Incidence and survival of sebaceous carcinoma in the United States

Tripathi, Raghav; Chen, Zhengyi; Li, Li; Bordeaux, Jeremy S.

doi:10.1016/j.jaad.2016.07.046

Cited by 86 publications

(121 citation statements)

References 20 publications

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“…Both clinical and histopathological differences exist between ocular and extraocular SCs [5]. A recent study by Tripathi et al suggests that there has been an increased incidence of SC among men and white patients [4]. We report a case of a rapidly growing SC on the left cheek in an elderly white male.…”

Section: Introductionmentioning

confidence: 75%

“…Even though SC occurs predominantly periorbitally, extraocular variants form 25% of all SCs. Additionally, extraocular SC and black race have worse prognoses [4]. From the previous literature, it has been observed that extraocular SC has significant clinical and histopathological differences from ocular SC.…”

Section: Discussionmentioning

confidence: 99%

“…More than 70% of extraocular variants of SC occur in the head and neck regions where sebaceous glands are most commonly located [3]. Extraocular variants are aggressive and metastasize more rapidly [4]. Both clinical and histopathological differences exist between ocular and extraocular SCs [5].…”

Section: Introductionmentioning

confidence: 99%

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Extraocular Sebaceous Carcinoma Presenting As a Nodule over the Zygoma

Kraleti

Manyam

Dawson

2020

Cureus

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Section: Introductionmentioning

confidence: 75%

Section: Discussionmentioning

confidence: 99%

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Extraocular Sebaceous Carcinoma Presenting As a Nodule over the Zygoma

Kraleti

Manyam

Dawson

2020

Cureus

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“…Recurrence rates range from 4% to 28%, and the 5‐year survival rates range from 70% to 97% with a 10‐year survival of approximately 79% . Metastatic spread to regional lymph nodes or distant sites involving liver, lung, brain, and bones is seen in 14–25% of patients . Poor prognostic features are multicentric origin, concomitant involvement of upper and lower eyelids, poorly differentiated tumours, lymphovascular and orbital invasion, tumour size larger than 10 mm and intraepithelial pagetoid invasion of the overlying epithelium …”

Section: Sebaceous Carcinomamentioning

confidence: 99%

Update on the pathology, genetics and somatic landscape of sebaceous tumours

et al. 2020

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Cutaneous sebaceous neoplasms show a predilection for the head and neck area of adults and include tumours with benign behaviour, sebaceous adenoma and sebaceoma, and sebaceous carcinoma with potential for an aggressive disease course at the malignant end of the spectrum. The majority of tumours are solitary and sporadic, but a subset of tumours may be associated with Lynch syndrome, also known as hereditary non‐polyposis colon cancer (HNPCC) and previously referred to as Muir‐Torre syndrome (now known to be part of Lynch syndrome). This review provides an overview of the clinical and histological features of cutaneous sebaceous neoplasia with an emphasis on differentiating features and differential diagnosis. It also offers insights into the recently described molecular pathways involved in the development of sebaceous tumours and their association with Lynch syndrome.

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“…Sebaceous carcinoma is a rare cutaneous neoplasm that may manifest as ocular or extraocular [1]. Extraocular SC is rare (25 % of reported cases) and mostly affects the head and neck [2].…”

mentioning

confidence: 99%