Incidence of Guillain-Barré syndrome (GBS) in China: A national population-based study

Zheng, Pei; Tian, De-Cai; Xiu, Yuwen; Wang, Yongjun; Shi, Fu‐Dong

doi:10.1016/j.lanwpc.2021.100302

Cited by 13 publications

(14 citation statements)

References 35 publications

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“…Previous systematic reviews showed that the incidence of paediatric GBS ranges from 0.34 to 1.34 per 100,000 population [15]. In neighbouring East Asia regions, the GBS incidence ranges from 0.233 per 100,000 population in Beijing [33] to 0.66 per 100,000 population in Taiwan [34]. Our study showed an average incidence of 0.62 per 100,000 population.…”

Section: Estimated Incidence Of Paediatric Gbs Is Similar To Neighbou...supporting

confidence: 47%

Guillain-Barré syndrome in children – High occurrence of Miller Fisher syndrome in East Asian region

Chiu

Chan²,

Yau³

et al. 2022

Brain and Development

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Section: Estimated Incidence Of Paediatric Gbs Is Similar To Neighbou...supporting

confidence: 47%

Guillain-Barré syndrome in children – High occurrence of Miller Fisher syndrome in East Asian region

Chiu

Chan²,

Yau³

et al. 2022

Brain and Development

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“…The reported incidence of GBS ranges from 0.81 to 1.89 cases per 100,000 person-years in north America and Europe [ 2 ]. In China, a recently published national incidence for GBS was 0.233 in children and 0.829 in adults per 100,000 [ 3 ]. GBS occurs more frequently in males than in females and the incidence increases with age, although all age groups can be affected.…”

Section: Introductionmentioning

confidence: 99%

Guillain–Barré Syndrome in Northern China: A Retrospective Analysis of 294 Patients from 2015 to 2020

Zhai

Guo

Xue

et al. 2022

JCM

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Objectives: Acute motor axonal neuropathy (AMAN) was first reported to be the main subtype of Guillain–Barré syndrome (GBS) in northern China in the 1990s. About 30 years has passed, and it is unknown whether the disease spectrum has changed over time in northern China. We aimed to study the epidemiological, clinical, and electrophysiological features of GBS in northern China in recent years. Methods: We retrospectively analyzed the medical records of GBS patients admitted to the Second Hospital of Hebei Medical University in northern China from 2015 to 2020. Results: A total of 294 patients with GBS were enrolled, with median age 53 years and 60.5% of participants being male, and a high incidence in summer and autumn. AMAN was still the predominant subtype in northern China (40.1%). The AMAN patients had shorter time to nadir, longer hospitalization time, and a more severe HFGS score at discharge than acute inflammatory demyelinating polyneuropathies (AIDP) (p < 0.05). With SPSS multivariable logistic regression analysis, we found the GBS disability score (at admission), dysphagia, and dysautonomia were independent risk factors for GBS patients requiring MV (p < 0.05). In comparison with other regions, the proportion of AMAN in northern China (40.1%) was higher than in eastern (35%) and southern (19%) China. Conclusions: AMAN is still the predominant subtype in northern China after 30 years, but there have been changes over time in the GBS spectrum since the 1990s. There are regional differences in GBS in China.

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“…As per the prevalence surveys done in Europe, Asia, America, and Australia, 0.4 to 4 GBS cases per 100,000 people have been reported annually [ 2 ]. In Asia, an annual incidence of 1.71, 1.82, 0.42 GBS cases per 100,000 people have been observed in China, South Korea, and Japan respectively [ 3 , 4 ]. These cases have been more frequently reported during the monsoon season in some regions [ 2 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

Guillain-barré syndrome (GBS) with antecedent chikungunya infection: a case report and literature review

V.,

Pattanaik,

Marate

et al. 2024

Neurol. Res. Pract.

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Guillain-Barré Syndrome (GBS) is an autoimmune neuropathy. Antecedent infections have been seen to be significant triggering factors for developing GBS. Among them, arboviral infections are rapidly gaining importance as significant triggers, especially in the areas where they are endemic. Chikungunya, an arboviral infection that usually causes a self-limiting acute febrile illness can lead to GBS as one its severe complications. Herein, we describe a case of a 21-year-old female who presented with weakness in all four limbs and paresthesia. Nerve conduction study and cerebrospinal fluid (CSF) analysis showed axonal, demyelinating motor and sensory neuropathy with albuminocytological dissociation indicating Acute Motor and Sensory Axonal Neuropathy (AMSAN) variant of GBS. Serum IgM antibodies against ganglioside GM1 were detected. Anti-Chikungunya IgM antibodies were found in both serum and CSF samples. The patient was initiated with Intravenous Immunoglobulin (IVIG) therapy. In view of hypoxia, she was intubated and was on mechanical ventilation. After 2 weeks of being comatose, the patient gradually improved and was discharged with no sequelae.A literature review on antecedent infections in GBS is presented alongside the case report to better understand the association of GBS with antecedent infections, especially the endemic arboviral infections like Chikungunya, Dengue and Zika. This will help in reinforcing the significance of having robust surveillance and public health control measures for infectious diseases.

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Incidence of Guillain-Barré syndrome (GBS) in China: A national population-based study

Cited by 13 publications

References 35 publications

Guillain-Barré syndrome in children – High occurrence of Miller Fisher syndrome in East Asian region

Guillain-Barré syndrome in children – High occurrence of Miller Fisher syndrome in East Asian region

Guillain–Barré Syndrome in Northern China: A Retrospective Analysis of 294 Patients from 2015 to 2020

Guillain-barré syndrome (GBS) with antecedent chikungunya infection: a case report and literature review

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