti-demineralization effects compared with products that do not release fluoride [10]. To overcome these drawbacks, resin-modified glass-ionomer cements (RMGICs) have become the subject of various studies.…”

Section: Introductionmentioning

confidence: 99%

Fluorinated Bioactive Glass Nanoparticles: Enamel Demineralization Prevention and Antibacterial Effect of Orthodontic Bonding Resin

et al. 2019

View full text Add to dashboard Cite

Orthodontic treatment involving the bonding of fixed appliances to tooth surfaces can cause white spot lesions (WSLs). WSLs increase the likelihood of cavity formation and hence require preservation and prosthetic restoration. Therefore, the prevention of WSLs is of greater importance than treatment. Application of fluoride or the use of fluoride-containing mouthwash can prevent WSLs, but this requires patient cooperation and additional time and cost. Bioactive glass containing 2.5% fluoride was synthesized and mixed with the orthodontic bonding adhesive Transbond XT Low Flow (LV) at ratios of 1, 3, and 5% to prepare orthodontic adhesive samples. Scanning electron microscopy (SEM) and X-ray diffraction (XRD) were used to characterize the samples. The Vickers hardness test, bracket retention test, and adhesive remnant index (ARI) of the samples were analysed to determine their mechanical properties. To determine the biological cytotoxicity, the cell activity of the samples was evaluated using cell viability tests and the antibacterial activity was analysed using Streptococcus mutans. To evaluate the anti-demineralization effect, the sample was bonded to extracted teeth and a pH cycle test was performed. Micro computed tomography data were obtained from the bonded teeth and sample, and the anti-demineralization effect was evaluated using the ImageJ software program. The Vickers hardness of the sample was higher than that of LV and was dependent on the concentration of fluoride-containing bioactive glass (FBAG). The bracket retention test and ARI of the sample showed no significant differences from those of LV. The cell viability test showed no significant changes at 24 and 48 h after application of the sample. The fluoride ion release test indicated an ion release rate of 9.5–17.4 μg/cm2. The antibacterial activity of the experimental group containing FBAG was significantly higher than that of the LV group. The anti-demineralization test showed a concentration-dependent increase. However, the resin containing 5 mass% FBAG (FBAG5) showed a statistically-significant increase compared with LV. The orthodontic adhesive containing FBAG showed antibacterial and anti-demineralization effects, thus indicating possible WSL prevention activity.

show abstract

“…4 In recent years, new adhesives and primers that contain and release fluoride have entered the orthodontic market. 7,8 Previous studies showed that these fluoride-containing glass ionomer and composite adhesives decrease enamel decalcification around orthodontic brackets. 9,10 However, the fluoridecontaining and releasing adhesives and primers show their highest levels during the first weeks after bracket bonding.…”

mentioning

confidence: 99%

Clinical effect of a fluoride-releasing and rechargeable primer in reducing white spot lesions during orthodontic treatment

Comert

Öz

2020

American Journal of Orthodontics and Dentofacial Orthopedics

Self Cite

View full text Add to dashboard Cite

This study was performed to test the long-term efficacy of a highly filled resin primer (38%) that has superior fluoride release and recharge ability. Methods: Sixty patients were divided into 2 groups. In group 1, adhesive-coated brackets (APC Plus Victory series, 3M Unitek, Monrovia, Calif) were bonded with a fluoridereleasing and rechargeable primer (Opal Seal; Ultradent, South Jordan, Utah). In group 2, the same adhesive-coated brackets were bonded with a conventional primer (Transbond XT Primer; 3M Unitek, Monrovia, Calif). In group 1, a blacklight source was used to examine the amount of adhesive remaining on enamel surfaces. This primer has a fluorescing agent and fluoresces under blacklight. If there was a lack of primer on any part of the enamel surrounding the brackets, new primer was added. Digital images of each tooth were taken to score and measure the area of white spot lesions (WSLs) after orthodontic treatment. DIAGNOdent (DIAGNOdent pen; KaVo Dental, Biberach, Germany) measurements were also used to assess WSLs after bracket removal. Results: The WSL rate was 26.9% for group 1 and 29% for group 2. There was no significant difference between the WSL scores of the groups; however, a significant difference was observed in the DIAGNOdent measurements between the groups. According to area measurements of the lesions, there was no significant difference between the groups. Conclusions: The results of this long-term clinical study indicated that fluoride-releasing primer has no significant advantage in reducing demineralization over the control primer over the full orthodontic treatment period.

show abstract

In vivo effect of antibacterial and fluoride-releasing adhesives on enamel demineralization around brackets: A micro-CT study

Cited by 15 publications

References 23 publications

Effectiveness of an antibacterial primer used with adhesive-coated brackets on enamel demineralization around brackets: an in vivo study

Effectiveness of an antibacterial primer used with adhesive-coated brackets on enamel demineralization around brackets: an in vivo study

Fluorinated Bioactive Glass Nanoparticles: Enamel Demineralization Prevention and Antibacterial Effect of Orthodontic Bonding Resin

Clinical effect of a fluoride-releasing and rechargeable primer in reducing white spot lesions during orthodontic treatment

Contact Info

Product

Resources

About