Incidence of aflatoxin M1 in human breast milk in Tehran, Iran

Sadeghi, Naficeh; Oveisi, Mohammad Reza; Jannat, Behrooz; Hajimahmoodi, Mannan; Bonyani, Hengameh; Jannat, Forouzandeh

doi:10.1016/j.foodcont.2008.02.005

Cited by 108 publications

(76 citation statements)

References 8 publications

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“…From 85 to 100 % of children in African countries have either detectable levels of serum AF-alb or urinary aflatoxins (Gong et al 2002;Gong et al 2003;Gong et al 2004;Polychronaki et al 2008;Turner et al 2000;Turner et al 2003;Turner et al 2007;Wild et al 1990;Wild et al 1993). Several studies have also found AFB 1 and AFM 1 in excreted breast milk samples (Afshar et al 2013;El-Tras et al 2011;Gürbay et al 2010;Jonsyn et al 1995b;Polychronaki et al 2006;Polychronaki et al 2007;Sadeghi et al 2009;Tchana et al 2010).…”

Section: Cgiar Agricultural Research On Food Safety and Aflatoxinsmentioning

confidence: 96%

International agricultural research to reduce food risks: case studies on aflatoxins

et al. 2015

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Despite massive expansion of human and livestock populations, fuelled by agricultural innovations, nearly one billion people are hungry and 2 billion are sickened each year from the food they eat. Agricultural and food systems are intimately connected to health outcomes, but health policy and programs often stop at the clinic door. A consensus is growing that the disconnection between agriculture, health and nutrition is at least partly responsible for the disease burden associated with food and farming. Mycotoxins produced by fungi are one of the most serious food safety problems affecting staple crops (especially maize and groundnuts).Aflatoxins, the best studied of these mycotoxins, cause around 90,000 cases of liver cancer each year and are strongly associated with stunting and immune suppression in children. Mycotoxins also cause major economic disruptions through their impacts on trade and livestock production. In this paper we use the case of fungal toxins to explore how agricultural research can produce innovations, understand incentives and enable institutions to improve, simultaneously, food safety, food accessibility for poor consumers and access to markets for smallholder farmers, thus making the case for research investors to support research into agricultural approaches for enhancing food safety in value chains. We first discuss the evolution of food safety research within the CGIAR. Then we show how taking an epidemiological and economic perspective on aflatoxin research connects health and nutrition outcomes. Finally, we present three case studies illustrating the traditional strengths of CGIAR research: breeding better varieties and developing new technologies.

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Section: Cgiar Agricultural Research On Food Safety and Aflatoxinsmentioning

confidence: 96%

International agricultural research to reduce food risks: case studies on aflatoxins

et al. 2015

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“…From 50 samples analyzed, only one was contaminated by AFM 1 at a concentration of 0.024 ng/mL (Navas et al, 2005). In a recent study carried out with 160 lactating mothers in Iran, AFM 1 was detected in 157 samples, with concentrations ranging from 0.3 to 26.7 ng/kg (Sadeghi et al, 2009). Aflatoxins were also detected in samples of umbilical cord blood, demonstrating they can cross the placenta, starting exposure to this carcinogen in the uterus (Wild et al, 1991;Turner et al, 2007).…”

Section: Occurrence Of Aflatoxin Biomarkers In Biological Fluidsmentioning

confidence: 96%

Biomarkers of Aflatoxin Exposure and Its Relationship with the Hepatocellular Carcinoma

Jager¹,

Ramalho²,

Zambelli³

et al. 2011

Aflatoxins - Biochemistry and Molecular Biology

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“…Moreover, AFB1 contamination at higher levels has also been correlated with reduced birth weight and jaundice in neonates [40]. The capacity of biotransformation of carcinogens in infants is generally slower than that of adults, this result in a longer circulation time of the chemicals [41].…”

Section: Health Implications Of Afm1mentioning

confidence: 99%

A Decade of Aflatoxin M1 Surveillance in Milk and Dairy Products in Developing Countries (2001-2011): A Review

Mwanza¹,

Ngoma²,

Nyirenda³

et al. 2013

Mycotoxin and Food Safety in Developing Countries

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Incidence of aflatoxin M1 in human breast milk in Tehran, Iran

Cited by 108 publications

References 8 publications

International agricultural research to reduce food risks: case studies on aflatoxins

International agricultural research to reduce food risks: case studies on aflatoxins

Biomarkers of Aflatoxin Exposure and Its Relationship with the Hepatocellular Carcinoma

A Decade of Aflatoxin M1 Surveillance in Milk and Dairy Products in Developing Countries (2001-2011): A Review

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