Background: Lumbosacral transitional vertebrae (LSTV) are a relatively common variant and have
been considered as one of the reasons for back pain. It is not unusual for clinicians to encounter
patients with LSTV who require caudal epidural block (CEB) for pain management.
Objective: We investigated the termination level of the dural sac (DS) and anatomical features
of the lumbosacral region relevant to CEB in patients with LSTV and compared these findings
between sacralization and lumbarization groups.
Study Design: A retrospective evaluation.
Setting: A university hospital with inpatient and outpatient LSTV cases presenting low back pain.
Methods: Four hundred ninety-four LSTV patients were included and categorized into sacralization
(n = 201) or lumbarization groups (n = 293). Magnetic resonance imaging (MRI) of all of the LSTV
patients were reviewed to determine the level of DS termination, the shortest distance between
the apex of the sacral hiatus and DS, and the presence and the caudal level of sacral perineural
cysts. Each lumbosacral vertebra column was divided into 3 equal portions (upper, middle, and
lower thirds). The MRI findings in both of the groups were compared and analyzed.
Results: The distribution frequency of the levels of DS termination demonstrated a significant
difference between the 2 groups. The mean caudal DS level in the lumbarization group was
significantly lower than the sacralization group (lower third of the S2 [131 {44.7%} of 293 patients]
vs. lower third of the S1 [78 {38.8%} of 201 patients]). The DS terminated at the S3 in more than
19% of the lumbarization group, whereas in only one case of the sacralization group. Although
the incidence of perineural cysts was not significantly different between the 2 groups, the mean
level of caudal margin of perineural cysts in the lumbarization group was significantly lower than
the sacralization group (middle third of the S3 [10 {35.7%} of 28 cases] vs. middle third of the S2
[11 {44%} of 25 cases]).
Limitations: This study reveals several limitations including the practical challenge of accurate
enumeration of the transitional segment and the constraints on generalizability posed by the
single-country study.
Conclusion: When planning CEB for patients with LSTV, pre-procedural MRI to check the
anatomical structures, including the level of DS termination and caudal margin of perineural cysts,
would be of great use for lowering the risk of unexpected dural puncture during the procedure,
especially in the lumbarization cases.
Key words: Termination of the dural sac, dural sac termination, lumbosacral transitional
vertebrae, transitional vertebra, caudal epidural block