Incidence and temporal trends of childhood type 1 diabetes between 1975 and 2012 in Navarre (Spain)

Llenas, Luis Forga; Iriarte, María José Goñi; Contín, Koldo Cambra; Ibáñez, Berta; Guendulain, María Chueca; Zubiri, Sara Berrade

doi:10.1016/j.gaceta.2014.06.010

Cited by 18 publications

(9 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The incidence among boys tends to be higher than among girls in the 10–14 years age group. This was consistent with results reported from some European regions . Because boys reach puberty later than girls, it has been suggested that physiological changes at puberty may act as triggers for diabetes .…”

Section: Discussionsupporting

confidence: 92%

Rapidly rising incidence of Type 1 diabetes in children and adolescents aged 0–19 years in Zhejiang, China, 2007 to 2013

Zhong

et al. 2015

Diabet. Med.

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 92%

Rapidly rising incidence of Type 1 diabetes in children and adolescents aged 0–19 years in Zhejiang, China, 2007 to 2013

Zhong

et al. 2015

Diabet. Med.

View full text Add to dashboard Cite

show abstract

“…29,30 US data 31 suggest an overall annualised incidence from 2001 to 2015 of about 22·9 cases per 100 000 people among those younger than 65 years; data from other regions suggest similar incidences. 32 The greatest observed increases in incidence of type 1 diabetes are among children younger than 15 years, particularly in those younger than 5 years. 33 These increases cannot be explained by genetic changes, implicating environmental or behavioural factors, or both.…”

Section: Epidemiologymentioning

confidence: 99%

Type 1 diabetes

2018

View full text Add to dashboard Cite

Type 1 diabetes is a chronic autoimmune disease characterised by insulin deficiency and resultant hyperglycaemia. Knowledge of type 1 diabetes has rapidly increased over the past 25 years, resulting in a broad understanding about many aspects of the disease, including its genetics, epidemiology, immune and β-cell phenotypes, and disease burden. Interventions to preserve β cells have been tested, and several methods to improve clinical disease management have been assessed. However, wide gaps still exist in our understanding of type 1 diabetes and our ability to standardise clinical care and decrease disease-associated complications and burden. This Seminar gives an overview of the current understanding of the disease and potential future directions for research and care.

show abstract

“…Several studies and organizations have shown an unprecedented increase in the prevalence of diabetes worldwide (NCD-RisC 2016), including T1DM (Harjutsalo et al 2008, Patterson et al 2009, Dabelea et al 2014, Forga Llenas et al 2015, Lamb et al 2015, and the estimated number of adults with diabetes has soared to over 380 million (> 8 % world adult population, > 12% in USA) (Menke et al 2015), with a mean estimation of over 37 % with pre-diabetes and over 45 % undiagnosed according to current diagnostic criteria (Schmidt et al 2011, Federation 2015, Mechanick 2015, Menke 2015. The prevalence of T2DM in younger individuals has also increased worldwide (Holden et al 2013, Menke et al 2015, creating a new class of patients comprising children (Lustig et al 2016), adolescents and young adults (Weiss et al 2013, Song 2016.…”

Section: Definitionmentioning

confidence: 99%

Subclinical Diabetes

Lima

2017

An. Acad. Bras. Ciênc.

View full text Add to dashboard Cite

Type 2 diabetes mellitus (T2DM) is increasing in prevalence worldwide, and those non-diagnosed or misdiagnosed comprise a significant group compared to those diagnosed. Accumulated scientific evidence indicate that the current diagnostic markers (fasting glycemia, 2h glycemia after an oral glucose load and HbA1c) are indeed late diagnostic criteria when considering the incidence of diabetes-related complications and comorbidities, which are also at high risk in some groups among normoglycemic individuals. Additionally, the earlier identification of future risk of diabetes is desirable since it would allow better adherence to preventive actions such as lifestyle intervention, ultimately avoiding complications and minimizing the economic impact/burden on health care expenses. Insulin resistance and hyperhormonemia (insulin, amylin, glucagon) are non-disputable hallmarks of T2DM, which already takes place among these normoglycemic, otherwise health subjects, characterizing a state of subclinical diabetes. Insulin resistance and hyperinsulinemia can be computed from fasting plasma insulin as an independent variable in normoglycemia. An overview of the current diagnostic criteria, disease onset, complications, comorbidities and perspectives on lifestyle interventions are presented. A proposal for early detection of subclinical diabetes from routine evaluation of fasting plasma insulin, which is affordable and robust and thus applicable for the general population, is further suggested.

show abstract

Incidence and temporal trends of childhood type 1 diabetes between 1975 and 2012 in Navarre (Spain)

Abstract: Since the year 2000, the incidence of type 1 diabetes among persons younger than 15 years in Navarre has been very high and has quadrupled over the last four decades.

Cited by 18 publications

References 14 publications

Rapidly rising incidence of Type 1 diabetes in children and adolescents aged 0–19 years in Zhejiang, China, 2007 to 2013

Rapidly rising incidence of Type 1 diabetes in children and adolescents aged 0–19 years in Zhejiang, China, 2007 to 2013

Type 1 diabetes

Subclinical Diabetes

Contact Info

Product

Resources

About