In vivo topical anti-inflammatory and wound healing activities of the fixed oil of Caryocar coriaceum Wittm. seeds

Oliveira, Maria Liduína Maia de; Nunes-Pinheiro, Diana Célia Sousa; Tomé, Adriana R.; Mota, Érika Freitas; Lima-Verde, Islene Araújo; Pinheiro, Francisco Geraldo de Melo; Campello, C.C.; Morais, Selene Maia de

doi:10.1016/j.jep.2010.03.014

Cited by 53 publications

(50 citation statements)

References 23 publications

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“…The fatty acid profiles of C. coriaceum and C. villosum pulps are similar to those observed for C. brasiliense (Saraiva et al, 2011a;De Oliveira et al, 2010;Da Silva Quirino et al, 2009;Marx et al, 1997;Figueiredo et al, 1989). In addition, C. coriaceum almonds have a similar oleic and palmitic acid-rich composition (Table 1) (De Oliveira et al, 2010;Figueiredo et al, 1989).…”

Section: Fatty Acidssupporting

confidence: 81%

“…In addition, the almond seems to contain more protein (80%) and minerals (80%) ( Table 1) (Macedo et al, 2011;Lima et al, 2007) and is rich in Mg (452.1 mg/100 g), selenium (Se) (0.0014 mg/100 g), and Zn (Faria-Machado et al, 2015;Macedo et al, 2011;Garcia et al, 2007;Lima et al, 2007;Vera et al, 2007;Facioli and Gonçalves, 1998); b (Torres et al, 2016b;Faria-Machado et al, 2015;Macedo et al, 2011;Lima et al, 2007); c (Ramos and Souza, 2011;Saraiva et al, 2011a;Oliveira et al, 2010;Da Silva Quirino et al, 2009;Figueiredo et al, 1989); d (Ramos and Souza, 2011;De Oliveira et al, 2010;Oliveira et al, 2010;Figueiredo et al, 1989); e Marx et al, 1997); n.a .…”

Section: Nutritional Compositionmentioning

confidence: 99%

“…According to De Oliveira et al (2008), several species of the genus Caryocar are known as pequi and other derivatives such as piqui, piquiá, and piqui-vinagreiro. However, other authors describe pequi as a popular denomination for the fruits of C. brasiliense, which grows in the Central-West Region of Brazil and the western part of the state Minas Gerais; while "piqui" would be considered the fruits of C. coriaceum, which grows in northeastern Brazil; and "pequiá" the fruits of C. villosum, which grows in the Amazon Region (Geocze et al, 2013;Costa et al, 2011;De Oliveira et al, 2010;Lima et al, 2007;Segall et al, 2006;Marx et al, 1997). These three species represent the main source of income for many small communities in Brazil (Leite et al, 2017;Guedes et al, 2017;Figueiredo et al, 2016;Costa et al, 2011;De Moraes Cardoso et al, 2013;Marx et al, 1997).…”

Section: Introductionmentioning

confidence: 99%

“…tumors, respiratory diseases, wound lesions, gastric and inflammatory diseases, muscle pain, and chronic arthritis (Miranda-Vilela et al, 2014;Costa et al, 2011;Da Silva Quirino et al, 2009;MirandaVilela et al, 2008). Pequi presents some beneficial biological properties, such as wound-healing and anti-inflammatory activities, antimicrobial activity, and protection against genomic and oxidative damage, among others (Colombo et al, 2015;Costa et al, 2011;De Oliveira et al, 2010;Da Silva Quirino et al, 2009;Passos et al, 2002). These biological properties, along with the nutritional and health benefits, are mainly attributed to the presence of monounsaturated fatty acids (MUFA) and phytochemicals (Aguilar et al, 2011;Roesler et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

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Bioactive compounds and functional potential of pequi (<em>Caryocar</em> spp.), a native Brazilian fruit: a review

et al. 2018

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SUMMARY:Pequi is an indigenous word that means "thorny covering" and is used to describe fruits from the Caryocar spp. These fruits are widely consumed as food and used in traditional medicine by Brazilians in the savannah (Cerrado biome) and the Amazon region. The fruit is rich in lipids, mainly oleic acid, and other bioactive substances including carotenoids, phenolics, and tocopherols. The oil extracted from the pulp or "almond" (seed) has a high local socioeconomic impact and is associated with nutritional and therapeutic benefits. A wide array of health benefits such as antioxidant, anti-inflammatory, antitumor, and antimicrobial effects, improved cardiac function, as well as an increased lymphocyte-dependent immunity have been attributed to the pequi fruit, especially its pulp. This review provides a comprehensive overview on the edible parts of pequi fruits (pulp and almond), more specifically the oil produced from these parts, as a source of functional compounds with biological activity. Moreover, it considers the differences among the three more commercially-important species from the genus Caryocar. KEYWORDS: Bioactive compounds; Caryocaraceae; Fruit; Health benefits; Oleic acid RESUMEN:Compuestos bioactivos y funcionalidad potencial del pequi (Caryocar spp.), fruta nativa brasileña. Revisión. Pequi es una palabra indígena que significa "piel espinosa" y es utilizada para describir los frutos de Caryocar spp. Estos frutos son ampliamente consumidos como alimentos y son utilizados en la medicina popular por los brasileños ubicados en el Savannah (bioma Cerrado) y en la región amazónica. La fruta es rica en grasas, ácido oleico y otros bioactivos, incluyendo carotenoides, fenoles y tocoferoles. El aceite procedente de la pulpa o de la almendra (semilla) tiene un importante impacto socioeconómico local y está asociado con beneficios nutricionales y terapéuticos. Una amplia gama de beneficios para la salud tales como antioxidante, antiinflamatorio, antitumoral, antimicrobiano, mejora de la función cardíaca, así como el aumento de la inmunidad linfocitaria han sido atribuidas a la fruta, especialmente a su pulpa. Esta revisión proporciona una descripción exhaustiva sobre las partes comestibles de la fruta del pequi (pulpa y almendra), más específicamente del aceite producido a partir de estas partes, como una fuente de compuestos funcionales con actividad biológica. Además se consideran las diferencias encontradas entre las tres especies comerciales más importantes del género Caryocar.

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Section: Fatty Acidssupporting

confidence: 81%

Section: Nutritional Compositionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Bioactive compounds and functional potential of pequi (<em>Caryocar</em> spp.), a native Brazilian fruit: a review

et al. 2018

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“…Male Swiss mice weighing 25-30 g were individually housed in clean polyethylene cages under standard experimental conditions of humidity (40-45%), temperature (23)(24)(25) C), light/dark cycle (12 h), and fed on normal pellet diet and water ad libitum. All animal experiments were carried out in accordance with the guidelines for the ethical use of experimental animals published by the Brazilian National Council for the Control of Animal Experimentation.…”

Section: Animalsmentioning

confidence: 99%

Anti-inflammatory and wound healing potential of cashew apple juice (Anacardium occidentale L.) in mice

Vasconcelos

Gomes-Rochette

Oliveira

et al. 2015

Exp Biol Med (Maywood)

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Cashew apple is a tropical pseudofruit consumed as juice due to its excellent nutritional and sensory properties. In spite of being well known for its important antioxidant properties, the cashew apple has not been thoroughly investigated for its therapeutic potential. Thereby, this study evaluated the antioxidant capacity, anti-inflammatory, and wound-healing activities of cashew apple juice. Juices from ripe and immature cashew apples were analyzed for antioxidant, anti-inflammatory, and wound-healing properties. Those were evaluated in murine models of xylene-induced ear edema and wound excision. Swiss mice were treated with cashew juice by gavage. Edema thickness was measured and skin lesions were analyzed by planimetry and histology. Both antioxidant content and total antioxidant activity were higher in ripe cashew apple juice (RCAJ) than in unripe cashew apple juice (UNCAJ). The UNCAJ presented the main anti-inflammatory activity by a significant inhibition of ear edema (66.5%) when compared to RCAJ (10%). Moreover, UNCAJ also showed the best result for wound contraction (86.31%) compared to RCAJ (67.54%). Despite of higher antioxidant capacity, RCAJ did not promote better anti-inflammatory, and healing responses, which may be explained by the fact that treatment increased antioxidants level leading to a redox ''imbalance'' turning down the inflammatory response modulation exerted by reactive oxygen species (ROS). The results suggest that UNCAJ presents a greater therapeutic activity due to a synergistic effect of its phytochemical components, which improve the immunological mechanisms as well as an optimal balance between ROS and antioxidants leading to a better wound healing process.

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Potential of Oilseeds Native to Amazon and Brazilian Cerrado Biomes: Benefits, Chemical and Functional Properties, and Extraction Methods

Cornelio-Santiago

Bodini

Oliveira

2020

J Americ Oil Chem Soc

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The primary objective of this study was to shed greater light on the characteristics and multifaceted potential of oil extracts from kernels of Bertholletia excelsa (Brazil nut), seeds of the Plukenetia species and Caryocar species. These are but a few of the multitude of the plant species found in the Amazon and Brazil's Cerrado biomes. They have many substantial organoleptic, nutritional, and functional properties that are comparable or exceed better known oils, and they manifest health benefits and prospective economic opportunities as an oil source for foods, pharmaceutical, and cosmetic industries. It is also hoped that this study gives rise to further research that may be beneficial to the industry and improve the local economies where these raw materials are found.

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In vivo topical anti-inflammatory and wound healing activities of the fixed oil of Caryocar coriaceum Wittm. seeds

Cited by 53 publications

References 23 publications

Bioactive compounds and functional potential of pequi (<em>Caryocar</em> spp.), a native Brazilian fruit: a review

Bioactive compounds and functional potential of pequi (<em>Caryocar</em> spp.), a native Brazilian fruit: a review

Anti-inflammatory and wound healing potential of cashew apple juice (Anacardium occidentale L.) in mice

Potential of Oilseeds Native to Amazon and Brazilian Cerrado Biomes: Benefits, Chemical and Functional Properties, and Extraction Methods

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