2013
DOI: 10.1016/j.anireprosci.2013.09.003
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In vivo effects of Trichostatin A – A histone deacetylase inhibitor – On chromatin remodeling during Triturus cristatus spermatogenesis

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Cited by 14 publications
(20 citation statements)
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“…The most common methods for genotoxicity testing on amphibians to detect DNA damage are chromosome aberration assays, micronucleus assays, sister chromatid exchange assays, and so-called comet assays (single cell gel electrophoresis) (120). More recent approaches, including chromatin immunoprecipitation, have provided important insights into epigenetic alterations in male crested newt (Triturus cristatus) spermatogenesis owing to environmental exposures (148); additional research on other taxa would be a welcome addition to our understanding of toxicological exposure in amphibians. Comet assays, which visualize breaks in denatured DNA, have also been used to analyze genotoxicological effects in reptiles and amphibians to a limited extent.…”
Section: Ecotoxicology and Genotoxicologymentioning
confidence: 99%
“…The most common methods for genotoxicity testing on amphibians to detect DNA damage are chromosome aberration assays, micronucleus assays, sister chromatid exchange assays, and so-called comet assays (single cell gel electrophoresis) (120). More recent approaches, including chromatin immunoprecipitation, have provided important insights into epigenetic alterations in male crested newt (Triturus cristatus) spermatogenesis owing to environmental exposures (148); additional research on other taxa would be a welcome addition to our understanding of toxicological exposure in amphibians. Comet assays, which visualize breaks in denatured DNA, have also been used to analyze genotoxicological effects in reptiles and amphibians to a limited extent.…”
Section: Ecotoxicology and Genotoxicologymentioning
confidence: 99%
“…The eruption vices of the mandibular wisdom tooth can cause a further imbalance factor within the dento-maxillary system, through the pushing process of the 12-year-old molar towards mesial. Thus, taking into account all the possibilities of negatively influencing the relationship between the constituents of this dento-maxillary system produced by the wisdom tooth, it is mandatory to monitor the position of the germs and their possibility of eruption in rela-tion to what is found mesial of them (1)(2)(3)(4)(5)(6)(7)(8). The distalization of mandible, which is seen as the most frequent dimensional change, is aggravated by odontal pathology (1)(2)(3)(4)(5).…”
Section: Methodsmentioning
confidence: 99%
“…Correct answers: a, b. 6. How do you think the orthodontist should intervene in dento-alveolar disharmonies in patients over the age of 12 years: a.…”
Section: The Age After 12 Years Is the Time When The Resistance Of Thmentioning
confidence: 99%
“…In the case of the 6-year molar edentation, regardless of its location mandibular and/or maxillary, the fastest treatment is to obtain conventional prosthetic restorations. These can be accomplished in a shorter time, but require preparing of neighboring teeth, and in most cases root canal treatment (1)(2)(3)(4)(5)(6)(7)(8).…”
Section: Purposementioning
confidence: 99%