In Vivo Evaluation of Lung Microwave Ablation in a Porcine Tumor Mimic Model

Planché, O.; Tériitéhau, C.; Boudabous, Sana; Robinson, Joey Marie; Rao, Pramod; Deschamps, Frédèric; Farouil, Geoffroy; Baère, Thierry De

doi:10.1007/s00270-012-0399-8

Cited by 44 publications

(32 citation statements)

References 31 publications

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“…Compared to RFA, less research is available on MWA, but it is a promising option because it offers larger ablation zones, reduced procedure times, and decreased heat‐sink effects . In our study, we focused on a comparison of RFA and MWA for the treatment of lung tumors.…”

Section: Discussionmentioning

confidence: 99%

Comparison study of computed tomography‐guided radiofrequency and microwave ablation for pulmonary tumors: A retrospective, case‐controlled observational study

et al. 2018

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BackgroundThe aim of this study was to compare the safety, efficacy, and prognostic value of radiofrequency ablation (RFA) and microwave ablation (MWA) for lung tumors.MethodsBetween March 2012 and January 2018, 238 patients with lung cancer were treated with MWA (139, 58.4%) or RFA (99, 41.6%) in our center. Patient and tumor characteristics, complications, complete ablation (CA) rate, and prognosis were compared between the groups. Meta‐analysis was used to systematically compare the outcomes of RFA and MWA for the treatment of lung tumors.ResultsAblation was successfully completed in all patients and no procedure‐related death occurred. The total complication rates in the RFA and MWA groups were 24.2% (24/99) and 16.5% (23/139), respectively, and there was no statistically significant difference (P = 0.142). The initial and total CA rates were similar at P > 0.05 (RFA vs. MWA: initial CA, 97.0% vs. 96.4%; total CA, 99.0% vs. 98.6%, respectively). During follow‐up, there was no significant difference in median progression‐free (RFA vs. MWA: 12.5 months, 95% confidence interval [CI] 5.002–19.998 vs. 9.5 months, 95% CI 6.623–12.377; P = 0.673) or overall survival (RFA vs. MWA: 33 months, 95% CI 27.070–38.930 vs. 30 months, 95% CI, 18.482–41.518; P = 0.410) between the groups. Combined with the results of published comparison studies, meta‐analysis further confirmed that the outcomes of these two treatments were similar.ConclusionBoth RFA and MWA are safe and effective treatments with a survival benefit for selected patients with primary and metastatic lung tumors.

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Section: Discussionmentioning

confidence: 99%

Comparison study of computed tomography‐guided radiofrequency and microwave ablation for pulmonary tumors: A retrospective, case‐controlled observational study

et al. 2018

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“…This fact renders the heat produced by RFA vulnerable to being washed out by vessels as small as 3 mm, a phenomenon known as the heat sink effect [35,36]. In contrast, MWA, whose heating deposition ability is favored by the presence of water, has been proven to be less susceptible to the heat sink effect by inducing complete thrombosis of most vessels with a diameter < 6 mm [37,38].…”

Section: Advantages Of Microwave Ablationmentioning

confidence: 99%

“…The postprocedural evolution of the ablation zone is usually divided into three continuous phases with corresponding histologic and imaging findings [55 -57]. The features of the thermally ablated lung tissue have first been described after RFA, but are similar to those after MWA [37,38].…”

Section: Imaging Follow-upmentioning

confidence: 99%

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Thermal Ablation of Lung Tumors: Focus on Microwave Ablation

Vogl

Nour-Eldin

Albrecht

et al. 2017

Fortschr Röntgenstr

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“…In a recent paper it was shown that MWA has less heat sink effect: in models a single MWA antenna can create ablation zones large enough to cover lung tumor of <4 cm diameter with no heat sink effect for vessels up to 6 mm (22). In clinical practice the advantage of the method MWA lies in faster reaching therapeutic temperatures, applicable higher temperatures, and faster ablation.…”

Section: Mwa Versus Rfamentioning

confidence: 99%

From diagnosis to therapy in lung cancer: management of CT detected pulmonary nodules, a summary of the 2015 Chinese-German Lung Cancer Expert Panel

Meyer

Pirker

et al. 2016

Transl. Lung Cancer Res.

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Improved risk classification criteria and novel imaging approaches for screening populations are highly required as more than half of lung cancer cases are false positive during the initial screening round if the National Lung Screening Trial (NLST) demographic criteria [≥30 pack years (PY) of cigarettes, age ≥55 years] are applied. Moreover, if the NLST criteria are applied to the Chinese population a high number of lung cancer patients are not diagnosed due to non-smoking related risk factors in China. The primary goal in the evaluation of pulmonary nodules (PN) is to determine whether they are malignant or benign. Volumetric based screening concepts such as investigated in the Dutch-Belgian randomized lung cancer screening trial (NELSON) seem to achieve higher specificity. Chest CT is the best imaging technique to identify the origin and location of the nodule since 20% of suspected PN found on chest X-ray turn out to be non-pulmonary lesions. Moreover, novel state-of-the-art CT systems can reduce the radiation dose for lung cancer screening acquisitions down to a level of 0.1 mSv with improved image quality to novel reconstruction techniques and thus reduce concerns related to chest CT as the primary screening technology. The aim of the first part of

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In Vivo Evaluation of Lung Microwave Ablation in a Porcine Tumor Mimic Model

Cited by 44 publications

References 31 publications

Comparison study of computed tomography‐guided radiofrequency and microwave ablation for pulmonary tumors: A retrospective, case‐controlled observational study

Comparison study of computed tomography‐guided radiofrequency and microwave ablation for pulmonary tumors: A retrospective, case‐controlled observational study

Thermal Ablation of Lung Tumors: Focus on Microwave Ablation

From diagnosis to therapy in lung cancer: management of CT detected pulmonary nodules, a summary of the 2015 Chinese-German Lung Cancer Expert Panel

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